IL-4 signaling Pathway (Mus musculus)

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Molecule in the pathwayMolecular associationCYDExtracellularAcetylationDDReaction through unknown mechanisms/moleculesDesumoylationPlasma membraneCY -> PMAccession Number: NetPath 16ControlDemethylationCytoplasmDEnzyme complexGOMitochondrionPMGolgi apparatusReceptorDProteins in a complex interactionPhosphorylationProteolytic cleavageECCY -> NUDDNucleusRecruitmentDephosphorylationPalmitoylationCY -> PMENERCY -> PMLigandUbiquitinationSumoylation(Protein-protein interaction)MethylationGlycosylationEndosomeDeubiquitinationDeacetylationInhibitionDTranslocationAutophosphorylationActivationEndoplasmic reticulumMTDCY -> PMCY -> NUNUPrkczJak3Socs1Stat6Irs2Socs3Stat6Stat6Il4raMapk1RPS6KB1Jak1HIST2H3CGene SymbolIl2rgPIK3R1StamPik3cdSfpi1Ptpn6Il4Inpp5dFesCrebbpAkt1Jak2Rasa1Grb2Sos1Bcl2l1Atf2Nfkb1Pik3caPik3r2Ptpn11Ptk2Mapk14Ets1LckStat6Mapk11Shc1Mapk3Stat6NCF1Nfkb1Stat5aBadIl4PrkciCxcr4PrkciPlcg1PawrRelaIl13ra1CblSrcSocs5Jak2Mapk14PrkcdAdrbk2PrkcdTyk2Stat1PrkcnFynElk1Dok2Il4raJak1Irs1PrkczPrkcnEp300Hmga1


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
71761view20:27, 17 October 2013MaintBotremoved data source from nodes without identifier
69984view21:31, 11 July 2013MaintBotupdated to 2013 schema
67379view10:44, 26 June 2013Christine ChichesterOntology Term : 'interleukin-4 signaling pathway' added !
41293view00:22, 2 March 2011MaintBotRemoved redundant pathway information and comments
34389view22:50, 9 December 2009MaintBotAutomatic update of empty xrefs
28136view20:04, 27 January 2009KhanspersChanged name
20877view11:30, 14 November 2008MaintBot[[Pathway:Mus musculus:IL-4 NetPath 16]] moved to [[Pathway:WP93]]: Moved to stable identifier
8178view13:46, 7 January 2008MaintBot[[Pathway:Mouse:IL-4 NetPath 16]] moved to [[Pathway:Mus musculus:IL-4 NetPath 16]]: Renaming species
7709view16:11, 18 December 2007MaintBotfixed category names
7248view12:41, 4 November 2007MaintBotAdded categories to GPML
6461view22:19, 22 May 2007A.Pandeygpml file for [[Mouse:IL-4_NetPath_16]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Adrbk2GeneProduct320129 (Entrez Gene)
Akt1GeneProduct11651 (Entrez Gene)
Atf2GeneProduct11909 (Entrez Gene)
BadGeneProduct12015 (Entrez Gene)
Bcl2l1GeneProduct12048 (Entrez Gene)
CblGeneProduct12402 (Entrez Gene)
CrebbpGeneProduct12914 (Entrez Gene)
Cxcr4GeneProduct12767 (Entrez Gene)
Dok2GeneProduct13449 (Entrez Gene)
Elk1GeneProduct13712 (Entrez Gene)
Ep300GeneProduct328572 (Entrez Gene)
Ets1GeneProduct23871 (Entrez Gene)
FesGeneProduct14159 (Entrez Gene)
FynGeneProduct14360 (Entrez Gene)
Gene SymbolGeneProduct
Grb2GeneProduct14784 (Entrez Gene)
HIST2H3CGeneProduct
Hmga1GeneProduct15361 (Entrez Gene)
Il13ra1GeneProduct16164 (Entrez Gene)
Il2rgGeneProduct16186 (Entrez Gene)
Il4GeneProduct16189 (Entrez Gene)
Il4raGeneProduct16190 (Entrez Gene)
Inpp5dGeneProduct16331 (Entrez Gene)
Irs1GeneProduct16367 (Entrez Gene)
Irs2GeneProduct384783 (Entrez Gene)
Jak1GeneProduct16451 (Entrez Gene)
Jak2GeneProduct16452 (Entrez Gene)
Jak3GeneProduct16453 (Entrez Gene)
LckGeneProduct16818 (Entrez Gene)
Mapk11GeneProduct19094 (Entrez Gene)
Mapk1GeneProduct26413 (Entrez Gene)
Mapk14GeneProduct26416 (Entrez Gene)
Mapk3GeneProduct26417 (Entrez Gene)
NCF1GeneProduct17969 (Entrez Gene)
Nfkb1GeneProduct18033 (Entrez Gene)
PIK3R1GeneProduct18708 (Entrez Gene)
PawrGeneProduct114774 (Entrez Gene)
Pik3caGeneProduct18706 (Entrez Gene)
Pik3cdGeneProduct18707 (Entrez Gene)
Pik3r2GeneProduct18709 (Entrez Gene)
Plcg1GeneProduct18803 (Entrez Gene)
PrkcdGeneProduct18753 (Entrez Gene)
PrkciGeneProduct18759 (Entrez Gene)
PrkcnGeneProduct75292 (Entrez Gene)
PrkczGeneProduct18762 (Entrez Gene)
Ptk2GeneProduct14083 (Entrez Gene)
Ptpn11GeneProduct19247 (Entrez Gene)
Ptpn6GeneProduct15170 (Entrez Gene)
RPS6KB1GeneProduct72508 (Entrez Gene)
Rasa1GeneProduct218397 (Entrez Gene)
RelaGeneProduct19697 (Entrez Gene)
Sfpi1GeneProduct20375 (Entrez Gene)
Shc1GeneProduct20416 (Entrez Gene)
Socs1GeneProduct12703 (Entrez Gene)
Socs3GeneProduct12702 (Entrez Gene)
Socs5GeneProduct56468 (Entrez Gene)
Sos1GeneProduct20662 (Entrez Gene)
SrcGeneProduct20779 (Entrez Gene)
StamGeneProduct20844 (Entrez Gene)
Stat1GeneProduct20846 (Entrez Gene)
Stat5aGeneProduct20850 (Entrez Gene)
Stat6GeneProduct20852 (Entrez Gene)
Tyk2GeneProduct54721 (Entrez Gene)

Annotated Interactions

No annotated interactions
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