T Cell Receptor Signaling Pathway (Gallus gallus)

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MethylationReceptorDesumoylationCY->PMMitochondrionReaction through unknown mechanisms/moleculesUbiquitinationDRecruitmentProteolytic cleavageEndosomeCY->NUExtracellularEndoplasmic reticulumPalmitoylationGene SymbolPhosphorylationGolgi apparatusSumoylationER(Protein-protein interaction)LigandInhibitionDeubiquitinationCY->NUDeacetylationTranslocationGODephosphorylationENPlasma membraneMolecule in the pathwayActivationDGlycosylationDemethylationMolecular associationAcetylationNucleusProteins in a complex interactionAutophosphorylationECAccession Number: NetPath_11CYNUControlMTEnzyme complexPMCytoplasmAntigenNU->CYLATPIK3R2GIT2BRAFRCJMB04_17i9PTPN22FOSSH2D3CWIPF1PAK1LIME1TRA@PTPRJDEF6TUBA4AJUNBCL10CD3DCRKFCRL3SCAP1RCJMB04_19o18RAPGEF1CD2PTPRHTUBBJAK3CISHCBLBRCJMB04_25c5VAV2DOCK2CD3ECD4UNC119CARD11MUC1SRCSIT1CD2APCBLSLA2PRKCQENAHMAP4K1ACP1TRAT1CEBPBGAB2CABIN1FYBVASPSHC1NEDD9AKT1MAP2K2CD8AHDAC7ALCP2CD5CD247GRAP2PTK2BHOMER3TRB@PTPN6VAV3PTPN12DNM2FYBCD3EGRB2SKAP2NFAM1CRKLPTPN11STAT5APTPN3SH2D2AEVLPXNRASA1YWHAQARHGEF6MAP2K1PTK2ZAP70KHDRBS1CD3GSTAT5ACREB1SOS1SH3BP2RAP1AVAV1DBNLRASGRP2NFATC2RIPK2PSTPIP1MAPK7ARHGDIBSHBJUNLAX1LNKMAP3K1ITKCDC42STAT5BPAG1DLG1STAT5BPIK3R1FYNSLALIME1LYNCTNNB1TXKPTPRCSTK39ABL1PLCG1RCJMB04_24n15MAPK1ARHGEF7GRAPCREBBPSOS2DTX1RAC2NCLCD247LCKNCK1MAPK3DUSP3ITPR1HDAC7ANCK1LCP2PRKD2WASLOC426359


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP69(r20823) with a 71% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
87700view09:00, 25 July 2016MirellaKalafatiOntology Term : 'T cell' added !
87699view09:00, 25 July 2016MirellaKalafatiOntology Term : 'signaling pathway' added !
68862view17:21, 8 July 2013MaintBotUpdated to 2013 gpml schema
41000view22:56, 1 March 2011MaintBotRemoved redundant pathway information and comments
33921view18:07, 9 December 2009MaintBotAutomatic update of empty xrefs
31512view21:37, 13 August 2009MaintBotFixed text labels
30349view20:52, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABL1GeneProduct417181 (Entrez Gene)
ACP1GeneProduct421909 (Entrez Gene)
AKT1GeneProduct395928 (Entrez Gene)
ARHGDIBGeneProduct417941 (Entrez Gene)
ARHGEF6GeneProduct422247 (Entrez Gene)
ARHGEF7GeneProduct418761 (Entrez Gene)
BCL10GeneProduct424528 (Entrez Gene)
BRAFGeneProduct396239 (Entrez Gene)
CABIN1GeneProduct416938 (Entrez Gene)
CARD11GeneProduct416476 (Entrez Gene)
CBLGeneProduct374038 (Entrez Gene)
CBLBGeneProduct418406 (Entrez Gene)
CD247GeneProduct395911 (Entrez Gene)
CD2GeneProduct768858 (Entrez Gene)
CD2APGeneProduct771715 (Entrez Gene)
CD3DGeneProduct396518 (Entrez Gene)
CD3EGeneProduct396062 (Entrez Gene)
CD3GGeneProduct
CD4GeneProduct395362 (Entrez Gene)
CD5GeneProduct395757 (Entrez Gene)
CD8AGeneProduct403158 (Entrez Gene)
CDC42GeneProduct395917 (Entrez Gene)
CEBPBGeneProduct396185 (Entrez Gene)
CISHGeneProduct395335 (Entrez Gene)
CREB1GeneProduct395099 (Entrez Gene)
CREBBPGeneProduct416667 (Entrez Gene)
CRKGeneProduct417553 (Entrez Gene)
CRKLGeneProduct416939 (Entrez Gene)
CTNNB1GeneProduct395964 (Entrez Gene)
DBNLGeneProduct425994 (Entrez Gene)
DEF6GeneProduct419893 (Entrez Gene)
DLG1GeneProduct424890 (Entrez Gene)
DNM2GeneProduct
DOCK2GeneProduct427612 (Entrez Gene)
DTX1GeneProduct
DUSP3GeneProduct425527 (Entrez Gene)
ENAHGeneProduct374180 (Entrez Gene)
EVLGeneProduct423453 (Entrez Gene)
FCRL3GeneProduct
FOSGeneProduct396512 (Entrez Gene)
FYBGeneProduct427448 (Entrez Gene)
FYNGeneProduct396294 (Entrez Gene)
GAB2GeneProduct419027 (Entrez Gene)
GIT2GeneProduct374035 (Entrez Gene)
GRAP2GeneProduct770756 (Entrez Gene)
GRAPGeneProduct416523 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
HDAC7AGeneProduct426885 (Entrez Gene)
HOMER3GeneProduct420115 (Entrez Gene)
ITKGeneProduct416247 (Entrez Gene)
ITPR1GeneProduct395412 (Entrez Gene)
JAK3GeneProduct395845 (Entrez Gene)
JUNGeneProduct424673 (Entrez Gene)
KHDRBS1GeneProduct374071 (Entrez Gene)
LATGeneProduct
LAX1GeneProduct
LCKGeneProduct
LCP2GeneProduct395438 (Entrez Gene)
LIME1GeneProduct
LNKGeneProduct
LOC426359GeneProduct426359 (Entrez Gene)
LYNGeneProduct421127 (Entrez Gene)
MAP2K1GeneProduct415549 (Entrez Gene)
MAP2K2GeneProduct396349 (Entrez Gene)
MAP3K1GeneProduct427144 (Entrez Gene)
MAP4K1GeneProduct
MAPK1GeneProduct373953 (Entrez Gene)
MAPK3GeneProduct
MAPK7GeneProduct
MUC1GeneProduct426412 (Entrez Gene)
NCK1GeneProduct
NCLGeneProduct396201 (Entrez Gene)
NEDD9GeneProduct395736 (Entrez Gene)
NFAM1GeneProduct417979 (Entrez Gene)
NFATC2GeneProduct419346 (Entrez Gene)
PAG1GeneProduct420195 (Entrez Gene)
PAK1GeneProduct419083 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PLCG1GeneProduct
PRKCQGeneProduct
PRKD2GeneProduct
PSTPIP1GeneProduct415349 (Entrez Gene)
PTK2GeneProduct396416 (Entrez Gene)
PTK2BGeneProduct421998 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN12GeneProduct417725 (Entrez Gene)
PTPN22GeneProduct772032 (Entrez Gene)
PTPN3GeneProduct420963 (Entrez Gene)
PTPN6GeneProduct427947 (Entrez Gene)
PTPRCGeneProduct386580 (Entrez Gene)
PTPRHGeneProduct
PTPRJGeneProduct395330 (Entrez Gene)
PXNGeneProduct395832 (Entrez Gene)
RAC2GeneProduct418044 (Entrez Gene)
RAP1AGeneProduct419867 (Entrez Gene)
RAPGEF1GeneProduct417173 (Entrez Gene)
RASA1GeneProduct427327 (Entrez Gene)
RASGRP2GeneProduct
RCJMB04_17i9GeneProduct424044 (Entrez Gene)
RCJMB04_19o18GeneProduct427272 (Entrez Gene)
RCJMB04_24n15GeneProduct378890 (Entrez Gene)
RCJMB04_25c5GeneProduct420489 (Entrez Gene)
RIPK2GeneProduct420215 (Entrez Gene)
SCAP1GeneProduct
SH2D2AGeneProduct425978 (Entrez Gene)
SH2D3CGeneProduct417225 (Entrez Gene)
SH3BP2GeneProduct422883 (Entrez Gene)
SHBGeneProduct427280 (Entrez Gene)
SHC1GeneProduct395934 (Entrez Gene)
SIT1GeneProduct
SKAP2GeneProduct420629 (Entrez Gene)
SLA2GeneProduct
SLAGeneProduct378908 (Entrez Gene)
SOS1GeneProduct425964 (Entrez Gene)
SOS2GeneProduct423572 (Entrez Gene)
SRCGeneProduct396442 (Entrez Gene)
STAT5AGeneProduct
STAT5BGeneProduct395556 (Entrez Gene)
STK39GeneProduct424173 (Entrez Gene)
TRA@GeneProduct426107 (Entrez Gene)
TRAT1GeneProduct418412 (Entrez Gene)
TRB@GeneProduct
TUBA4AGeneProduct416694 (Entrez Gene)
TUBBGeneProduct
TXKGeneProduct770387 (Entrez Gene)
UNC119GeneProduct771690 (Entrez Gene)
VASPGeneProduct
VAV1GeneProduct
VAV2GeneProduct373938 (Entrez Gene)
VAV3GeneProduct373939 (Entrez Gene)
WASGeneProduct
WIPF1GeneProduct424143 (Entrez Gene)
YWHAQGeneProduct421932 (Entrez Gene)
ZAP70GeneProduct420086 (Entrez Gene)

Annotated Interactions

No annotated interactions
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