Complement and Coagulation Cascades (Pan troglodytes)

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Coagulation CascadeClassical PathwayPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcfibrin degredationproductsClotC3b/4b, C3b, C3dFibrinolytic systemMediatorsCell adhesion,migration,profileration, etcAntibody/antigencomplexLectin PathwayCell adhesion,migration,profileration, etcVascular injuryC3bCollagen,basement membrane,activated platelets, etc.Cross-linkedfibrin polymerKinin kallikrein systemC4aAlternative PathwayDegredationMuscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.Cell lysisC3b/BbComplement CascadeC3aC5aZymosan,insulin, etc.C4b/2aC3Convertasemembrane attack complexThrombinExtrinsic pathwayC3A2MPROCC3AR1F13BADNCR2C1QBC7H2-BFC2BradykininF9SERPINE1FGBF12F7Daf1C4SERPINA5MBL1SERPINA1SERPINC1C4BPBDKRB1VWFCR1CD46F3C6F2F10PLAURMASP2SERPIND1MASP1PLGC1SDaf2C1RPLAUC1QAKLKB1C8GC9PROS1109821F2RSERPING1PLATCD59AF5KNG1C1QCC5AR1CPB2Fibrin monomerCFICRRYF8THBDSERPINF2HcCFHTFPI


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 58% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
89201view04:00, 23 August 2016AriuttaOntology Term : 'hemostasis pathway' added !
89200view04:00, 23 August 2016AriuttaOntology Term : 'coagulation cascade pathway' added !
89199view04:00, 23 August 2016AriuttaOntology Term : 'complement system pathway' added !
71692view19:42, 17 October 2013MaintBotAutomated update of data sources
69308view18:43, 8 July 2013MaintBotUpdated to 2013 gpml schema
41618view02:02, 2 March 2011MaintBotRemoved redundant pathway information and comments
38707view19:28, 23 September 2010AlexanderPico
34346view22:20, 9 December 2009MaintBotAutomatic update of empty xrefs
33587view09:51, 1 December 2009MaintBotRemoved group label
31610view22:13, 13 August 2009MaintBotFixed text labels
30507view21:44, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct465372 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct
BradykininMetabolite
C1QAGeneProduct749231 (Entrez Gene)
C1QBGeneProduct469214 (Entrez Gene)
C1QCGeneProduct456612 (Entrez Gene)
C1RGeneProduct466939 (Entrez Gene)
C1SGeneProduct451808 (Entrez Gene)
C2GeneProduct
C3GeneProduct455644 (Entrez Gene)
C3AR1GeneProduct466942 (Entrez Gene)
C4GeneProduct
C4BPGeneProduct
C5AR1GeneProduct468931 (Entrez Gene)
C6GeneProduct449612 (Entrez Gene)
C7GeneProduct738238 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct
C9GeneProduct
CD46GeneProduct469663 (Entrez Gene)
CD59AGeneProduct
CFHGeneProduct457601 (Entrez Gene)
CFIGeneProduct471271 (Entrez Gene)
CPB2GeneProduct452582 (Entrez Gene)
CR1GeneProduct449643 (Entrez Gene)
CR2GeneProduct457690 (Entrez Gene)
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct452679 (Entrez Gene)
F12GeneProduct462304 (Entrez Gene)
F13BGeneProduct735857 (Entrez Gene)
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
F3GeneProduct457038 (Entrez Gene)
F5GeneProduct457500 (Entrez Gene)
F7GeneProduct744785 (Entrez Gene)
F8GeneProduct473838 (Entrez Gene)
F9GeneProduct465887 (Entrez Gene)
FGBGeneProduct461558 (Entrez Gene)
Fibrin monomerMetabolite
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct493182 (Entrez Gene)
KNG1GeneProduct460916 (Entrez Gene)
MASP1GeneProduct460925 (Entrez Gene)
MASP2GeneProduct736039 (Entrez Gene)
MBL1GeneProduct
PLATGeneProduct472748 (Entrez Gene)
PLAUGeneProduct738078 (Entrez Gene)
PLAURGeneProduct450103 (Entrez Gene)
PLGGeneProduct463117 (Entrez Gene)
PROCGeneProduct459593 (Entrez Gene)
PROS1GeneProduct460533 (Entrez Gene)
SERPINA1GeneProduct467541 (Entrez Gene)
SERPINA5GeneProduct
SERPINC1GeneProduct457528 (Entrez Gene)
SERPIND1GeneProduct745390 (Entrez Gene)
SERPINE1GeneProduct472467 (Entrez Gene)
SERPINF2GeneProduct
SERPING1GeneProduct748148 (Entrez Gene)
TFPIGeneProduct470603 (Entrez Gene)
THBDGeneProduct469898 (Entrez Gene)
VWFGeneProduct451773 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
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