TGF-beta Receptor Signaling Pathway (Rattus norvegicus)

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CytoplasmProteolytic cleavageNUPlasma membraneNUNUCYReaction through unknown mechanisms/moleculesDesumoylationPMCYReceptorRecruitmentSumoylationCYUbiquitinationDeubiquitinationGlycosylationTranslocationNUERNUCY(Protein-protein interaction)DNUMolecule in the pathwayCYGlycosylationNU -> CYCYEnzyme complexExtracellularNUNucleusENGONUCYCYDeacetylationGolgi apparatusMitochondriaCYCYCYNUCYNUNUNUCYDemethylationNU -> CYNUNUMTMethylationProteins in a complex interactionCYEndoplasmic reticulumCYCYControlNUNUCYCYAcetylationCYCYCYNUMolecular associationDephosphorylationPalmitoylationCYNUAutophosphorylationCYECNUNUNUNUNUCYCYEndosomeLigandNUNUNUCYAccession Number: NetPath 7; cellmap:7InhibitionNUActivationCYPhosphorylationKpnb1CDC23PrkcdRbl1Ets1Map3k7Tgfb3Tp53Tgfbr2Smad4FosbPpp2r2aStk11ipTgfbr2Ctnnb1Smad6E2f5Tgfb1PCAFFoxh1Ccnb2Rock1Smad2Axin1Smad3Trap1ENGCited1Snx6Tgfbr3Snip1Rbl2Foxo3Ncoa1STAMBPL1Arrb2Stk11Zfyve9Sp1Anapc4E2F4Snx2Tgfb3SKICrebbpMEF2ATgfbr1Lef1Tgfbr1Eid2JunbSmad7Smad3YAP1RBX1Mapk8Esr1E2F4JundDaxxSmurf2Tgfbr3Smad2Rbl2Tgfbr2Foxg1Map2k3Anapc4Camk2dZeb1Tgfbr3Cdc27Fzr1Hnf4aPrkcbNfybRbl1Snw1Anapc2Esr1Camk2bTgfb1Anapc7SKP1AAnapc1PrkcgTgfbr2E2f5E2F4Smad7Gipc1ArTgfb3StrapHgsTFDP1Ube2d2Acvrl1Tgfbr1FosSmad3Tgfbr2Cd44Smad3FntaXpo1Cdc2Tgfbr1Camk2gFoxo1Rbl1Atf3Hdac1Anapc7Smad3ERBB2IPAp2b1Ep300Rb1Pias2Mapk14Smad3SUMO1Anapc10Smad7VdrJunRunx2Smad3Pard3Anapc5SKP1ARb1Tfdp2Tgif1Mapk14Cav1BtrcPik3r2Ccnd1Cdc27Smurf2Cdkn1aTgfbr2SparcSmad4Tgfbr2Atf2Smad4StrapNup214Cdc27Axin2Cdk6Tgfbr3Pik3r1Kpnb1Snx6Snx4E2F4Dcp1aCamk2aTgfb2Cul1EIF3S2MycE2f5Rbl1Prkar2aSkilGene SymbolTgfbr3Foxo4Rock1Map2k6Cul1Rbl1Sdc2Anapc5Smad4RBX1Smad4Smad3Zeb2Smad2Rb1Pias1E2f5Cul1Tgfbr2Mapk8Snx1Cdc16Tfdp2Tgfb2Anapc1Tgfb3TFDP1Tgfbr3Mef2cCdk2RGD1309707NfycSmad4UBE2D3E2F4Tgfb2Cops5Tp73Smad3E2f5Cdc16Tfdp2Prkar1bMAP3K7IP1Cdk4Hoxa9E2F4Ccne1Dcp1aTFDP1RGD1309707Smad2NfyaDab2Tgfbr2Ube2d1CtcfAnapc2Tgfb1Dvl1RBX1Tgfb1Nup153E2f5Anapc10Hspa8CDC23Fkbp1aCdc25aTgfbr2Btrc


Description

No description

Comments

GenMAPP notes 
NetPath 7; cellmap:7 - TGF-beta Receptor Signaling Pathway

The TGF-beta Receptor Signaling pathway was kindly reviewed by Van Le Hong, Wei He and other members of Joan Massague’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.

GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP366(r21445) with a 88% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
69402view19:00, 8 July 2013MaintBotUpdated to 2013 gpml schema
67696view11:50, 26 June 2013DdiglesOntology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
41723view02:38, 2 March 2011MaintBotRemoved redundant pathway information and comments
34099view19:19, 9 December 2009MaintBotAutomatic update of empty xrefs
31441view21:06, 13 August 2009MaintBotFixed text labels
30987view00:55, 30 July 2009MaintBotConverted from Homo sapiens
21437view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:WP362]]: Moved to stable identifier
8438view13:46, 7 January 2008MaintBot[[Pathway:Rat:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:Rattus norvegicus:TGF-beta-Receptor NetPath 7]]: Renaming species
7835view16:21, 18 December 2007MaintBotfixed category names
7306view12:42, 4 November 2007MaintBotAdded categories to GPML
6601view22:20, 22 May 2007A.Pandeygpml file for [[Rat:TGF-beta-Receptor_NetPath_7]]

External references

DataNodes

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