7641High fat dietATP3-keto-sphinganine3Ppap2aCerkSgpp1Asah1Palmitoyl-CoA3Sgms1Sphk2Sgpl1UgcgSerine3HexadecanalSptlc1Sphk1Degs1KdsrSptlc2Ethanolamine-phosphateH2OSphingosineSphinganine3Sphinganine-1-phosphateCerS4CerS5CerS61, 2, 5C16 CerP5C16DH CerPC16 SMC16 GlcCerC16DH SMC16DH GlcCerC16 GalCerC16DH GalCerSmpd1Degs2Sgms2Sphingosine-1-phosphate1-HexadecenalPpap2bPpap2cUgt8aCoA(16:0)CoA(18:0)CoA(20:0)CoA(22:0)CoA(24:0)CoA(24:1)C16DH-CerCerS15CerS4Cers25CoA(26:0)CoA(26:1)Cers3ADPSgpp2Sphk2Sphk1Sgpl1CerS45Cers2CerS45CoA(14:0)C14DH-CeramideCerS5CerS655C16 Cer3CerkUgcgSmpd1Sgms1Sgms2Ugt8aC18 CerPC18DH CerPC18 SMC18 GlcCerC18DH SMC18DH GlcCerC18 GalCerC18DH GalCerC18DH-CerC18 CerC20 CerPC20DH CerPC20 SMC20 GlcCerC20DH SMC20DH GlcCerC20 GalCerC20DH GalCerC20DH-CerC20 CerC22 CerPC22DH CerPC22 SMC22 GlcCerC22DH SMC22DH GlcCerC22 GalCerC22DH GalCerC22DH-CerC22 CerC24 CerPC24DH CerPC24 SMC24 GlcCerC24DH SMC24DH GlcCerC24 GalCerC24DH GalCerC24DH-CerC24 CerC24:1 CerPC24:1DH CerPC24:1 SMC24:1 GlcCerC24:1DH SMC24:1DH GlcCerC24:1 GalCerC24:1DH GalCerC24:1DH-CerC24:1 CerCers3C26:1 CerPC26:1DH CerPC26:1 SMC26:1 GlcCerC26:1DH SMC26:1DH GlcCerC26:1 GalCerC26:1DH GalCerC26:1DH-CerC26:1 CerC26 CerPC26DH CerPC26 SMC26 GlcCerC26DH SMC26DH GlcCerC26 GalCerC26DH GalCerC26DH-CerC26 CerEthanolamine-phosphate