Sphingolipid Metabolism (Mus musculus)

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UgcgSphk2Ppap2aSgpl1Degs1Sphk1Ethanolamine-phosphateAsah1SphingosineSgms1KdsrHexadecanalSptlc2Palmitoyl-CoACerk3-keto-sphinganineSerineSptlc1SphinganineSphinganine-1-phosphateDH-CeramideCerS4CerS5CerS6CeramideCer-1-PDH-Cer-1-PSMGlc-CerDH-SMDH-Glc-CerGal-CerDH-Gal-CerSmpd1Degs2Sgms2Sphingosine-1-phosphate1-HexadecenalPpap2bPpap2cCoA(16:0)Ugt8aCoA(18:0)CoA(20:0)CoA(22:0)CoA(24:0)CoA(24:1)CoA(16:0)CoA(18:0)CoA(20:0)CoA(22:0)CoA(24:0)CoA(24:1)DH-CeramideDH-CeramideDH-CeramideDH-CeramideCerS1CerS4Cers2CoA(26:0)CoA(26:1)DH-CeramideCers3CoA(26:0)CoA(26:1)


Description

This pathway is inspired by the Lipidmaps>Sphingolipids pathway [1].

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
98562view13:24, 17 September 2018DeSlChanged layout slightly, to avoid overlapping interactions.
98561view13:21, 17 September 2018DeSlModified description
98560view13:07, 17 September 2018DeSlChanged layout slightly.
98559view13:05, 17 September 2018DeSlAdded specific proteins for different CoA-tail reactions.
98558view12:31, 17 September 2018DeSlAdded database for Ppap2c.
98557view12:27, 17 September 2018DeSlNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1-HexadecenalMetaboliteLMFA06000088 (LIPID MAPS)
3-keto-sphinganineMetaboliteLMSP01020002 (LIPID MAPS)
Asah1GeneProduct
Cer-1-PMetaboliteLMSP02050000 (LIPID MAPS)
CerS1GeneProductP27545 (Uniprot-TrEMBL)
CerS4GeneProduct67260 (Entrez Gene)
CerS5GeneProduct67260 (Entrez Gene)
CerS6GeneProduct241447 (Entrez Gene)
CeramideMetaboliteLMSP02010000 (LIPID MAPS)
CerkGeneProduct223753 (Entrez Gene)
Cers2GeneProduct76893 (Entrez Gene)
Cers3GeneProductQ1A3B0 (Uniprot-TrEMBL)
CoA(16:0)Metabolite
CoA(18:0)Metabolite
CoA(20:0)Metabolite
CoA(22:0)Metabolite
CoA(24:0)Metabolite
CoA(24:1)Metabolite
CoA(26:0)Metabolite
CoA(26:1)Metabolite
DH-Cer-1-PMetaboliteLMSP020500A0 (LIPID MAPS)
DH-CeramideMetaboliteLMSP02020000 (LIPID MAPS)
DH-Gal-CerMetabolite
DH-Glc-CerMetabolite
DH-SMMetaboliteLMSP030100A0 (LIPID MAPS)
Degs1GeneProduct13244 (Entrez Gene)
Degs2GeneProduct70059 (Entrez Gene)
Ethanolamine-phosphateMetabolite1015 (PubChem-compound)
Gal-CerMetaboliteLMSP0501AC00 (LIPID MAPS)
Glc-CerMetaboliteLMSP0501AA00 (LIPID MAPS)
HexadecanalMetaboliteLMFA06000088 (LIPID MAPS)
KdsrGeneProduct70750 (Entrez Gene)
Palmitoyl-CoAMetaboliteLMFA07050360 (LIPID MAPS) aka CoA(16:0)
Ppap2aGeneProduct19012 (Entrez Gene)
Ppap2bGeneProduct67916 (Entrez Gene)
Ppap2cGeneProduct50784 (NCBI Protein)
SMMetaboliteLMSP03010000 (LIPID MAPS)
SerineMetabolite5951 (PubChem-compound)
Sgms1GeneProduct208449 (Entrez Gene)
Sgms2GeneProduct74442 (Entrez Gene)
Sgpl1GeneProduct20397 (Entrez Gene)
Smpd1GeneProduct20597 (Entrez Gene)
Sphinganine-1-phosphateMetaboliteLMSP01050002 (LIPID MAPS)
SphinganineMetaboliteLMSP01020001 (LIPID MAPS)
Sphingosine-1-phosphateMetaboliteLMSP01050001 (LIPID MAPS)
SphingosineMetaboliteLMSP01010001 (LIPID MAPS)
Sphk1GeneProduct20698 (Entrez Gene)
Sphk2GeneProduct56632 (Entrez Gene)
Sptlc1GeneProduct268656 (Entrez Gene)
Sptlc2GeneProduct
UgcgGeneProduct22234 (Entrez Gene)
Ugt8aGeneProduct22239 (Entrez Gene)

Annotated Interactions

No annotated interactions

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