Proteasome Degradation (Caenorhabditis elegans)

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Alpha subunitsCytosolic ProteinsUbiquitin/ProteinOxidatively DamagedAMP Ubiquitin/E1 ComplexLid subunitsPresentation by MHC class 120S ComplexDegrades only PeptidesATPUbiquitin/E2 ComplexIntact ProteinsBeta subunitsCatalytic Core (p45)E3/ProteinProteasome 26 SProteins to be DegradedProteasome 20S(PA700) (ATP dependent)p45 ATPase SubunitUnfolds and DegradesActivators ofendopeptidaseM01A10.3rpn-12pas-7HLA-Hrpn-5C44B7.1UBE1Lrpn-9glycotransferaserpt-1IFNGATPaseHLA-Flet-70PSMD1R08C7.3UBE2D2UBE2D1PSMB9rpn-10pas-5Peptidasepbs-1HLA-Grpn-8HLA-Erpt-3ATPasePSMB4PSMB8PSMD5pas-2Y66D12A.9PSME1rpt-6HLA-CpeptidaseF40G9.1HLA-BUBE2Buba-1PSMB7PSME2pbs-6HLA-Arpn-3rpn-7HIST1H2ABrpn-6pas-1pbs-5rpt-6HLA-Jhis-35pas-4rpn-1NEDD4rpt-4proteasePSMB10ubq-1


Description

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Quality Tags

Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
78051view12:24, 23 November 2014EgonwRemoved database source when no identifier was given.
68456view20:15, 5 July 2013MaintBotUpdated to 2013 gpml schema
67614view11:33, 26 June 2013DdiglesOntology Term : 'ubiquitin/proteasome degradation pathway' added !
40611view19:56, 1 March 2011MaintBotRemoved redundant pathway information and comments
21668view11:32, 14 November 2008MaintBot[[Pathway:Caenorhabditis elegans:Proteasome Degradation]] moved to [[Pathway:WP470]]: Moved to stable identifier
9023view14:14, 7 January 2008MaintBotAdded to category $category
9021view14:14, 7 January 2008NsalomonisUploaded new pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ATPaseGeneProduct172238 (Entrez Gene)
ATPaseGeneProduct178988 (Entrez Gene)
C44B7.1GeneProduct174129 (Entrez Gene)
F40G9.1GeneProduct175187 (Entrez Gene)
HIST1H2ABGeneProduct
HLA-AGeneProduct
HLA-BGeneProduct
HLA-CGeneProduct
HLA-EGeneProduct
HLA-FGeneProduct
HLA-GGeneProduct
HLA-HGeneProduct
HLA-JGeneProduct
IFNGGeneProduct
M01A10.3GeneProduct172208 (Entrez Gene)
NEDD4GeneProduct
PSMB10GeneProduct
PSMB4GeneProduct
PSMB7GeneProduct
PSMB8GeneProduct
PSMB9GeneProduct
PSMD1GeneProduct
PSMD5GeneProduct
PSME1GeneProduct
PSME2GeneProduct
PeptidaseGeneProduct173858 (Entrez Gene)
R08C7.3GeneProduct177212 (Entrez Gene)
UBE1LGeneProduct
UBE2BGeneProduct
UBE2D1GeneProduct
UBE2D2GeneProduct
Y66D12A.9GeneProduct176588 (Entrez Gene)
endopeptidaseGeneProduct172139 (Entrez Gene)
glycotransferaseGeneProduct177456 (Entrez Gene)
his-35GeneProduct179339 (Entrez Gene)
let-70GeneProduct178006 (Entrez Gene)
pas-1GeneProduct179941 (Entrez Gene)
pas-2GeneProduct179493 (Entrez Gene)
pas-4GeneProduct172679 (Entrez Gene)
pas-5GeneProduct172942 (Entrez Gene)
pas-7GeneProduct174571 (Entrez Gene)
pbs-1GeneProduct176978 (Entrez Gene) U13393
pbs-5GeneProduct173334 (Entrez Gene)
pbs-6GeneProduct176161 (Entrez Gene)
peptidaseGeneProduct171975 (Entrez Gene)
proteaseGeneProduct178943 (Entrez Gene)
rpn-10GeneProduct172977 (Entrez Gene)
rpn-1GeneProduct177455 (Entrez Gene)
rpn-12GeneProduct174786 (Entrez Gene)
rpn-3GeneProduct176196 (Entrez Gene)
rpn-5GeneProduct173807 (Entrez Gene)
rpn-6GeneProduct175972 (Entrez Gene)
rpn-7GeneProduct177753 (Entrez Gene)
rpn-8GeneProduct172009 (Entrez Gene)
rpn-9GeneProduct174715 (Entrez Gene)
rpt-1GeneProduct179641 (Entrez Gene)
rpt-3GeneProduct175925 (Entrez Gene) PRS6_HUMAN
rpt-4GeneProduct173384 (Entrez Gene)
rpt-6GeneProduct176661 (Entrez Gene) PRS6_HUMAN
uba-1GeneProduct177855 (Entrez Gene)
ubq-1GeneProduct175840 (Entrez Gene)

Annotated Interactions

No annotated interactions

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