Glycolysis and Gluconeogenesis - for workshop (Homo sapiens)

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1GluconeogenesisGlycolysisGlucoseALDOCENO1LDHBLactatePyruvateGlycogen metabolismLDHCMPC2PKM2ALDOAGlucoseFBP1Fructose-1,6BPPFKLPGAM2HK2Glyceraldehyde 3P1,3BP-GlycerateSLC2A3OxaloacetatePFKPSLC2A4PCK1PGK1PyruvateLDHAL6BFBP2Glucose-6PTriglyceride synthesisGAPDHPentose Phosphate PathwayFructose 6PMPC1PKM2PFKMPGK2GOT1LDHADihydroxyacetone-PPKLRHK3SLC2A5ALDOBGCKPGAM1MalateG6PCMDH1Aspartate3P-GlycerateHK1TPI1ENO3ENO22P-GlycerateSLC2A2P-enolpyruvateSLC2A1Glucose-6P (open)PGIFructose 6P (open)GPI


Description

This pathway is intended to use in a workshop setting, and represents a subset of the full "glycolysis and gluconeogenesis" pathway. Do not delete.

Quality Tags

Ontology Terms

 

Bibliography

  1. Bricker DK, Taylor EB, Schell JC, Orsak T, Boutron A, Chen YC, Cox JE, Cardon CM, Van Vranken JG, Dephoure N, Redin C, Boudina S, Gygi SP, Brivet M, Thummel CS, Rutter J; ''A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.''; Science, 2012 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
107170view14:25, 17 September 2019MaintBotChEBI identifier normalization
106800view13:28, 17 September 2019MaintBotHMDB identifier normalization
98730view23:31, 2 October 2018Khanspersupdated complexes
98728view23:14, 2 October 2018Khanspersfine tuning
98726view20:22, 2 October 2018KhanspersModified description
98725view20:22, 2 October 2018KhanspersModified description
98724view20:21, 2 October 2018KhanspersModified title
98723view20:21, 2 October 2018KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,3BP-GlycerateMetaboliteHMDB0001270 (HMDB)
2P-GlycerateMetaboliteHMDB0000362 (HMDB)
3P-GlycerateMetaboliteHMDB0000807 (HMDB)
ALDOAGeneProduct226 (Entrez Gene)
ALDOBGeneProduct229 (Entrez Gene)
ALDOCGeneProduct230 (Entrez Gene)
AspartateMetaboliteHMDB0000191 (HMDB)
Dihydroxyacetone-PMetaboliteHMDB0001473 (HMDB)
ENO1GeneProduct2023 (Entrez Gene)
ENO2GeneProduct2026 (Entrez Gene)
ENO3GeneProduct2027 (Entrez Gene)
FBP1GeneProduct2203 (Entrez Gene)
FBP2GeneProduct8789 (Entrez Gene)
Fructose 6P (open)MetaboliteCHEBI:57579 (ChEBI) fructose-6-phosphate (2-) open form
Fructose 6PMetaboliteCHEBI:61527 (ChEBI)
Fructose-1,6BPMetaboliteHMDB0001058 (HMDB)
G6PCGeneProduct2538 (Entrez Gene) Not present in brain and muscle, so those organs can not produce their own glucose in the gluconeogenesis pathway
GAPDHGeneProductENSG00000111640 (Ensembl)
GCKGeneProduct2645 (Entrez Gene) Gck is mainly active in liver
GOT1GeneProduct2805 (Entrez Gene)
GPIGeneProduct2821 (Entrez Gene) glucose-6-phosphate isomerase
Glucose-6P (open)MetaboliteCHEBI:57584 (ChEBI) D-Glucose-6-Phosphate (2-) open form
Glucose-6PMetaboliteCHEBI:75052 (ChEBI) Glucose-6-Phosphate (2-)
GlucoseMetaboliteHMDB0000122 (HMDB)
Glyceraldehyde 3PMetaboliteHMDB0001112 (HMDB)
Glycogen metabolismPathwayWP500 (WikiPathways)
HK1GeneProduct3098 (Entrez Gene)
HK2GeneProduct3099 (Entrez Gene)
HK3GeneProduct3101 (Entrez Gene)
LDHAGeneProduct3939 (Entrez Gene)
LDHAL6BGeneProduct92483 (Entrez Gene)
LDHBGeneProduct3945 (Entrez Gene)
LDHCGeneProduct3948 (Entrez Gene)
LactateMetaboliteHMDB0000190 (HMDB)
MDH1GeneProduct4190 (Entrez Gene)
MPC1GeneProduct51660 (Entrez Gene)
MPC2GeneProduct25874 (Entrez Gene)
MalateMetaboliteHMDB0000744 (HMDB)
OxaloacetateMetaboliteHMDB0000223 (HMDB)
P-enolpyruvateMetaboliteHMDB0000263 (HMDB)
PCK1GeneProduct5105 (Entrez Gene)
PFKLGeneProduct5211 (Entrez Gene)
PFKMGeneProduct5213 (Entrez Gene)
PFKPGeneProduct5214 (Entrez Gene)
PGAM1GeneProduct5223 (Entrez Gene)
PGAM2GeneProduct5224 (Entrez Gene)
PGIGeneProduct5.3.1.9 (Enzyme Nomenclature) phosphoglucose isomerase (PGI)
PGK1GeneProduct5230 (Entrez Gene)
PGK2GeneProduct5232 (Entrez Gene)
PKLRGeneProduct5313 (Entrez Gene)
PKM2GeneProduct5315 (Entrez Gene)
Pentose Phosphate PathwayPathwayWP134 (WikiPathways)
PyruvateMetaboliteHMDB0000243 (HMDB)
SLC2A1GeneProduct6513 (Entrez Gene)
SLC2A2GeneProduct6514 (Entrez Gene)
SLC2A3GeneProduct6515 (Entrez Gene)
SLC2A4GeneProduct6517 (Entrez Gene)
SLC2A5GeneProduct6518 (Entrez Gene)
TPI1GeneProduct7167 (Entrez Gene)
Triglyceride synthesisPathwayWP325 (WikiPathways)

Annotated Interactions

No annotated interactions

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