Glycolysis Pathway D (2) (Homo sapiens)

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MitochondrionCytosolPGAM1Triglyceride synthesisLDHBPFKLHK3GlucoseDihydroxyacetone-PPFKMLDHCGAPDHLDHAL6BPFKP2P-GlycerateENO3Fructose-1,6BPENO1EnergyGlycogen metabolismPentose Phosphate PathwayPGK21,3BP-GlycerateGlyceraldehyde 3PFructose 6PENO2Acetyl-CoATCA CycleGlucose-6PP-enolpyruvateHK1PGAM2ALDOB3P-GlycerateLDHAALDOAGCKGAPDHSPGK1PyruvateHK2ALDOCGlucose-6P (open)PGIFructose 6P (open)


Description

Glycolysis is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the ATP and NADH.

Gluconeogenesis is a metabolic pathway that results in the generation of glucose from non-carbohydrate carbon substrates such as pyruvate, lactate, glycerol, glucogenic amino acids, and fatty acids.

Description adapted from Wikipedia.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
107165view14:25, 17 September 2019MaintBotChEBI identifier normalization
106789view13:26, 17 September 2019MaintBotHMDB identifier normalization
97267view03:58, 7 May 2018Ambar21Ontology Term : 'glycolysis pathway' added !
97266view03:57, 7 May 2018Ambar21Modified title
97265view03:57, 7 May 2018Ambar21New pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1,3BP-GlycerateMetaboliteHMDB0001270 (HMDB)
2P-GlycerateMetaboliteHMDB0000362 (HMDB)
3P-GlycerateMetaboliteHMDB0000807 (HMDB)
ALDOAGeneProduct226 (Entrez Gene)
ALDOBGeneProduct229 (Entrez Gene)
ALDOCGeneProduct230 (Entrez Gene)
Acetyl-CoAMetaboliteHMDB0001206 (HMDB)
Dihydroxyacetone-PMetaboliteHMDB0001473 (HMDB)
ENO1GeneProduct2023 (Entrez Gene)
ENO2GeneProduct2026 (Entrez Gene)
ENO3GeneProduct2027 (Entrez Gene)
EnergyMetabolite
Fructose 6P (open)MetaboliteCHEBI:57579 (ChEBI) fructose-6-phosphate (2-) open form
Fructose 6PMetaboliteCHEBI:61527 (ChEBI)
Fructose-1,6BPMetaboliteHMDB0001058 (HMDB)
GAPDHGeneProductENSG00000111640 (Ensembl)
GAPDHSGeneProduct26330 (Entrez Gene)
GCKGeneProduct2645 (Entrez Gene) Gck is mainly active in liver
Glucose-6P (open)MetaboliteCHEBI:57584 (ChEBI) D-Glucose-6-Phosphate (2-) open form
Glucose-6PMetaboliteCHEBI:75052 (ChEBI) Glucose-6-Phosphate (2-)
GlucoseMetaboliteHMDB0000122 (HMDB)
Glyceraldehyde 3PMetaboliteHMDB0001112 (HMDB)
Glycogen metabolismPathwayWP500 (WikiPathways)
HK1GeneProduct3098 (Entrez Gene)
HK2GeneProduct3099 (Entrez Gene)
HK3GeneProduct3101 (Entrez Gene)
LDHAGeneProduct3939 (Entrez Gene)
LDHAL6BGeneProduct92483 (Entrez Gene)
LDHBGeneProduct3945 (Entrez Gene)
LDHCGeneProduct3948 (Entrez Gene)
P-enolpyruvateMetaboliteHMDB0000263 (HMDB)
PFKLGeneProduct5211 (Entrez Gene)
PFKMGeneProduct5213 (Entrez Gene)
PFKPGeneProduct5214 (Entrez Gene)
PGAM1GeneProduct5223 (Entrez Gene)
PGAM2GeneProduct5224 (Entrez Gene)
PGIGeneProduct5.3.1.9 (Enzyme Nomenclature) phosphoglucose isomerase (PGI)
PGK1GeneProduct5230 (Entrez Gene)
PGK2GeneProduct5232 (Entrez Gene)
Pentose Phosphate PathwayPathwayWP134 (WikiPathways)
PyruvateMetaboliteHMDB0000243 (HMDB)
TCA CyclePathwayWP78 (WikiPathways)
Triglyceride synthesisPathwayWP325 (WikiPathways)

Annotated Interactions

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