TCA Cycle (Pan troglodytes)

From WikiPathways

Jump to: navigation, search
Degradation of Fatty AcidsContaining an Even Number of CarbonsMitochondrionCytosolElectron Transport ChainGluconeogenesisGlycolysisFatty Acid SynthesisDegradation of Fatty AcidsContaining an Odd Number of CarbonsMalateSuccinatePDHA1Acetyl-CoAMalatealpha-KetoglutaratePDK2PDHXSDHCSuccinyl-CoAPDK1SUCLG1PyruvateSUCLG2OGDHOxaloacetateOxaloacetateIDH3BIDH2IDH3GMDH2PDHBSDHDPDP2IsocitratePDK3PDP1DLDSUCLA2FumarateDLATFHDLSTMDH1SDHBPCACO2PDHA2CitrateSDHADLDIDH3APDK4CS


The citric acid cycle, also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both Albert Szent-Gyorgyi and Hans Krebs. [From Wikipedia]


This pathway was inferred from Homo sapiens pathway WP78(r28870) with a 90% conversion rate.

Quality Tags

Ontology Terms



No bibliography


View all...
106925view13:39, 17 September 2019MaintBotHMDB identifier normalization
87719view09:17, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87718view09:16, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
69268view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
41576view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34304view22:06, 9 December 2009MaintBotAutomatic update of empty xrefs
33546view09:39, 1 December 2009MaintBotRemoved group label
31575view22:00, 13 August 2009MaintBotFixed text labels
30450view21:25, 29 July 2009MaintBotNew pathway

External references


View all...
NameTypeDatabase referenceComment
ACO2GeneProduct470193 (Entrez Gene)
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
CSGeneProduct746229 (Entrez Gene)
CitrateMetaboliteHMDB0000094 (HMDB)
DLATGeneProduct466780 (Entrez Gene)
DLDGeneProduct463861 (Entrez Gene)
DLSTGeneProduct453039 (Entrez Gene)
FHGeneProduct457851 (Entrez Gene)
FumarateMetaboliteHMDB0000134 (HMDB)
IDH2GeneProduct453645 (Entrez Gene)
IDH3AGeneProduct453565 (Entrez Gene)
IDH3BGeneProduct458048 (Entrez Gene)
IsocitrateMetaboliteHMDB0000193 (HMDB)
MDH1GeneProduct459271 (Entrez Gene)
MDH2GeneProduct463484 (Entrez Gene)
MalateMetaboliteHMDB0000156 (HMDB)
OGDHGeneProduct738474 (Entrez Gene)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
PDHA1GeneProduct465525 (Entrez Gene)
PDHA2GeneProduct471255 (Entrez Gene)
PDHBGeneProduct470832 (Entrez Gene)
PDHXGeneProduct451120 (Entrez Gene)
PDK1GeneProduct459743 (Entrez Gene)
PDK2GeneProduct468402 (Entrez Gene)
PDK3GeneProduct740576 (Entrez Gene)
PDK4GeneProduct472448 (Entrez Gene)
PDP1GeneProduct472819 (Entrez Gene)
PDP2GeneProduct454147 (Entrez Gene)
PyruvateMetaboliteHMDB0000243 (HMDB)
SDHAGeneProduct750143 (Entrez Gene)
SDHBGeneProduct456526 (Entrez Gene)
SDHCGeneProduct747462 (Entrez Gene)
SDHDGeneProduct451547 (Entrez Gene)
SUCLA2GeneProduct452711 (Entrez Gene)
SUCLG1GeneProduct470417 (Entrez Gene)
SUCLG2GeneProduct460492 (Entrez Gene)
SuccinateMetaboliteHMDB0000254 (HMDB)
Succinyl-CoAMetaboliteHMDB0001022 (HMDB)

Annotated Interactions

No annotated interactions
Personal tools