methylation (Pan troglodytes)

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1, 2S-methylationN-methylationSAM synthesis (co-substrate)O-methylationL-MethionineMAT2BS-AdenosylmethionineSubstrateO-methylated substrateS-methylated substrateS-AdenosylhomocysteineS-AdenosylmethionineATPQ9N2A9_PANTRMAT1AS-AdenosylhomocysteineINMTMAT2ACOMTPhosphateS-AdenosylhomocysteinePhosphateTPMT_PANTRS-AdenosylmethionineNNMTPNMTN-methylated substrate


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP704(r30265) with a 100% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Testa B, Kramer SD; ''The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.''; Chem Biodivers, 2008 PubMed Europe PMC
  2. Weinshilboum RM; ''Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.''; Cell Mol Neurobiol, 2006 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
106920view13:39, 17 September 2019MaintBotHMDB identifier normalization
69233view18:34, 8 July 2013MaintBotUpdated to 2013 gpml schema
58901view04:47, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41537view01:57, 2 March 2011MaintBotRemoved redundant pathway information and comments
33538view09:36, 1 December 2009MaintBotRemoved group label
30443view21:24, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPMetaboliteHMDB0000538 (HMDB)
COMTGeneProductENSPTRG00000014070 (Ensembl)
INMTGeneProductENSPTRG00000019045 (Ensembl)
L-MethionineMetaboliteHMDB0000696 (HMDB)
MAT1AGeneProductENSPTRG00000002682 (Ensembl)
MAT2AGeneProductENSPTRG00000012134 (Ensembl)
MAT2BGeneProductENSPTRG00000017504 (Ensembl)
N-methylated substrateMetabolite
NNMTGeneProductENSPTRG00000004303 (Ensembl)
O-methylated substrateMetabolite
PNMTGeneProductENSPTRG00000009098 (Ensembl)
PhosphateMetaboliteHMDB0001429 (HMDB)
Q9N2A9_PANTRGeneProductENSPTRG00000012503 (Ensembl)
S-AdenosylhomocysteineMetaboliteHMDB0000939 (HMDB)
S-AdenosylmethionineMetaboliteHMDB0001185 (HMDB)
S-methylated substrateMetabolite
SubstrateMetabolite
TPMT_PANTRGeneProductENSPTRG00000017756 (Ensembl)

Annotated Interactions

No annotated interactions
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