1-8DNA transcriptionCytokines Production,Apoptosis, etc.Stress: Osmotic shockg-radiation, Anisomycin??FASL, InflammatoryCytokines, UV, etc.Growth Factors, UVTrophic Factors, etc.??Translation?STAT1TGFBR1ApoptosisHSPB1HMGN1TRADDATF2MAP2K4MAPK14RIPK1MAP3K7RASGRF1HRASGRB2MAP3K1MAPK14PLA2G4AMYCMAPKAPK5MAXMAP2K6ELK1CDC42DDIT3TGFB2RAC1RPS6KA5MKNK1CREB1MAPKAPK2MAP3K9SHC1MAP3K5MEF2DTRAF2MAPKAPK2DAXXTranscription factors