Adipogenesis (Gallus gallus)

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1Differentiated adipocytePreadipocytePossible Lipodystrophy GenesGrowth Factors/HormonesFully Differentiated Adipocyte MarkersAdipocyte Secretory ProductsTranscription Factors/ModulatorsInhibitors of Preadipocyte to Adipocyte TransitionMiscellaneousInsulin Action GenesBMP1SOCS3AHRMIXL1LPIN3RXRAPRLRSTAT5ARBL2DLK1EBF1WWTR1ADFPNCOA2NRIP1STAT5BCEBPAPLINDFLPIN1NR3C1GADD45BMEF2CRETNIRS3LWNT10BADPNLPLFZD1IRS1CREB1CUGBP1GATA2NCOA1RB1LEPFASRXRGGTF3ALIFRTWIST1KLF7INSIGF1SPOCK1CNTFRGADD45AGATA3PPARGNCOR2CTNNB1BSCL2LMNATGFB1E2F1CISD1FRZBPPARDSTAT3OSMGDF10BMP2DDIT3ADIPOQRARAKLF15WNT1IL6STNDNCYP26B1NR2F1SOCS1RBL1SLC2A4ZMPSTE24FOXC2LIPEGH1RCJMB04_17i9BMP3MEF2AMEF2DCEBPBHNF1ATRIB3HIF1ACEBPDIRS4ID3HMGA1SREBF1RORAPCK2SFRP4PPARARCJMB04_8n15EGR2RCJMB04_2d20STAT2MEF2BE2F4SERPINE1KLF6PCK1ASIPLPIN2NR1H3KLF5WNT5BNCOR1CYP26A1BMP4RCJMB04_6p13FOXO1ACDKN1ASTAT6LIFIL6TNFPPARGC1AMIFIRS2SCDAGPAT2UCP1PTGISGATA4EPAS1SP1AGTSMAD3


Description

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP236(r28133) with a 64% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Rosen ED, Spiegelman BM; ''Molecular regulation of adipogenesis.''; Annu Rev Cell Dev Biol, 2000 PubMed

History

View all...
CompareRevisionActionTimeUserComment
87028view14:50, 15 July 2016MkutmonOntology Term : 'signaling pathway pertinent to development' added !
68817view17:16, 8 July 2013MaintBotUpdated to 2013 gpml schema
40952view22:53, 1 March 2011MaintBotRemoved redundant pathway information and comments
35351view09:03, 12 February 2010MartijnVanIerselModified description
35347view09:00, 12 February 2010MartijnVanIerselAdded lit. ref.
33879view17:52, 9 December 2009MaintBotAutomatic update of empty xrefs
30330view20:46, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADFPGeneProduct427237 (Entrez Gene)
ADIPOQGeneProduct404536 (Entrez Gene)
ADPNGeneProduct
AGPAT2GeneProduct772114 (Entrez Gene)
AGTGeneProduct421543 (Entrez Gene)
AHRGeneProduct373907 (Entrez Gene)
ASIPGeneProduct419147 (Entrez Gene)
BMP1GeneProduct414883 (Entrez Gene)
BMP2GeneProduct378779 (Entrez Gene)
BMP3GeneProduct422581 (Entrez Gene)
BMP4GeneProduct396165 (Entrez Gene)
BSCL2GeneProduct
CDKN1AGeneProduct
CEBPAGeneProduct427549 (Entrez Gene)
CEBPBGeneProduct396185 (Entrez Gene)
CEBPDGeneProduct
CISD1GeneProduct423642 (Entrez Gene)
CNTFRGeneProduct395885 (Entrez Gene)
CREB1GeneProduct395099 (Entrez Gene)
CTNNB1GeneProduct395964 (Entrez Gene)
CUGBP1GeneProduct373923 (Entrez Gene)
CYP26A1GeneProduct408183 (Entrez Gene)
CYP26B1GeneProduct428809 (Entrez Gene)
DDIT3GeneProduct
DFGeneProduct
DLK1GeneProduct423459 (Entrez Gene)
E2F1GeneProduct396142 (Entrez Gene)
E2F4GeneProduct769430 (Entrez Gene)
EBF1GeneProduct395512 (Entrez Gene)
EGR2GeneProduct
EPAS1GeneProduct395596 (Entrez Gene)
FASGeneProduct395274 (Entrez Gene)
FOXC2GeneProduct396039 (Entrez Gene)
FOXO1AGeneProduct374231 (Entrez Gene)
FRZBGeneProduct395545 (Entrez Gene)
FZD1GeneProduct374062 (Entrez Gene)
GADD45AGeneProduct693255 (Entrez Gene)
GADD45BGeneProduct429929 (Entrez Gene)
GATA2GeneProduct416018 (Entrez Gene)
GATA3GeneProduct419106 (Entrez Gene)
GATA4GeneProduct396392 (Entrez Gene)
GDF10GeneProduct423776 (Entrez Gene)
GH1GeneProduct378781 (Entrez Gene)
GTF3AGeneProduct418931 (Entrez Gene)
HIF1AGeneProduct374177 (Entrez Gene)
HMGA1GeneProduct378795 (Entrez Gene)
HNF1AGeneProduct416967 (Entrez Gene)
ID3GeneProduct395281 (Entrez Gene)
IGF1GeneProduct418090 (Entrez Gene)
IL6GeneProduct395337 (Entrez Gene)
IL6STGeneProduct395684 (Entrez Gene)
INSGeneProduct396145 (Entrez Gene)
IRS1GeneProduct429126 (Entrez Gene)
IRS2GeneProduct428017 (Entrez Gene)
IRS3LGeneProduct
IRS4GeneProduct
KLF15GeneProduct427588 (Entrez Gene)
KLF5GeneProduct418818 (Entrez Gene)
KLF6GeneProduct420463 (Entrez Gene)
KLF7GeneProduct429011 (Entrez Gene)
LEPGeneProduct373955 (Entrez Gene)
LIFGeneProduct427718 (Entrez Gene)
LIFRGeneProduct395262 (Entrez Gene)
LIPEGeneProduct
LMNAGeneProduct396224 (Entrez Gene)
LPIN1GeneProduct421945 (Entrez Gene)
LPIN2GeneProduct421059 (Entrez Gene)
LPIN3GeneProduct
LPLGeneProduct396219 (Entrez Gene)
MEF2AGeneProduct395670 (Entrez Gene)
MEF2BGeneProduct
MEF2CGeneProduct769007 (Entrez Gene)
MEF2DGeneProduct769067 (Entrez Gene)
MIFGeneProduct
MIXL1GeneProduct395838 (Entrez Gene)
NCOA1GeneProduct422016 (Entrez Gene)
NCOA2GeneProduct420176 (Entrez Gene)
NCOR1GeneProduct417598 (Entrez Gene)
NCOR2GeneProduct416815 (Entrez Gene)
NDNGeneProduct
NR1H3GeneProduct395221 (Entrez Gene)
NR2F1GeneProduct
NR3C1GeneProduct416343 (Entrez Gene)
NRIP1GeneProduct427966 (Entrez Gene)
OSMGeneProduct
PCK1GeneProduct396458 (Entrez Gene)
PCK2GeneProduct
PLINGeneProduct415487 (Entrez Gene)
PPARAGeneProduct374120 (Entrez Gene)
PPARDGeneProduct395479 (Entrez Gene)
PPARGGeneProduct373928 (Entrez Gene)
PPARGC1AGeneProduct422815 (Entrez Gene)
PRLRGeneProduct395660 (Entrez Gene)
PTGISGeneProduct
RARAGeneProduct395213 (Entrez Gene)
RB1GeneProduct386582 (Entrez Gene)
RBL1GeneProduct419126 (Entrez Gene)
RBL2GeneProduct415721 (Entrez Gene)
RCJMB04_17i9GeneProduct424044 (Entrez Gene)
RCJMB04_2d20GeneProduct419416 (Entrez Gene)
RCJMB04_6p13GeneProduct417707 (Entrez Gene)
RCJMB04_8n15GeneProduct425033 (Entrez Gene)
RETNGeneProduct
RORAGeneProduct415377 (Entrez Gene)
RXRAGeneProduct417143 (Entrez Gene)
RXRGGeneProduct396231 (Entrez Gene)
SCDGeneProduct395706 (Entrez Gene)
SERPINE1GeneProduct
SFRP4GeneProduct420732 (Entrez Gene)
SLC2A4GeneProduct
SMAD3GeneProduct395132 (Entrez Gene)
SOCS1GeneProduct416630 (Entrez Gene)
SOCS3GeneProduct395299 (Entrez Gene)
SP1GeneProduct395303 (Entrez Gene)
SPOCK1GeneProduct416304 (Entrez Gene)
SREBF1GeneProduct373915 (Entrez Gene)
STAT2GeneProduct
STAT3GeneProduct420027 (Entrez Gene)
STAT5AGeneProduct
STAT5BGeneProduct395556 (Entrez Gene)
STAT6GeneProduct
TGFB1GeneProduct
TNFGeneProduct
TRIB3GeneProduct
TWIST1GeneProduct395491 (Entrez Gene)
UCP1GeneProduct
WNT1GeneProduct
WNT10BGeneProduct
WNT5BGeneProduct418154 (Entrez Gene)
WWTR1GeneProduct
ZMPSTE24GeneProduct419572 (Entrez Gene)

Annotated Interactions

No annotated interactions
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