Overview of perturbations to host-cell autophagy, induced by distinct proteins of SARS-CoV-2 (Homo sapiens)

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Accumulation of autophagy receptors AutophagosomeCALCOCO2ATG7MLST8PKMATG5SQSTM1ORF3ORF3TSC2RPTORAKTS1VPS41AKT1DEPTORRPS6ATG3P70S6KORF3MAP1LC3BVPS33ATAX1BP1ATG9ANSP6HOPS COMPLEXAMPKULK1RAB7ANRB1MTORGSK3LARP1SNAREsATG16LVPS36VPS11OPTNATG13VPS18VPS16FIP200GABARAPL2ATG12TSC2RHEBATG4S18K149S203S240S738S202K143T1162S735T525S238LysosomeAutolysosomeFusionLate endosome


Description

Overview of

perturbations to host-cell autophagy, induced by distinct proteins of SARS-CoV-2, derived from the network diffusion model and overlaid with the changes in protein levels, ubiquitination and

phosphorylation induced by SARS-CoV-2 infection.

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History

CompareRevisionActionTimeUserComment
110905view10:51, 19 June 2020Rex D A BNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProductAKT1
AKTS1GeneProductAKTS1
AMPKGeneProductAMPK
ATG12GeneProductATG12
ATG13GeneProductATG13
ATG16LGeneProductATG16L
ATG3GeneProductATG3
ATG4GeneProductATG4
ATG5GeneProductATG5
ATG7GeneProductATG7
ATG9AGeneProductATG9A
CALCOCO2GeneProductCALCOCO2
DEPTORGeneProductDEPTOR
FIP200GeneProductFIP200
GABARAPL2GeneProductGABARAPL2
GSK3GeneProductGSK3
HOPS COMPLEXGeneProductHOPS COMPLEX
LARP1GeneProductLARP1
MAP1LC3BGeneProductMAP1LC3B
MLST8GeneProductMLST8
MTORGeneProductMTOR
NRB1GeneProductNRB1
NSP6GeneProductNSP6
OPTNGeneProductOPTN
ORF3GeneProductORF3
P70S6KGeneProductP70S6K
PKMGeneProductPKM
RAB7AGeneProductRAB7A
RHEBGeneProductRHEB
RPS6GeneProductRPS6
RPTORGeneProductRPTOR
SNAREsGeneProductSNAREs
SQSTM1GeneProductSQSTM1
TAX1BP1GeneProductTAX1BP1
TSC2GeneProductTSC2
ULK1GeneProductULK1
VPS11GeneProductVPS11
VPS16GeneProductVPS16
VPS18GeneProductVPS18
VPS33AGeneProductVPS33A
VPS36GeneProductVPS36
VPS41GeneProductVPS41

Annotated Interactions

No annotated interactions

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