TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) (Bos taurus)

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Pyruvate Dehydrogenase ComplexSDHAACLYIDH3APDHA1SUCLG2SuccinateOGDHOxaloacetateDLST2-Oxo-glutarateOGDH3-carboxy-1-hydroxypropyl-ThPPFumaratePhosphoenol-pyruvateMDH1S-Succinyl-dihydrolipoamide-E(S)-MalateGlycolysisCitrateCSDLATPCK1ACO1IDH1DLDLipoamide-EOxalosuccinate2-Hydroxy-ethyl-ThPPThPPDihydro-lipoamide-EIDH1IsocitrateFHAcetyl-CoASuccinoyl-CoAPCPyruvateS-Acetyldihydro-lipoamide-EPDHA1ThPPDihydro-lipoamide-ELipoamide-EDLD


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2453(80143) with a 100.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
107061view14:14, 17 September 2019MaintBotChEBI identifier normalization
87730view09:24, 25 July 2016MirellaKalafatiOntology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87729view09:23, 25 July 2016MirellaKalafatiOntology Term : 'PW:0001752' removed !
87728view09:23, 25 July 2016MirellaKalafatiOntology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87727view09:22, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87726view09:21, 25 July 2016MirellaKalafatiOntology Term : 'disease pathway' added !
87725view09:21, 25 July 2016MirellaKalafatiModified title
87364view09:50, 22 July 2016MaintBotadded missing graphids
80712view15:23, 30 June 2015MkutmonNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
(S)-MalateMetaboliteC00149 (KEGG Compound)
2-Hydroxy-ethyl- ThPPMetaboliteC05125 (KEGG Compound)
2-Oxo-glutarateMetaboliteC00026 (KEGG Compound)
3-carboxy-1- hydroxypropyl-ThPPMetabolite
ACLYGeneProductENSBTAG00000016740 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000131473
ACO1GeneProductENSBTAG00000000555 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122729
Acetyl-CoAMetaboliteC00024 (KEGG Compound)
CSGeneProductENSBTAG00000004371 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000062485
CitrateMetaboliteC00158 (KEGG Compound)
DLATGeneProductENSBTAG00000038327 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000150768
DLDGeneProductENSBTAG00000001908 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091140
DLSTGeneProductENSBTAG00000006463 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000119689
Dihydro- lipoamide-EMetabolite
Dihydro- lipoamide-EMetaboliteCHEBI:80219 (ChEBI)
FHGeneProductENSBTAG00000021688 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000091483
FumarateMetaboliteC00122 (KEGG Compound)
GlycolysisPathwayWP534 (WikiPathways)
IDH1GeneProductENSBTAG00000020527 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138413
IDH3AGeneProductENSBTAG00000006227 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000166411
IsocitrateMetaboliteC00311 (KEGG Compound)
Lipoamide-EMetaboliteC15972 (KEGG Compound)
MDH1GeneProductENSBTAG00000019295 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000014641
OGDHGeneProductENSBTAG00000006029 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105953
OxaloacetateMetaboliteC00036 (KEGG Compound)
OxalosuccinateMetaboliteC05379 (KEGG Compound)
PCGeneProductENSBTAG00000019700 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5091
PCK1GeneProductENSBTAG00000001936 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000124253
PDHA1GeneProductENSBTAG00000019852 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000131828
Phosphoenol- pyruvateMetaboliteC00074 (KEGG Compound)
PyruvateMetaboliteC00022 (KEGG Compound)
S-Acetyldihydro- lipoamide-EMetaboliteC16255 (KEGG Compound)
S-Succinyl- dihydrolipoamide-EMetabolite
SDHAGeneProductENSBTAG00000046019 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000073578
SUCLG2GeneProductENSBTAG00000009541 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000172340
SuccinateMetaboliteC00042 (KEGG Compound)
Succinoyl-CoAMetaboliteC00091 (KEGG Compound)
ThPPMetaboliteC00068 (KEGG Compound)

Annotated Interactions

No annotated interactions
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