ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (Homo sapiens)

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1nucleusCancer Stem CellsEpithelial Mesenchymal TransitionSTAT3 target genesAutocrine signalingloopSTAT3JAK1IL6NFKB1RELAIL11RAlncRNA-ATBIL6STlncSox4MIR21IL11IL6RJAK2JAK3JAK1JAK2JAK3IL6IL11STAT3ZEB1SOX4MIR200AMIR200BMIR200CMIR21SOX4UCA1DILCIL6


Description

This pathway describes the influence of ncRNAs on the STAT3 pathway in hepatocellular carcinoma. The model is based on Fig 4 in Klingenberg et al.

Quality Tags

Ontology Terms

 

Bibliography

  1. Klingenberg M, Matsuda A, Diederichs S, Patel T; ''Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.''; J Hepatol, 2017 PubMed

History

CompareRevisionActionTimeUserComment
98466view19:12, 7 September 2018KhanspersOntology Term : 'altered Jak-Stat signaling pathway' added !
98465view19:12, 7 September 2018KhanspersOntology Term : 'hepatocellular carcinoma' added !
98464view19:11, 7 September 2018KhanspersModified description
98463view19:09, 7 September 2018KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
DILCRna
IL11GeneProductENSG00000095752 (Ensembl)
IL11RAGeneProductENSG00000137070 (Ensembl)
IL6GeneProductENSG00000136244 (Ensembl)
IL6RGeneProductENSG00000160712 (Ensembl)
IL6STGeneProductENSG00000134352 (Ensembl)
JAK1GeneProductENSG00000162434 (Ensembl)
JAK2GeneProductENSG00000096968 (Ensembl)
JAK3GeneProductENSG00000105639 (Ensembl)
MIR200AGeneProductENSG00000207607 (Ensembl)
MIR200BGeneProductENSG00000207730 (Ensembl)
MIR200CGeneProductENSG00000207713 (Ensembl)
MIR21GeneProductENSG00000284190 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
RELAGeneProductENSG00000173039 (Ensembl)
SOX4GeneProductENSG00000124766 (Ensembl)
STAT3GeneProductENSG00000168610 (Ensembl)
UCA1GeneProductENSG00000214049 (Ensembl)
ZEB1GeneProductENSG00000148516 (Ensembl)
lncRNA-ATBRna
lncSox4Rna

Annotated Interactions

No annotated interactions

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