IL-5 Signaling Pathway (Rattus norvegicus)

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PM->NUMolecular associationReceptorAccession Number: NetPath 17Enzyme complexTranslocationUbiquitinationGolgi apparatusAutophosphorylationAcetylationNucleusProteins in a complex interactionProteolytic cleavageGene SymbolDEndosomeEND(Protein-protein interaction)CYDPM->NUSumoylationDDInhibitionMethylationDCY->NUCytoplasmGODPM->NUPMERActivationPlasma membraneCY->MTDMTDDReaction through unknown mechanisms/moleculesDExtracellularDeacetylationDeubiquitinationRecruitmentCY->PMCY->NUDDCY->NUMolecule in the pathwayMitochondriaDesumoylationLigandDNUGlycosylationDephosphorylationECDemethylationDControlPalmitoylationDEndoplasmic reticulumDPhosphorylationDRap1gapPik3r1IL2RBYwhazMap2k2Alox5Stat5bStat1Foxo3HckNfkb1Stat5aJak2Mapk3CrklItgb2Shc2Rac1Atf2Cdkn1bIl5Ptpn11Raf1PrkcdPrkcbHcls1Pik3r2Ptpn6Elk1Sox4Ccnd3Gsk3bMapk14Il5raGrb2SykCrklRAPGEF1Ptk2bSdcbpLynStat5aGsk3aIcam1BtkCblAkt1JunCsf2rbNfkb1HrasUnc119Pik3cgSh2b2Dnm2Socs1BaxRps6ka1ICAM3Pla2g4aCtnnb1Mapk9Stat3Pim1PrkcdMapk1Alox5Ctnnb1Alox5apJak1BaxVav1Csf2rbCsf2rbShc1NfkbiaIl5raIl5ItgamKrasStat5b


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 96% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
69358view18:53, 8 July 2013MaintBotUpdated to 2013 gpml schema
67382view10:45, 26 June 2013Christine ChichesterOntology Term : 'interleukin-5 signaling pathway' added !
41671view02:35, 2 March 2011MaintBotRemoved redundant pathway information and comments
34063view19:07, 9 December 2009MaintBotAutomatic update of empty xrefs
31452view21:11, 13 August 2009MaintBotFixed text labels
30917view00:32, 30 July 2009MaintBotConverted from Homo sapiens
20769view11:29, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:IL-5 NetPath 17]] moved to [[Pathway:WP44]]: Moved to stable identifier
8186view13:46, 7 January 2008MaintBot[[Pathway:Rat:IL-5 NetPath 17]] moved to [[Pathway:Rattus norvegicus:IL-5 NetPath 17]]: Renaming species
7713view16:12, 18 December 2007MaintBotfixed category names
7252view12:41, 4 November 2007MaintBotAdded categories to GPML
6562view22:20, 22 May 2007A.Pandeygpml file for [[Rat:IL-5_NetPath_17]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1GeneProduct24185 (Entrez Gene)
Alox5GeneProduct25290 (Entrez Gene)
Alox5apGeneProduct29624 (Entrez Gene)
Atf2GeneProduct81647 (Entrez Gene)
BaxGeneProduct24887 (Entrez Gene)
BtkGeneProduct367901 (Entrez Gene)
CblGeneProduct500985 (Entrez Gene)
Ccnd3GeneProduct25193 (Entrez Gene)
Cdkn1bGeneProduct83571 (Entrez Gene)
CrklGeneProduct287942 (Entrez Gene)
Csf2rbGeneProduct171081 (Entrez Gene)
Ctnnb1GeneProduct84353 (Entrez Gene)
Dnm2GeneProduct25751 (Entrez Gene)
Elk1GeneProduct314436 (Entrez Gene)
Foxo3GeneProduct294515 (Entrez Gene)
Grb2GeneProduct81504 (Entrez Gene)
Gsk3aGeneProduct50686 (Entrez Gene)
Gsk3bGeneProduct84027 (Entrez Gene)
HckGeneProduct25734 (Entrez Gene)
Hcls1GeneProduct288077 (Entrez Gene)
HrasGeneProduct293621 (Entrez Gene)
ICAM3GeneProduct
IL2RBGeneProduct25746 (Entrez Gene)
Icam1GeneProduct25464 (Entrez Gene)
Il5GeneProduct24497 (Entrez Gene)
Il5raGeneProduct114103 (Entrez Gene)
ItgamGeneProduct25021 (Entrez Gene)
Itgb2GeneProduct309684 (Entrez Gene)
Jak1GeneProduct84598 (Entrez Gene)
Jak2GeneProduct24514 (Entrez Gene)
JunGeneProduct24516 (Entrez Gene)
KrasGeneProduct24525 (Entrez Gene)
LynGeneProduct81515 (Entrez Gene)
Map2k2GeneProduct58960 (Entrez Gene)
Mapk1GeneProduct116590 (Entrez Gene)
Mapk14GeneProduct81649 (Entrez Gene)
Mapk3GeneProduct50689 (Entrez Gene)
Mapk9GeneProduct50658 (Entrez Gene)
Nfkb1GeneProduct81736 (Entrez Gene)
NfkbiaGeneProduct25493 (Entrez Gene)
Pik3cgGeneProduct298947 (Entrez Gene)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct29741 (Entrez Gene)
Pim1GeneProduct24649 (Entrez Gene)
Pla2g4aGeneProduct24653 (Entrez Gene)
PrkcbGeneProduct25023 (Entrez Gene)
PrkcdGeneProduct170538 (Entrez Gene)
Ptk2bGeneProduct50646 (Entrez Gene)
Ptpn11GeneProduct25622 (Entrez Gene)
Ptpn6GeneProduct116689 (Entrez Gene)
RAPGEF1GeneProduct63881 (Entrez Gene)
Rac1GeneProduct363875 (Entrez Gene)
Raf1GeneProduct24703 (Entrez Gene)
Rap1gapGeneProduct313644 (Entrez Gene)
Rps6ka1GeneProduct81771 (Entrez Gene)
SdcbpGeneProduct83841 (Entrez Gene)
Sh2b2GeneProduct114203 (Entrez Gene)
Shc1GeneProduct85385 (Entrez Gene)
Shc2GeneProduct314612 (Entrez Gene)
Socs1GeneProduct252971 (Entrez Gene)
Sox4GeneProduct364712 (Entrez Gene)
Stat1GeneProduct25124 (Entrez Gene)
Stat3GeneProduct25125 (Entrez Gene)
Stat5aGeneProduct24918 (Entrez Gene)
Stat5bGeneProduct25126 (Entrez Gene)
SykGeneProduct25155 (Entrez Gene)
Unc119GeneProduct29402 (Entrez Gene)
Vav1GeneProduct25156 (Entrez Gene)
YwhazGeneProduct25578 (Entrez Gene)

Annotated Interactions

No annotated interactions
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