Mitochondrial CI inhibition (Homo sapiens)

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Cell deathLiver injuryMitochondrial dysfunctionBrain injuryKidney injuryKidneyLiverDecreased Na/K ATPase activityBrainChemical induced Fanconi syndromeDeguelinIncreased ROSAutophagyNeuroinflammationDecreased proximal tubule vectorial transportNecrosisUPRInhibition of mitochondrial Complex IDegeneration of DA neurons of nigrostratial pathwayDecreased mitochondrial oxidative phosphorylationParkinsonian motor deficitsFerroptosisRotenoneApoptosisImpaired proteostasis


Description

AOP for C1 inhibition

Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
110993view17:50, 25 June 2020Marvin M2Modified title
110831view12:58, 11 June 2020AnnabayaEdit pathway node shapes
110381view15:34, 8 May 2020AnnabayaOntology Term : 'immune response pathway' added !
110378view15:29, 8 May 2020AnnabayaAdd pathway identifiers
110314view22:12, 3 May 2020Marvin M2Connected unconnected lines
110303view06:37, 3 May 2020EgonwReplaced a secondary ChEBI identifiers with a primary identifier.
110271view13:53, 1 May 2020AnnabayaModified title
110270view13:51, 1 May 2020AnnabayaNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ApoptosisPathwayWP1772 (WikiPathways)
AutophagyPathwayWP4923 (WikiPathways)
Decreased mitochondrial oxidative phosphorylationPathwayWP111 (WikiPathways)
Decreased proximal tubule vectorial transportPathwayWP4917 (WikiPathways)
Degeneration of DA neurons of nigrostratial pathwayPathwayWP2855 (WikiPathways)
DeguelinMetaboliteCHEBI:4357 (ChEBI)
FerroptosisPathwayWP4313 (WikiPathways)
Impaired proteostasisPathwayWP4918 (WikiPathways)
Increased ROSPathwayWP3941 (WikiPathways)
Inhibition of mitochondrial Complex IPathwayWP4324 (WikiPathways)
NecrosisPathwayWP3383 (WikiPathways)
NeuroinflammationPathwayWP4919 (WikiPathways)
Parkinsonian motor deficitsPathwayWP2371 (WikiPathways)
RotenoneMetaboliteCHEBI:28201 (ChEBI)
UPRPathwayWP4925 (WikiPathways)

Annotated Interactions

No annotated interactions

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