Selenium Micronutrient Network (Bos taurus)

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81110, 130, 230, 234119, 24322, 70, 72, 86, 90...230703820, 81, 136, 1628148142, 179, 24422, 73124, 2358095194, 20312203137, 138, 162, 166151InhibitionTranscription factorLipid peroxidationReactionCa++ metabolismis composed ofOxidative stressMetabolitesCofactor conversionMetabolic stressBindingInflammation and immune responseLeukotriene metabolismNecessary stimulationProtein tyrosine nitrationFrom intracellular part to the plasmaTryptophan metabolismConversionOverarching processStatusEnzymesNegative EffectCatalysisLipoprotein melabolismBiomarker forCofactorsGlycogenesisCleavageStimulationSelenoproteinsLEGENDProstaglandins metabolismSelenium statusMicronutrientsProcess or metabolism involved in Se PathwayOther proteinsIntracellularGlutathione metabolismNAD+ metabolismER protein foldingFolate metabolismDNA oxidationPlasmaLinoleic acidLinoleic acidPGH2PGE1ALAPGI2DHAPGF2aArachidonic acidPGE2PTGS2a-TocopherolDHAPTGS1ALAPGH3DPALipoxin B4PGG28-Isoprostaglandin F2aPGF2a8-Isoprostaglandin F2aThromboxane B2Lipoxin B4PGE3EPAArachidonic acidF2-IsoprostaneLipoxin A4PGD2Thromboxane B2MDAPGE1NFKB1PGD2Thromboxane A2RELAF2-IsoprostaneDGLAPGE2MDALipoxin A4PGI2DPAa-TocopherolEPANFKB210, 14, 25, 92, 197...1311565, 14518915623614, 35, 49, 60, 70...257, 259156, 200156, 268351896, 5714, 25, 92, 197, 255675, 1455761899167, 156, 178236236236635, 49, 60, 1317315615615624, 1315, 35, 91, 145, 18913173675771, 15649257, 259257, 2596, 57131189Kynurenine194MTR38, 202TXNRD1CBS133, 202IodineIodine5959KMO1945-HETEThyroxine (T4)15-HETETriiodothyronine (T3)Triiodothyronine (T3)5-HETE5,6-EpoxytetraeneR-Triiodothyronine (rT3)Thyroxine (T4)5-HPETER-Triiodothyronine (rT3)15-HETE91, 170, 26791, 170, 2679183, 18491, 23683, 18483, 18423659, 8391, 170, 26759, 8359, 83NADP+CATMPOMPO20, 78, 87, 2582081, 106Uric acid4, 243CysteinePLATF7PLGF2F2GGT1SERPINE1SERPINE1PLGPLATF725425441, 20741, 18325425423841, 18341, 207254254GPX 4TXNRD2XDH4, 15PRDX5H2O2ALOX15BALOX590, 9125, 94, 105, 209, 236CopperUric acid4, 243Vitamin B12116, 2175,10-Methylene-THFSelR75, 136Tryptophan194, 2035-methyl-THFSOD3PRDX1RFK181H2OGPX3NiacinamideCTH202PNPO260Heme81, 95, 106, 133, 178NADPHLipoic acid234ManganeseFAD212Methionine sulfoxide136Dehydroascorbic acid130, 262Leukotriene A456, 102NADPHFAD212THFHydroxykynurenine194Folic acid38NADP+NADPHSeleniumSelenium109109SELENOKSep15138, 162, 251143GPX6GSH147Nicotinamidase203Calcium56Methionine136ManganeseNADPHFolic acid38FMN212SelenideSelenophosphateSelenocysteine83, 11083, 11083, 110CysteineLeukotriene C4Leukotriene C456, 238GPX386Dehydroascorbic acid130GPX2SelP228Trx-S2130, 230, 234Ascorbic acid262Lipoic acid234PRDX4GPX 1NADP+HomocysteineRNSROS2-4, 7, 12...80, 81NADPHVitamin B12116, 217MTHFR38Homocysteine183SELENOSSELENOMDIO1SELENONSELENOOSelPSelHSELENOTSEPHS2DIO2SELENOVSELENOIDIO397, 139, 16659, 8383, 12052, 125, 227, 228263142, 26359, 61, 8359, 83179, 244, 2637, 122, 17, 137263263SOD1Pyridoxal 5'-phosphate194SerineIron56HypoxanthinePRDX3GSR191SCARB1SERPINA3-7ABCA1oxLDLVLDLVLDL/APOBVLDLVLDL-TAGAPOBHDLAPOA1oxLDLHDL/APOA1TAGHDL-CAPOA1LDLVLDL-TAGHDLTAGCholesterolSAA1SERPINA3-7FMNAPOA1APOBHDL/SAASAA2SAA3LDLHDL-CLDLRCholesterolSAA419823522, 87, 124, 19282, 10823510, 22, 87, 124, 1922358223510, 22, 87, 124, 19223522, 87, 124, 192140, 235140, 2358282235220140, 235235140, 23536235212828236, 140, 23553, 164, 1988253, 164, 19823536, 2358282, 108O273Pyridoxal 5'-phosphate1948-OHdGFAD8-OHdG151151212PRDX2ADPLeukotriene D4Leukotriene D4238ChlorineCopperChlorineCystathionineFAD212SOD2Dihydrolipoate13, 234SerineNADP+ATPZincNADP+GSSGNADPHZincNiacinLeukotriene B4Leukotriene B456, 102102Quinolinic Acid194, 203PMPHNO2NOO3HOClNONO278, 25878, 258NADP+GSH12, 102, 147D-dimerCCL2IL1BCRPFibrinogenTNFIFNGHbA1cIL6HbA1cICAM1IL1BINSRCCL2INSTNFINSHBAIFNGIFNGIFNGFibrinogenALBD-dimerFibrinHBGICAM1FibrinALBALOX5APIL628, 2544661, 226, 2331393, 523, 5228, 254123, 176, 1873, 139, 176, 261666666125, 139, 26148, 76, 88, 108, 225612262096148, 76, 88, 22588, 22513961, 125, 17610, 22, 123, 233207, 2544622652207, 25466123, 176, 18752SELENOW55, 147, 172Riboflavin62SOD3119TXNRD1230Ascorbate130, 262O2-“XanthineCalcium56KYNU194Methionine136ADPTrx-(SH)2230, 234NitrotyrosineONOO-/ONOOHNitrotyrosine8080ATPLeukotriene E4Leukotriene E4238FructosamineLeukotriene F4FructosamineGlucose464634, 23848, 66Iron56HypoxanthineTXNRD3FLAD163, 181Ascorbic acid92, 255, 262