Epilepsy adverse outcome pathway (Homo sapiens)
From WikiPathways
Description
Adverse outcome pathway for epilepsy, originating from the AOPXplorer app for Cytoscape (http://apps.cytoscape.org/apps/aopxplorer). The pathway is also under development in the AOPWiki (https://aopwiki.org/aops/215).
Quality Tags
Ontology Terms
Bibliography
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- ''''; https://aopwiki.org/events/1357,
- ''''; https://aopwiki.org/events/1321,
- ''''; https://aopwiki.org/relationships/1452,
- ''''; https://aopwiki.org/events/1354,
- ''''; https://aopwiki.org/relationships/1456,
- ''''; https://aopwiki.org/relationships/1454,
- ''''; https://aopwiki.org/relationships/1460,
- ''''; https://aopwiki.org/events/1359,
- ''''; https://aopwiki.org/relationships/1455,
- ''''; https://aopwiki.org/relationships/1464,
- ''''; https://aopwiki.org/events/1352,
- ''''; https://aopwiki.org/relationships/1457,
- ''''; https://aopwiki.org/events/1362,
- ''''; https://aopwiki.org/relationships/1459,
- ''''; https://aopwiki.org/relationships/1461,
- ''''; https://aopwiki.org/events/1355,
- ''''; https://aopwiki.org/events/1361, PubMed Europe PMC Scholia
- ''''; https://aopwiki.org/relationships/1465,
- ''''; https://aopwiki.org/events/1322,
- ''''; https://aopwiki.org/relationships/1462,
- ''''; https://aopwiki.org/events/1351,
- ''''; https://aopwiki.org/events/1360,
- ''''; https://aopwiki.org/relationships/1463,
- ''''; https://aopwiki.org/events/1349,
- ''''; https://aopwiki.org/events/1350,
- ''''; https://aopwiki.org/events/1363,
- ''''; https://aopwiki.org/relationships/1458,
- ''''; https://aopwiki.org/relationships/1453,
- ''''; https://aopwiki.org/events/1348,
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
GABA-A receptor activation | Protein | Q60147 (Wikidata) ![]() | |
GABA | Metabolite | CHEBI:51374 (ChEBI) ![]() | |
NMDA receptor | Protein | Q414896 (Wikidata) ![]() | |
RDX | Metabolite | CHEBI:24556 (ChEBI) ![]() | |
carbamazepine | Metabolite | CHEBI:3387 (ChEBI) ![]() | |
epilepsy | Q41571 (Wikidata) ![]() | ||
glutamate | Metabolite | CHEBI:18237 (ChEBI) ![]() | https://aopwiki.org/events/1350 |
hippocampal hyperdepolarization | |||
intracellular Cl+ | Metabolite | CHEBI:17996 (ChEBI) ![]() | |
intracellular Na+ | Metabolite | CHEBI:29101 (ChEBI) ![]() | |
membrane depolarization | |||
presynaptic neuron 1 | Q2643251 (Wikidata) ![]() | ||
presynaptic neuron 2 | Q2643251 (Wikidata) ![]() | ||
seizure | Q6279182 (Wikidata) ![]() | ||
voltage gated sodium channel | Protein |
Annotated Interactions
No annotated interactions