G13 Signaling Pathway (Rattus norvegicus)

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1Disassembly of ActinMembrane RufflingActin ReorganizationCell-Cell AdhesionStress FiberDisappearanceActin PolymerizationFilopodia FormationCytokinesisActin Polymerization13Anti-ApoptoticActivated Rho AContraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionGMk1WaslRhpn2Cyfip1Pip4k2aCFL1Limk1Rock2AABR07013776.1AABR07037536.1Iqgap2Myl1Map3k4Cdc42Pik3cdArhgdibArhgef1Gna13Pkn1ARHGDIGSh3rf1Diaph1Rac1Rock1Rps6kb1Iqgap1Pak3Cfl2CitWasPik3r2Tnk2MybphPpp1cbRtknMapk10LOC100910021Rhoa


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyMapper 
This pathway was inferred from Homo sapiens pathway WP524 (r95116) with a 94.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
95754view14:07, 19 January 2018MkutmonHomology conversion update
72030view13:02, 24 October 2013Mkutmonfixed unconnected lines
69447view19:06, 8 July 2013MaintBotUpdated to 2013 gpml schema
67277view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
41775view02:42, 2 March 2011MaintBotRemoved redundant pathway information and comments
35415view10:32, 12 February 2010Thomasfixed sra1 annotation
35414view10:30, 12 February 2010Thomasremoved braces, fixed connection
35412view10:26, 12 February 2010ThomasModified description
35410view10:26, 12 February 2010Thomasadded literature
34142view19:33, 9 December 2009MaintBotAutomatic update of empty xrefs
32453view17:23, 15 August 2009MaintBotFixed text labels
32134view13:56, 14 August 2009MaintBotFixed group labels
31471view21:19, 13 August 2009MaintBotFixed text labels
31004view01:02, 30 July 2009MaintBotConverted from Homo sapiens
21772view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:G13 Signaling Pathway]] moved to [[Pathway:WP520]]: Moved to stable identifier
8068view13:46, 7 January 2008MaintBot[[Pathway:Rat:G13 Signaling Pathway]] moved to [[Pathway:Rattus norvegicus:G13 Signaling Pathway]]: Renaming species
7656view16:07, 18 December 2007MaintBotfixed category names
7231view12:41, 4 November 2007MaintBotAdded categories to GPML
19465view22:20, 22 May 2007M.Ramirezgpml file for [[Rat:G13_Signaling_Pathway]]
6543view22:20, 22 May 2007A.Chowgpml file for [[Rat:G13_Signaling_Pathway]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AABR07013776.1GeneProductENSRNOG00000048082 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:801
AABR07037536.1GeneProductENSRNOG00000056810 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5290
ARHGDIGGeneProductNo homologues found for original id L:398
ArhgdibGeneProductENSRNOG00000005809 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:397
Arhgef1GeneProductENSRNOG00000020130 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9138
CFL1GeneProductNo homologues found for original id L:1072
Cdc42GeneProductENSRNOG00000013536 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:998
Cfl2GeneProductENSRNOG00000045892 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1073
CitGeneProductENSRNOG00000001143 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:11113
Cyfip1GeneProductENSRNOG00000011945 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:23191
Diaph1GeneProductENSRNOG00000019688 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:1729
Gna13GeneProductENSRNOG00000036745 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10672
Iqgap1GeneProductENSRNOG00000012002 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:8826
Iqgap2GeneProductENSRNOG00000025406 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10788
LOC100910021GeneProductENSRNOG00000023622 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5291
Limk1GeneProductENSRNOG00000001470 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:3984
Map3k4GeneProductENSRNOG00000017419 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4216
Mapk10GeneProductENSRNOG00000002079 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5602
Mk1GeneProductENSRNOG00000019657 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5216
MybphGeneProductENSRNOG00000003336 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4608
Myl1GeneProductENSRNOG00000013262 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:4632
Pak3GeneProductENSRNOG00000004676 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5063
Pik3cdGeneProductENSRNOG00000016846 (Ensembl)
  • P42338
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5293
Pik3r2GeneProductENSRNOG00000019228 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5296
Pip4k2aGeneProductENSRNOG00000016670 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5305
Pkn1GeneProductENSRNOG00000004131 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5585
Ppp1cbGeneProductENSRNOG00000004612 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5500
Rac1GeneProductENSRNOG00000001068 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:5879
RhoaGeneProductENSRNOG00000050519 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:387
Rhpn2GeneProductENSRNOG00000011885 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:85415
Rock1GeneProductENSRNOG00000031092 (Ensembl)
  • S69211
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6093
Rock2GeneProductENSRNOG00000004496 (Ensembl)
  • BAA31594
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:9475
Rps6kb1GeneProductENSRNOG00000003919 (Ensembl)
  • A41687
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6198
RtknGeneProductENSRNOG00000059679 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:6242
Sh3rf1GeneProductENSRNOG00000010358 (Ensembl)
  • Posh
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:57630
Tnk2GeneProductENSRNOG00000001769 (Ensembl)
  • S33596
  • Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:10188
WasGeneProductENSRNOG00000031058 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:7454
WaslGeneProductENSRNOG00000006975 (Ensembl) Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = L:8976

Annotated Interactions

No annotated interactions
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