Response to acute ibuprofen exposure (Daphnia magna)

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1Starch andsucrosemetabolismCarbohydratemetabolism1,2 DiacylglycerolGlyPamyAGlycolysisFructose andmannosemetabolismEnoMANALipidmetabolismGlycerolipidmetabolismLipFatty acidmetabolismACSGlycerophospholipidmetabolismCTPPhospahtidylcholineGPXEicosanoidmetabolismCOXLtb4dhACSPPAR signallingpathwayFABP3RXRVDAC2Calcium signallingpathwaySignaltransduction


Description

Pathway that describes the biological response found in Daphnia magna after exposure to ibuprofen. Warning: Gene identifiers are based on the full names in the Additional File 1 as the article does not contains accession numbers for the Daphnia genes. Search in Ensembl returned on several occasions multiple potential hits where one was randomly selected.

Quality Tags

Ontology Terms

 

Bibliography

  1. Heckmann LH, Sibly RM, Connon R, Hooper HL, Hutchinson TH, Maund SJ, Hill CJ, Bouetard A, Callaghan A; ''Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna.''; Genome Biol, 2008 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
122821view16:32, 21 May 2022EgonwModified description
122820view16:29, 21 May 2022EgonwMore gene identifiers
122819view14:01, 21 May 2022MaintBotAdded the first three gene variants (using Additional file 1)
116342view12:46, 2 May 2021L DupuisConnected lines
116164view15:45, 14 April 2021EgonwMore content
116124view06:36, 13 April 2021EgonwAdded a first identifier
116123view06:35, 13 April 2021EgonwAnother bit of the pathway
116109view14:48, 12 April 2021EgonwOntology Term : 'drug pathway' added !
116108view14:48, 12 April 2021EgonwModified description
116104view14:44, 12 April 2021EgonwHandset the species
116103view14:42, 12 April 2021EgonwNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1,2 DiacylglycerolMetaboliteCHEBI:49172 (ChEBI)
ACSGeneProductAPZ42_024578 (Ensembl)
COXGeneProduct
CTPGeneProduct
EnoGeneProductAPZ42_018388 (Ensembl)
FABP3GeneProductAPZ42_014858 (Ensembl)
GPXGeneProductAPZ42_030648 (Ensembl)
GlyPGeneProductAPZ42_020436 (Ensembl)
LipGeneProductAPZ42_029151 (Ensembl)
Ltb4dhGeneProduct
MANAGeneProductAPZ42_024669 (Ensembl)
PhospahtidylcholineMetaboliteCHEBI:64482 (ChEBI)
RXRGeneProduct
VDAC2GeneProductAPZ42_018910 (Ensembl)
amyAGeneProductAPZ42_021009 (Ensembl)

Annotated Interactions

No annotated interactions

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