1ThLymphocyte ActivatedKiller Cells (LAK)MHC IIB CellEosEosTCRThFibroblastsHypothalamus(fever)B CellMacrophageTcB Cell Hematopoietic Stem CellMast CellEndothelial CellsB CellHematopoiesisT-helperNeutrophilantigenTcT-helperClonal expansion of T cellsPlasma CellEosTcThNK cellantibodiesIL4IL2HLA-DRAIL13IL15IL1ATGFB1CD4IL10TGFB1CSF1IL3IL1BIL3CSF2IFN1@IL5IL1BIL1ACSF3IL10IL4IL4IL5IL3IL15IFNB1TGFB1IFNGIL2IL1BIL2IL10IL1AHLA-DRB1CSF2IL6IL12BIL1ACXCL1IL4TNFIFNGIFN1@IL1BTNFIL13IL11IL15TRACXCL2IL4IL2 Inflammatory ResponseTNFTNFPDGFATNFIL6IL10TNFIL1ATNFIL7IL6IL12BIL2IFNGIL6TRBIL6IL3IL1BIL2IL2IL12