Adipogenesis (Pan troglodytes)

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1Possible Lipodystrophy GenesAdipocyte Secretory ProductsMiscellaneousPreadipocyteTranscription Factors/ModulatorsInsulin Action GenesFully Differentiated Adipocyte MarkersGrowth Factors/HormonesDifferentiated adipocyteInhibitors of Preadipocyte to Adipocyte TransitionBMP3LIFRWWTR1ID3NR1H3CUGBP1DLK1ADFPDDIT3AHRIRS1CDKN1ASTAT3PRLRNR3C1IRS3LGADD45ARB1LIPELIFBMP1ASIPPTGISGTF3AE2F4STAT5BHIF1AFASHNF1ABSCL2GH1KLF6MEF2APPARAADIPOQCFDGATA3INSRBL2MBNL1RETNNCOR1IGF1SPOCK1GATA4IL6STCEBPDPPARGPPARDMEF2BEGR2WNT5BAGPAT2ZMPSTE24SLC2A4HMGA1GDF10NAMPTMIXL1STAT1UCP1IRS4BMP4CEBPBAGTLPLEBF1FZD1OSMKLF5RARARORACNTFRGATA2TWIST1LPIN2NCOA1PCK2WNT10BSOCS1NDNMEF2CTNFLOC738157FRZBNR2F1KLF7BMP2LMNASTAT5AIL6RBL1PNPLA3IRS2NCOR2STAT2CTNNB1EPAS1RXRGSTAT6MEF2DSCDSFRP4CEBPAMIFPCK1SREBF1PPARGC1ASMAD3KLF15RXRAFOXO1TRIB3FOXC2SP1SOCS3LOC450614GADD45BTGFB1NCOA2SERPINE1LPIN3LEPLPIN1WNT1CREB1NRIP1CISD1PLINE2F1DVL1


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(r28133) with a 82% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
87027view14:49, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
69293view18:41, 8 July 2013MaintBotUpdated to 2013 gpml schema
41603view02:02, 2 March 2011MaintBotRemoved redundant pathway information and comments
35350view09:03, 12 February 2010MartijnVanIerselModified description
35348view09:01, 12 February 2010MartijnVanIerselAdded lit. ref.
34332view22:15, 9 December 2009MaintBotAutomatic update of empty xrefs
33135view22:39, 26 October 2009Khanspers
30438view21:22, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADFPGeneProduct465012 (Entrez Gene)
ADIPOQGeneProduct471032 (Entrez Gene)
AGPAT2GeneProduct748669 (Entrez Gene)
AGTGeneProduct450104 (Entrez Gene)
AHRGeneProduct463278 (Entrez Gene)
ASIPGeneProduct747368 (Entrez Gene)
BMP1GeneProduct464042 (Entrez Gene)
BMP2GeneProduct458090 (Entrez Gene)
BMP3GeneProduct471189 (Entrez Gene)
BMP4GeneProduct452912 (Entrez Gene)
BSCL2GeneProduct451262 (Entrez Gene)
CDKN1AGeneProduct747442 (Entrez Gene)
CEBPAGeneProduct
CEBPBGeneProduct469969 (Entrez Gene)
CEBPDGeneProduct464163 (Entrez Gene)
CFDGeneProduct455533 (Entrez Gene)
CISD1GeneProduct450472 (Entrez Gene)
CNTFRGeneProduct
CREB1GeneProduct459901 (Entrez Gene)
CTNNB1GeneProduct450183 (Entrez Gene)
CUGBP1GeneProduct
DDIT3GeneProduct452017 (Entrez Gene)
DLK1GeneProduct
DVL1GeneProduct457191 (Entrez Gene)
E2F1GeneProduct
E2F4GeneProduct454158 (Entrez Gene)
EBF1GeneProduct462229 (Entrez Gene)
EGR2GeneProduct745846 (Entrez Gene)
EPAS1GeneProduct459204 (Entrez Gene)
FASGeneProduct738331 (Entrez Gene)
FOXC2GeneProduct468058 (Entrez Gene)
FOXO1GeneProduct467352 (Entrez Gene)
FRZBGeneProduct742552 (Entrez Gene)
FZD1GeneProduct463524 (Entrez Gene)
GADD45AGeneProduct456929 (Entrez Gene)
GADD45BGeneProduct744311 (Entrez Gene)
GATA2GeneProduct460672 (Entrez Gene)
GATA3GeneProduct450296 (Entrez Gene)
GATA4GeneProduct472698 (Entrez Gene)
GDF10GeneProduct735795 (Entrez Gene)
GH1GeneProduct
GTF3AGeneProduct467243 (Entrez Gene)
HIF1AGeneProduct746195 (Entrez Gene)
HMGA1GeneProduct746594 (Entrez Gene)
HNF1AGeneProduct744121 (Entrez Gene)
ID3GeneProduct745532 (Entrez Gene)
IGF1GeneProduct741055 (Entrez Gene)
IL6GeneProduct463288 (Entrez Gene)
IL6STGeneProduct461866 (Entrez Gene)
INSGeneProduct449570 (Entrez Gene)
IRS1GeneProduct459985 (Entrez Gene)
IRS2GeneProduct452657 (Entrez Gene)
IRS3LGeneProduct
IRS4GeneProduct
KLF15GeneProduct
KLF5GeneProduct452597 (Entrez Gene)
KLF6GeneProduct450269 (Entrez Gene)
KLF7GeneProduct459900 (Entrez Gene)
LEPGeneProduct449638 (Entrez Gene)
LIFGeneProduct736309 (Entrez Gene)
LIFRGeneProduct738797 (Entrez Gene)
LIPEGeneProduct
LMNAGeneProduct457385 (Entrez Gene)
LOC450614GeneProduct450614 (Entrez Gene)
LOC738157GeneProduct738157 (Entrez Gene)
LPIN1GeneProduct459036 (Entrez Gene)
LPIN2GeneProduct455317 (Entrez Gene)
LPIN3GeneProduct
LPLGeneProduct464031 (Entrez Gene)
MBNL1GeneProduct460787 (Entrez Gene)
MEF2AGeneProduct453680 (Entrez Gene)
MEF2BGeneProduct455871 (Entrez Gene)
MEF2CGeneProduct461760 (Entrez Gene)
MEF2DGeneProduct457396 (Entrez Gene)
MIFGeneProduct748716 (Entrez Gene)
MIXL1GeneProduct737620 (Entrez Gene)
NAMPTGeneProduct463648 (Entrez Gene)
NCOA1GeneProduct459068 (Entrez Gene)
NCOA2GeneProduct464226 (Entrez Gene)
NCOR1GeneProduct741384 (Entrez Gene)
NCOR2GeneProduct467150 (Entrez Gene)
NDNGeneProduct453273 (Entrez Gene)
NR1H3GeneProduct466507 (Entrez Gene)
NR2F1GeneProduct461753 (Entrez Gene)
NR3C1GeneProduct471681 (Entrez Gene)
NRIP1GeneProduct474071 (Entrez Gene)
OSMGeneProduct736338 (Entrez Gene)
PCK1GeneProduct458362 (Entrez Gene)
PCK2GeneProduct452807 (Entrez Gene)
PLINGeneProduct467755 (Entrez Gene)
PNPLA3GeneProduct458896 (Entrez Gene)
PPARAGeneProduct458910 (Entrez Gene)
PPARDGeneProduct463188 (Entrez Gene)
PPARGGeneProduct460178 (Entrez Gene)
PPARGC1AGeneProduct
PRLRGeneProduct461925 (Entrez Gene)
PTGISGeneProduct458323 (Entrez Gene)
RARAGeneProduct454647 (Entrez Gene)
RB1GeneProduct452715 (Entrez Gene)
RBL1GeneProduct735916 (Entrez Gene)
RBL2GeneProduct467978 (Entrez Gene)
RETNGeneProduct742100 (Entrez Gene)
RORAGeneProduct747433 (Entrez Gene)
RXRAGeneProduct464834 (Entrez Gene)
RXRGGeneProduct457476 (Entrez Gene)
SCDGeneProduct450676 (Entrez Gene)
SERPINE1GeneProduct472467 (Entrez Gene)
SFRP4GeneProduct463356 (Entrez Gene)
SLC2A4GeneProduct468443 (Entrez Gene)
SMAD3GeneProduct748161 (Entrez Gene)
SOCS1GeneProduct737070 (Entrez Gene)
SOCS3GeneProduct454921 (Entrez Gene)
SP1GeneProduct451939 (Entrez Gene)
SPOCK1GeneProduct462085 (Entrez Gene)
SREBF1GeneProduct454480 (Entrez Gene)
STAT1GeneProduct459834 (Entrez Gene)
STAT2GeneProduct451996 (Entrez Gene)
STAT3GeneProduct454682 (Entrez Gene)
STAT5AGeneProduct454681 (Entrez Gene)
STAT5BGeneProduct454679 (Entrez Gene)
STAT6GeneProduct452005 (Entrez Gene)
TGFB1GeneProduct456060 (Entrez Gene)
TNFGeneProduct744399 (Entrez Gene)
TRIB3GeneProduct745623 (Entrez Gene)
TWIST1GeneProduct450135 (Entrez Gene)
UCP1GeneProduct461504 (Entrez Gene)
WNT10BGeneProduct451870 (Entrez Gene)
WNT1GeneProduct742674 (Entrez Gene)
WNT5BGeneProduct467191 (Entrez Gene)
WWTR1GeneProduct
ZMPSTE24GeneProduct456790 (Entrez Gene)

Annotated Interactions

No annotated interactions
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