1*Cytosol**Synaptic cleft*Pyruvate from glycolysisAcetylcholinePDHA1PDHA2ACHECHATCholinePhosphatidylethanolamineGlycerophosphocholinePhosphatidylcholinePCYT1ACholinePEMTCHKACytidine diphosphate cholineAcetateAcetyl CoAPhosphorylcholine