Superpathway of Histidine, Purine, and Pyrimidine (Saccharomyces cerevisiae)

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H2OAMPphosphoribulosylformimino-AICAR-PH+phosphoribosyl-AMPH2Ophosphoribosyl-formamido-carboxamidereduced flavodoxindihydroorotateH2OCO2UMPoxidized flavodoxinorotateCTPH2OH+sucinocarboxamide)-5-aminoimidazolefumerate5’-phosphoribosyl-4-(N-THFHCO3AMPH2ONADNADacceptorH2OUTPH+UDPL-aspartate2-oxoglutarateH2OH2OH2OH2O5’-phosphoribosyl-5-aminoimidazoleAMPCO2IMPorotidine-5’-phosphatedeoxy-GTPreduced thioredoxinH2OL-aspartateH2O5-phosphoribosyl-n-formylglycineamidineimidazole acetol-phosphateNADNH3carbamoyl-L-aspartatephosphoribosyl-carboxy-aminoimidazole5-phosphoribosylamine5-phospho-ribosyl-glycineamideD-erythro-imidazole-glycerol-phosphateTHFphosphoribosyl-ATPH2Ocarbamoyl-phosphatereduced acceptorH2OH2OphosphoribosylformiminoAICAR-phosphatehistidinolhistidinal5’-phosphoribosyl-N-formylglycineamideoxidized thioredoxinH2OphosphateL-glutamineL-glutamateURA3PRS1ADPATPADPURA4ATPADPL-glutamineADPATPL-glutamateL-glutamateHIS3CDPpyrophosphateL-glutamineHIS4ADE8ADE1GTPADE2phosphateRNR4phosphatePRS5ADPphosphateHIS6dGDPIMD2URA1YNK1ATPATPADE17RNR3NADHHIS4URA10phosphatepyrophosphateURA2ATPL-glutamateAICARHIS5ADPIMD4ADE5,7phosphateRNR1PRPPpyrophosphateATP10-formyl-THFATPL-glycineHIS2ADPURA2phosphateHIS4ATPATPADPHIS1HIS4ATPADE410-formyl-THFL-glutamineL-histidineADE5,7URA7D-ribose-5-phosphateADE16GUK12 ADPYNK1NADHATPGDPpyrophosphatephosphateL-histidinol-phosphateURA6ADE16ADE13phosphateL-glutamateIMD3xanthosine-5-phosphateL-glutamatePRS3L-glutamineADPATPATP2 ATPpyrophosphateRNR2ADE6ATPADE17NADHGMPPRS4ATPADPADPL-glutamineURA8URA5GUA1phosphateADPPRS2L-glutamate


Description

No description

Comments

GenMAPP remarks 
Based on http://pathway.yeastgenome.org/biocyc/

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
107259view14:35, 17 September 2019MaintBotChEBI identifier normalization
94664view13:18, 4 October 2017DeSlChanged ribose-5-P label to D-ribose-5-P
94663view13:17, 4 October 2017DeSlConnected all lines, changed all textlabels to metabolite nodes, connected all genes to the lines.
93079view09:22, 28 July 2017ElisaFixed some of the unconnected interactions (left side of the pathway).
93011view14:46, 24 July 2017DeSlChanged wrong CAS number (salt) for correct ChEBI ID
85638view16:11, 4 June 2016EgonwFixed the CAS number.
71897view10:35, 22 October 2013Mkutmonchanged AICAR from Unknown to Metabolite
70270view21:50, 15 July 2013MaintBotupdated to 2013 schema
69872view18:00, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
67670view11:47, 26 June 2013DdiglesOntology Term : 'nucleotide metabolic pathway' added !
41803view04:48, 2 March 2011MaintBotRemoved redundant pathway information and comments
21558view11:32, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Superpathway of Histidine Purine and Pyrimidine Biosynthesis]] moved to [[Pathway:WP416]]: Moved to stable identifier
12861view08:06, 17 May 2008MaintBotautomated metabolite conversion
8948view14:13, 7 January 2008MaintBotAdded to category $category
8946view14:13, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
10-formyl-THFMetabolite2800-34-2 (CAS)
2 ADPMetabolite58-64-0 (CAS)
2 ATPMetabolite1927-31-7 (CAS)
2-oxoglutarateMetabolite
5-phospho-ribosyl-glycineamideMetabolite
5-phosphoribosyl-n-formylglycineamidineMetabolite
5-phosphoribosylamineMetabolite
5’-phosphoribosyl-4-(N-Metabolite
5’-phosphoribosyl-5-aminoimidazoleMetabolite
5’-phosphoribosyl-N-formylglycineamideMetabolite
ADE13GeneProductS000004351 (SGD)
ADE16GeneProductS000004018 (SGD)
ADE17GeneProductS000004727 (SGD)
ADE1GeneProductS000000070 (SGD)
ADE2GeneProductS000005654 (SGD)
ADE4GeneProductS000004915 (SGD)
ADE5,7GeneProductS000003203 (SGD)
ADE6GeneProductS000003293 (SGD)
ADE8GeneProductS000002816 (SGD)
ADPMetabolite58-64-0 (CAS)
AICARMetabolite3031-94-5 (CAS)
AMPMetabolite
ATPMetabolite1927-31-7 (CAS)
CDPMetabolite63-38-7 (CAS)
CO2Metabolite
CTPMetabolite
D-erythro-imidazole-glycerol-phosphateMetabolite
D-ribose-5-phosphateMetabolite3615-55-2 (CAS)
GDPMetabolite146-91-8 (CAS)
GMPMetabolite85-32-5 (CAS)
GTPMetabolite2564-35-4 (CAS)
GUA1GeneProductS000004830 (SGD)
GUK1GeneProductS000001550 (SGD)
H+Metabolite
H2OMetabolite
HCO3Metabolite
HIS1GeneProductS000000857 (SGD)
HIS2GeneProductS000001921 (SGD)
HIS3GeneProductS000005728 (SGD)
HIS4GeneProductS000000535 (SGD)
HIS5GeneProductS000001378 (SGD)
HIS6GeneProductS000001282 (SGD)
IMD2GeneProductS000001259 (SGD)
IMD3GeneProductS000004424 (SGD)
IMD4GeneProductS000004520 (SGD)
IMPMetabolite
L-aspartateMetabolite
L-glutamateMetabolite56-86-0 (CAS)
L-glutamineMetabolite56-85-9 (CAS)
L-glycineMetabolite56-40-6 (CAS)
L-histidineMetabolite71-00-1 (CAS)
L-histidinol-phosphateMetabolite25679-93-0 (CAS)
NADMetabolite
NADHMetabolite53-84-9 (CAS)
NH3Metabolite
PRPPMetabolite97-55-2 (CAS)
PRS1GeneProductS000001664 (SGD)
PRS2GeneProductS000000901 (SGD)
PRS3GeneProductS000001003 (SGD)
PRS4GeneProductS000000164 (SGD)
PRS5GeneProductS000005422 (SGD)
RNR1GeneProductS000000872 (SGD)
RNR2GeneProductS000003563 (SGD)
RNR3GeneProductS000001328 (SGD)
RNR4GeneProductS000003412 (SGD)
THFMetabolite
UDPMetabolite
UMPMetabolite
URA10GeneProductS000004884 (SGD)
URA1GeneProductS000001699 (SGD)
URA2GeneProductS000003666 (SGD)
URA3GeneProductS000000747 (SGD)
URA4GeneProductS000004412 (SGD)
URA5GeneProductS000004574 (SGD)
URA6GeneProductS000001507 (SGD)
URA7GeneProductS000000135 (SGD)
URA8GeneProductS000003864 (SGD)
UTPMetabolite
YNK1GeneProductS000001550 (SGD)
carbamoyl-L-aspartateMetabolite
carbamoyl-phosphateMetabolite
dGDPMetaboliteCHEBI:28862 (ChEBI)
deoxy-GTPMetabolite
dihydroorotateMetabolite
fumerateMetabolite
histidinalMetabolite
histidinolMetabolite
imidazole acetol-phosphateMetabolite
orotateMetabolite
orotidine-5’-phosphateMetabolite
oxidized flavodoxinMetabolite
oxidized thioredoxinMetabolite
phosphateMetabolite14265-44-2 (CAS)
phosphoribosyl-AMPMetabolite
phosphoribosyl-ATPMetabolite
phosphoribosyl-carboxy-aminoimidazoleMetabolite
phosphoribosyl-formamido-carboxamideMetabolite
phosphoribosylformiminoAICAR-phosphateMetabolite
phosphoribulosylformimino-AICAR-PMetabolite
pyrophosphateMetabolite2466-09-3 (CAS)
reduced flavodoxinMetabolite
reduced thioredoxinMetabolite
sucinocarboxamide)-5-aminoimidazoleMetabolite
xanthosine-5-phosphateMetabolite523-98-8 (CAS)

Annotated Interactions

No annotated interactions
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