SIDS Susceptibility Pathways (Bos taurus)

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10576971724312511088036, 94, 10411499106322652, 8447, 79441007711271046578109477311512511523323, 88, 12323716911537373939463723379112569101231221179512212255, 8212221222, 6821227012235106352, 6895583535122235122122Nerve TerminalSPhCardiac myocyteOther4R/4RDecreased relative SIDS expressionMiscelaneous SIDS AssociatedGs signalingTRrAssociated with Infection and SIDSPutative TRSerotonin Signaling2+Putative TRSoma MembraneSerotoninTransporterNH2Putative TRSIDS Susceptibility Pathwaysp+HOSarcoplasmic ReticulumPutative TRsGq signalingcircadianHeartPutative TRsRapidly-activating K+ CurrentG-protein BrownAdiposePutative TRSPhdepressionInfant (<1 year in age)Putative TR Slowly-Activating K+ CurrentVagal ToneBradycardiaPutative TRsIVS-191_190insAStabilizationNucleusTRrCaG5477AHNSleepNucleusTR: Transcriptional RegulationPutative TRPutative TRsPutative TRG2989TSIDS associated polymorphismsPutative TRsNa+BrainPutative TRsSph: SIDS Phenotype Animal ModelSerotonin Synthesis and MetabolismC825TIncreased brainstem hypoplasia with SIDSCell MembraneBrainstem neuronSPhIncreased relative SIDS expressionK+Putative TRsrs2856966SPhK+Increased long-QT with SIDSGi signalingFocal AdhesionsAssociated with Energy Metabolism and SIDSThermoregulation828604910216186012317123SP3RUNX3CREBBPKCNQ1ALDOAIL10IL6MAZ5HTR1ACHRNB4SP1NKX2-2CC2D1A5-HIAAPOU3F2HADHAC4BHIF1AADCYAP1NEUROD15-HTRORACXCL8SSTR2MAOAHIF1AAREP300L-TryptophanDLX2EGR1TCF3MEF2CNicotineSSTR1NKX3-1IL6RRYR2PHOX2BDEAF1THRBCREB1GATA2bta-mir-130aVIPR1CAV3KCNH2MGC157163TLX35-HTPVIPR2AVPESR2GATA3EN1CHRNA4SP1RYR2PLP1LMX1BRETMGC157163PPARGC1ANK1RTPH2PKNOX1PPARGC1BYBX1POU3F2ADCYAP1R1GR-ACREB15-HTTNFHSPD1CDCA7LNGFPBX1GR-ATPH1GNB3HTR2AMAOAACADMSLC6A4SP1KCNQ1TP73bta-mir-210CTCFSP1TPH15-HTTPH25HTR1AFEVCAV3ADCYAP1NFKB1KCNH2DDCJUNGlial Cell DifferentiationNFYAPHOX2AASCL1CREB1C4AMGC157163SCN5AHES1HES1DDCHES5FEVNFKB1MGC157163bta-mir-16aSP1ECE1FOXM1FluoxetineBHLHE40MGC15716311147931122029343755665745119103928348791415461251105471, 745923561043411812424Putative TRsCTNNB1SOX2NANOGPOU5F124MAPK pathway2BDNFNTRK2Gi signalingGABA21GABRA1CHRM285GJA1113SNTA1Na+H+40K+KCNJ8GJA1PKC inhibitor 14-3-3Protein Kinase APRKAR2BYWHAEYWHAZPRKAR1BPRKAR2AYWHAQYWHAGPRKAR1AYWHAHYWHABPRKACBPRKACAActivation121GAP JunctionSLC9A3CASP3FMO333G6PC50GCKGPD1L120GRIN1HADHBHTR3A9SCN3BSCN4BSSTNa+Cardiac VagalExcitationChronicHypoxia75-HTGlutamateCa2+75H2OH2OAQP4ApoptosisCPT1AIL1A64IL1B42IL1RN42107IL1353TSPYL1VEGFA6719SCN5A26DopaminePhenylalanineCHATL-DOPAPAHAcetylcholineCholineTHTyrosineDDCNOS1AP30Gq signalingMAP-251TAC1MicrotubleStabilizationSLC1A3SLC25A4GlutamateSNAP25Synaptic Vesicle ReleaseGlutamate51SST51TAC1HTR3A97TH76CHAT11758SLC9A3BDNFNTRK22AQP475GRIN143SP1NFKB290JUN41HDAC9MYB96CEBPB72SNTA1113GPD1LSP1JUNGR-A44MGC15716381JUNCREB1POU2F2CREM62MGC157163NFKB1CHRNB2CHRNA7Serotonergic NeuronsHDAC1MBD1MECP2NFKB1CREBBPTRrTRrGABRA121CREB198VAMP2Extracellular SpacePutative TRsPutative TRsPutative TRsPutative TRsPutative TRsPutative TRsPutative TRsPutative TRsPutative TRsTPPPATP1A3GAPDHHSP90B1TFSPTBN1YWHAGHIF1APutative TRs10923