Prostaglandin Synthesis and Regulation (Gallus gallus)

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Cell MembranePhospholipidsCytoplasmPG SynthasesInactive MetabolitesprolactinreleaseCortisoneGq signalingpathwayEDNRAPTGER4PTGS2PLA2G4AProstaglandin H2Arachidonic AcidANXA4CYP11A1TXA2SCGB1A1HSD11B1CortisolANXA8CortisolPGF2aPTGER1TBXAS1ANXA6HSD11B2PTGER2PGE2CalciumPGF2aEDNRBPTGIREDN1S100A6PTGS1PRLANXA1ProgesteroneANXA2ANXA5CalciumPTGER3PTGDSPGI2S100A10ANXA3HPGDPTGDRPTGFRPTGIS


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 52% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
106112view12:01, 16 August 2019MaintBotHMDB identifier normalization
87609view08:54, 25 July 2016LindarieswijkOntology Term : 'prostaglandin biosynthetic pathway' added !
87607view08:54, 25 July 2016LindarieswijkOntology Term : 'prostaglandin signaling pathway' added !
74195view13:08, 4 April 2014EgonwRemoved a data source where no ID was given.
68805view17:15, 8 July 2013MaintBotUpdated to 2013 gpml schema
40938view22:52, 1 March 2011MaintBotRemoved redundant pathway information and comments
33867view17:48, 9 December 2009MaintBotAutomatic update of empty xrefs
33450view15:00, 30 November 2009MaintBotRemoved group label
31503view21:34, 13 August 2009MaintBotFixed text labels
30336view20:48, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ANXA1GeneProduct404271 (Entrez Gene)
ANXA2GeneProduct396297 (Entrez Gene)
ANXA3GeneProduct
ANXA4GeneProduct
ANXA5GeneProduct428767 (Entrez Gene)
ANXA6GeneProduct395481 (Entrez Gene)
ANXA8GeneProduct
Arachidonic AcidMetabolite
CYP11A1GeneProduct414838 (Entrez Gene)
CalciumMetaboliteHMDB0000464 (HMDB)
CortisolMetabolite
EDN1GeneProduct420854 (Entrez Gene) PMID: 1474344
EDNRAGeneProduct373908 (Entrez Gene)
EDNRBGeneProduct408082 (Entrez Gene)
HPGDGeneProduct422567 (Entrez Gene)
HSD11B1GeneProduct419861 (Entrez Gene)
HSD11B2GeneProduct
PGE2MetaboliteHMDB0003175 (HMDB)
PGF2aMetaboliteHMDB0001139 (HMDB)
PGI2MetaboliteHMDB0001335 (HMDB)
PLA2G4AGeneProduct396394 (Entrez Gene)
PRLGeneProduct396453 (Entrez Gene)
PTGDRGeneProduct
PTGDSGeneProduct374110 (Entrez Gene)
PTGER1GeneProduct
PTGER2GeneProduct100034745 (Entrez Gene)
PTGER3GeneProduct429116 (Entrez Gene)
PTGER4GeneProduct427183 (Entrez Gene)
PTGFRGeneProduct424548 (Entrez Gene)
PTGIRGeneProduct
PTGISGeneProduct
PTGS1GeneProduct427752 (Entrez Gene)
PTGS2GeneProduct396451 (Entrez Gene)
ProgesteroneMetabolite
Prostaglandin H2Metabolite
S100A10GeneProduct396506 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
S100A6GeneProduct373951 (Entrez Gene)
SCGB1A1GeneProductPMID: 7615804, PMID: 3292559
TBXAS1GeneProduct418101 (Entrez Gene)
TXA2MetaboliteHMDB0001452 (HMDB)

Annotated Interactions

No annotated interactions
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