G Protein Signaling Pathways (Gallus gallus)

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1, 2CellResponseCytoskeletalChangesProtein Kinase CCellResponseTranscriptionTranscriptionG betaGqGiGscAMPPhosphodiesterasesProtein Kinase AAdenylate CyclasesAKAPsPhosphatase 2BG gammaG12/13GNALAKAP11GNA14PDE8APDE7BGNAZGNAI3Ca2+GNAO1PDE8BPPP3CAGNG4IP3RCJMB04_6n13DAGGNG10GNB2cAMPPDE1BRHOARRASPRKCBGNGT2PDE4BKRASCALM1ADCY4AKAP8PDE4CADCY6ITPR1GNG12PRKD3AKAP10GNB5PRKACBAKAP1GNG13GNG5AKAP7AKAP3PRKAR1AGNA12AKAP4GNG11RCJMB04_12k21AKAP2AKAP9GNGT1GNA11ADCY2PPP3CCPPP3CCPRKCEPRKAR2ASLC9A1AKAP6ADCY5PRKCQPDE4AKCNJ3ADCY7RCJMB04_5a10ADCY8PRKCDNRASGNB3GNAO1PDE1AADCY1AKAP13PDE1CAKAP12GNAI1GNASGNAI1PRKAR2BGNAI2GNA15GNA13GNG8RCJMB04_16p24PRKAR1BRCJMB04_23b22ARHGEF1PRKACGPRKACAGNG3ADCY9AKAP5PRKCHHRASADCY3PRKCGPDE7APLCB3PDE4DPRKCZGNG7


Description

G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades.

G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes.

Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP35(r20751) with a 67% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Stryer L, Bourne HR; ''G proteins: a family of signal transducers.''; Annu Rev Cell Biol, 1986 PubMed Europe PMC
  2. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
106124view12:02, 16 August 2019MaintBotHMDB identifier normalization
72068view17:34, 24 October 2013MaintBotUpdated data sources
68871view17:22, 8 July 2013MaintBotUpdated to 2013 gpml schema
67263view10:28, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway' added !
41011view22:57, 1 March 2011MaintBotRemoved redundant pathway information and comments
35317view08:18, 12 February 2010ThomasModified description
35315view08:17, 12 February 2010Thomasadded literature
33932view18:11, 9 December 2009MaintBotAutomatic update of empty xrefs
33487view15:09, 30 November 2009MaintBotRemoved group label
31536view21:46, 13 August 2009MaintBotFixed text labels
30382view21:03, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADCY1GeneProduct420788 (Entrez Gene)
ADCY2GeneProduct420935 (Entrez Gene)
ADCY3GeneProduct422013 (Entrez Gene)
ADCY4GeneProduct
ADCY5GeneProduct395340 (Entrez Gene)
ADCY6GeneProduct
ADCY7GeneProduct415732 (Entrez Gene)
ADCY8GeneProduct420328 (Entrez Gene)
ADCY9GeneProduct395339 (Entrez Gene)
AKAP10GeneProduct417612 (Entrez Gene)
AKAP11GeneProduct418835 (Entrez Gene)
AKAP12GeneProduct421634 (Entrez Gene)
AKAP13GeneProduct415502 (Entrez Gene)
AKAP1GeneProduct417668 (Entrez Gene)
AKAP2GeneProduct
AKAP3GeneProduct
AKAP4GeneProduct
AKAP5GeneProduct428917 (Entrez Gene)
AKAP6GeneProduct423314 (Entrez Gene)
AKAP7GeneProduct426926 (Entrez Gene)
AKAP8GeneProduct426167 (Entrez Gene)
AKAP9GeneProduct395695 (Entrez Gene)
ARHGEF1GeneProduct
CALM1GeneProduct396523 (Entrez Gene)
Ca2+MetaboliteHMDB0000464 (HMDB)
DAGMetaboliteC00165 (KEGG Compound)
GNA11GeneProduct374077 (Entrez Gene)
GNA12GeneProduct769924 (Entrez Gene)
GNA13GeneProduct417434 (Entrez Gene)
GNA14GeneProduct431611 (Entrez Gene)
GNA15GeneProduct
GNAI1GeneProduct396368 (Entrez Gene)
GNAI2GeneProduct396367 (Entrez Gene)
GNAI3GeneProduct374097 (Entrez Gene)
GNALGeneProduct474379 (Entrez Gene)
GNAO1GeneProduct415698 (Entrez Gene)
GNASGeneProduct419313 (Entrez Gene)
GNAZGeneProduct770226 (Entrez Gene)
GNB2GeneProduct
GNB3GeneProduct427945 (Entrez Gene)
GNB5GeneProduct415417 (Entrez Gene)
GNG10GeneProduct769603 (Entrez Gene)
GNG11GeneProduct771999 (Entrez Gene)
GNG12GeneProduct772239 (Entrez Gene)
GNG13GeneProduct771014 (Entrez Gene)
GNG3GeneProduct
GNG4GeneProduct771582 (Entrez Gene)
GNG5GeneProduct424538 (Entrez Gene)
GNG7GeneProduct
GNG8GeneProduct
GNGT1GeneProduct
GNGT2GeneProduct
HRASGeneProduct396229 (Entrez Gene)
IP3MetaboliteHMDB0001143 (HMDB)
ITPR1GeneProduct395412 (Entrez Gene)
KCNJ3GeneProduct396369 (Entrez Gene)
KRASGeneProduct418207 (Entrez Gene)
NRASGeneProduct419885 (Entrez Gene)
PDE1AGeneProduct424116 (Entrez Gene)
PDE1BGeneProduct
PDE1CGeneProduct420752 (Entrez Gene)
PDE4AGeneProduct
PDE4BGeneProduct424700 (Entrez Gene)
PDE4CGeneProduct
PDE4DGeneProduct
PDE7AGeneProduct425199 (Entrez Gene)
PDE7BGeneProduct421692 (Entrez Gene)
PDE8AGeneProduct415455 (Entrez Gene)
PDE8BGeneProduct427645 (Entrez Gene)
PLCB3GeneProduct
PPP3CAGeneProduct395113 (Entrez Gene)
PPP3CCGeneProduct
PRKACAGeneProduct
PRKACBGeneProduct424542 (Entrez Gene)
PRKACGGeneProduct
PRKAR1AGeneProduct417438 (Entrez Gene)
PRKAR1BGeneProduct416446 (Entrez Gene)
PRKAR2AGeneProduct416062 (Entrez Gene)
PRKAR2BGeneProduct769420 (Entrez Gene)
PRKCBGeneProduct416567 (Entrez Gene)
PRKCDGeneProduct415905 (Entrez Gene)
PRKCEGeneProduct421409 (Entrez Gene)
PRKCGGeneProduct
PRKCHGeneProduct423518 (Entrez Gene)
PRKCQGeneProduct
PRKCZGeneProduct419399 (Entrez Gene)
PRKD3GeneProduct421478 (Entrez Gene)
RCJMB04_12k21GeneProduct423302 (Entrez Gene)
RCJMB04_16p24GeneProduct424991 (Entrez Gene)
RCJMB04_23b22GeneProduct427262 (Entrez Gene)
RCJMB04_5a10GeneProduct417430 (Entrez Gene)
RCJMB04_6n13GeneProduct419402 (Entrez Gene)
RHOAGeneProduct395442 (Entrez Gene)
RRASGeneProduct
SLC9A1GeneProduct419580 (Entrez Gene)
cAMPMetaboliteHMDB0000058 (HMDB)

Annotated Interactions

No annotated interactions
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