Pathway Talk:WP3656

From WikiPathways

Jump to: navigation, search
Sorting order:
Start a new discussion

Another difficult pathway (1)

There have been no changes to this discussion for at least 30 days. If it is concluded, you may want to write a summary.

This is another pathway that is difficult to illustrate. I think you have to include the central complex multiple times to get the point across, like in the original figure. The second step of the complex should have the addition of PKCz and SQST1. You can then add an interaction from the PKCz node to the anchor on the ATP->ADP conversion. And show that PKCz gets phosphorylated by adding a State on that node in the final complex.

I am not sure about the addition of UBC13, UEV1A and ubiquitin?

You can also illustrate the binding of PKCz and SQST1 before they join the complex, just like in the figure.

Personal tools