Toluene Degradation (Escherichia coli)

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1-8MuconolactoneBenzaldehydeBenzoic acidToluene3-oxoadipatePyrocatecholBenzyl alcohol


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  1. Locher HH, Leisinger T, Cook AM; ''4-Toluene sulfonate methyl-monooxygenase from Comamonas testosteroni T-2: purification and some properties of the oxygenase component.''; J Bacteriol, 1991 PubMed Europe PMC Scholia
  2. Kühner S, Wöhlbrand L, Fritz I, Wruck W, Hultschig C, Hufnagel P, Kube M, Reinhardt R, Rabus R; ''Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1.''; J Bacteriol, 2005 PubMed Europe PMC Scholia
  3. Vardar G, Wood TK; ''Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallol.''; Appl Environ Microbiol, 2004 PubMed Europe PMC Scholia
  4. Leutwein C, Heider J; ''Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria.''; J Bacteriol, 2001 PubMed Europe PMC Scholia
  5. Mampel J, Ruff J, Junker F, Cook AM; ''The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1.''; Microbiology, 1999 PubMed Europe PMC Scholia
  6. Junker F, Saller E, Schläfli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM; ''Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2.''; Microbiology, 1996 PubMed Europe PMC Scholia
  7. Leuthner B, Heider J; ''Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate.''; J Bacteriol, 2000 PubMed Europe PMC Scholia
  8. Junker F, Kiewitz R, Cook AM; ''Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2.''; J Bacteriol, 1997 PubMed Europe PMC Scholia


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106105view12:01, 16 August 2019MaintBotHMDB identifier normalization
85979view14:58, 22 June 2016JacobwindsorModified description
85976view14:28, 22 June 2016JacobwindsorModified description
85975view14:27, 22 June 2016JacobwindsorAdd references
85974view14:16, 22 June 2016JacobwindsorModified description
85970view13:22, 22 June 2016Fehrhartadded MIM interactions
85965view00:23, 22 June 2016KhanspersOntology Term : 'toluene and xylene degradation pathway' added !
85882view21:22, 19 June 2016JacobwindsorFinish Pathway
85881view21:15, 19 June 2016JacobwindsorNew pathway

External references


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NameTypeDatabase referenceComment
3-oxoadipateMetabolite5459800 (PubChem-compound)
BenzaldehydeMetaboliteHMDB0006115 (HMDB)
Benzoic acidMetaboliteHMDB0001870 (HMDB)
Benzyl alcoholMetaboliteHMDB0003119 (HMDB)
MuconolactoneMetabolite542 (PubChem-compound)
PyrocatecholMetaboliteHMDB0000957 (HMDB)
TolueneMetaboliteHMDB0034168 (HMDB)

Annotated Interactions

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