Sulindac Metabolic Pathway (Bos taurus)

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1CYP1B1MSRB2MSRASulfindac sulfideSulindac-SFMOSulindac-RSulindac sulfoneMSRB3CYP1A2CYP1A2


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2542(70621) with a 85.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Brunell D, Sagher D, Kesaraju S, Brot N, Weissbach H; ''Studies on the metabolism and biological activity of the epimers of sulindac.''; Drug Metab Dispos, 2011 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
97757view13:18, 7 June 2018Mick EikelhofModified description
87598view08:13, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
80713view15:23, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CYP1A2GeneProductENSBTAG00000000085 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1GeneProductENSBTAG00000010531 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
FMOGeneProduct
MSRAGeneProductENSBTAG00000021632 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000175806
MSRB2GeneProductENSBTAG00000044112 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148450
MSRB3GeneProductENSBTAG00000044017 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174099
Sulfindac sulfideMetabolite4509492 (Chemspider)
Sulindac sulfoneMetabolite4582441 (Chemspider) The structure for the sulfone in the paper is inconsistent with the entries in ChemSpider and PubChem; I assume the paper made typographic errors.
Sulindac-RMetabolite16046677 (PubChem-compound)
Sulindac-SMetabolite11245227 (PubChem-compound)

Annotated Interactions

No annotated interactions
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