TCA Cycle (Gallus gallus)

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Degradation of Fatty AcidsContaining an Even Number of CarbonsGluconeogenesisGlycolysisMitochondrionFatty Acid SynthesisCytosolElectron Transport ChainDegradation of Fatty AcidsContaining an Odd Number of CarbonsDLATMalateSDHCSUCLG2MDH2RCJMB04_4o20SUCLG1OxaloacetatePDK2FHIDH3GACO2OxaloacetateFumarateMalatePDK3SuccinatePCPDHBIDH3ARCJMB04_39i8PDP2PyruvateIDH2DLDCitrateMDH1Succinyl-CoARCJMB04_9n20SDHBPDHA2PDK4RCJMB04_19j12PPM2CSDHAAcetyl-CoAIsocitrateDLDSDHDRCJMB04_17g4SUCLA2CSPDHA1alpha-Ketoglutarate


Description

The citric acid cycle, also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both Albert Szent-Gyorgyi and Hans Krebs. [From Wikipedia]

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP78(r28870) with a 75% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
106114view12:02, 16 August 2019MaintBotHMDB identifier normalization
87717view09:15, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87716view09:15, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
68816view17:16, 8 July 2013MaintBotUpdated to 2013 gpml schema
40951view22:53, 1 March 2011MaintBotRemoved redundant pathway information and comments
33878view17:52, 9 December 2009MaintBotAutomatic update of empty xrefs
33453view15:00, 30 November 2009MaintBotRemoved group label
31505view21:34, 13 August 2009MaintBotFixed text labels
30339view20:48, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ACO2GeneProduct374009 (Entrez Gene)
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
CSGeneProduct100310659 (Entrez Gene)
CitrateMetaboliteHMDB0000094 (HMDB)
DLATGeneProduct419796 (Entrez Gene)
DLDGeneProduct417699 (Entrez Gene)
FHGeneProduct420969 (Entrez Gene)
FumarateMetaboliteHMDB0000134 (HMDB)
IDH2GeneProduct
IDH3AGeneProduct415362 (Entrez Gene)
IDH3GGeneProduct
IsocitrateMetaboliteHMDB0000193 (HMDB)
MDH1GeneProduct421281 (Entrez Gene)
MDH2GeneProduct417517 (Entrez Gene)
MalateMetaboliteHMDB0000156 (HMDB)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
PCGeneProduct
PDHA1GeneProduct418610 (Entrez Gene)
PDHA2GeneProduct
PDHBGeneProduct416066 (Entrez Gene)
PDK2GeneProduct
PDK3GeneProduct418595 (Entrez Gene)
PDK4GeneProduct420570 (Entrez Gene)
PDP2GeneProduct427550 (Entrez Gene)
PPM2CGeneProduct428372 (Entrez Gene)
PyruvateMetaboliteHMDB0000243 (HMDB)
RCJMB04_17g4GeneProduct423154 (Entrez Gene)
RCJMB04_19j12GeneProduct426429 (Entrez Gene)
RCJMB04_39i8GeneProduct423357 (Entrez Gene)
RCJMB04_4o20GeneProduct425972 (Entrez Gene)
RCJMB04_9n20GeneProduct426573 (Entrez Gene)
SDHAGeneProduct395758 (Entrez Gene)
SDHBGeneProduct770063 (Entrez Gene)
SDHCGeneProduct
SDHDGeneProduct419793 (Entrez Gene)
SUCLA2GeneProduct418857 (Entrez Gene)
SUCLG1GeneProduct422932 (Entrez Gene)
SUCLG2GeneProduct416087 (Entrez Gene)
SuccinateMetaboliteHMDB0000254 (HMDB)
Succinyl-CoAMetaboliteHMDB0001022 (HMDB)
alpha-KetoglutarateMetabolite

Annotated Interactions

No annotated interactions
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