Serotonin Receptor 2 and STAT3 Signaling (Bos taurus)

From WikiPathways

Jump to: navigation, search
1, 7, 9, 11, 13...122-6, 17, 1810, 168serotoninHTR2ASTAT3JAK2GNAQ


Description

Source: Ariadne Genomics Pathway Studio.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP733(74441) with a 100.0% conversion rate.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Flowers LO, Subramaniam PS, Johnson HM; ''A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells.''; Oncogene, 2005 PubMed Europe PMC
  2. Butts DA, Rokhsar DS; ''The information content of spontaneous retinal waves.''; J Neurosci, 2001 PubMed Europe PMC
  3. Goppelt-Struebe M, Stroebel M; ''Mechanisms of serotonin-induced Ca2+ responses in mesangial cells.''; Naunyn Schmiedebergs Arch Pharmacol, 1997 PubMed Europe PMC
  4. Imada-Shirakata Y, Kotera T, Ueda S, Okuma M; ''Serotonin activates electrolyte transport via 5-HT2A receptor in rat colonic crypt cells.''; Biochem Biophys Res Commun, 1997 PubMed Europe PMC
  5. Cox DA, Watts SW, Cohen ML; ''Neomycin selectively inhibits 5-hydroxytryptamine-induced contraction in the guinea pig trachea.''; J Pharmacol Exp Ther, 1996 PubMed Europe PMC
  6. Dougalis A, Lees G, Ganellin CR; ''The sleep inducing brain lipid cis-oleamide (cOA) does not modulate serotonergic transmission in the CA1 pyramidal neurons of the hippocampus in vitro.''; Neuropharmacology, 2004 PubMed Europe PMC
  7. Hattori R, Maulik N, Otani H, Zhu L, Cordis G, Engelman RM, Siddiqui MA, Das DK; ''Role of STAT3 in ischemic preconditioning.''; J Mol Cell Cardiol, 2001 PubMed Europe PMC
  8. Guillet-Deniau I, Burnol AF, Girard J; ''Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway.''; J Biol Chem, 1997 PubMed Europe PMC
  9. Waris G, Turkson J, Hassanein T, Siddiqui A; ''Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication.''; J Virol, 2005 PubMed Europe PMC
  10. Damjanoska KJ, Van de Kar LD, Kindel GH, Zhang Y, D'Souza DN, Garcia F, Battaglia G, Muma NA; ''Chronic fluoxetine differentially affects 5-hydroxytryptamine (2A) receptor signaling in frontal cortex, oxytocin- and corticotropin-releasing factor-containing neurons in rat paraventricular nucleus.''; J Pharmacol Exp Ther, 2003 PubMed Europe PMC
  11. Murata S, Usuda N, Okano A, Kobayashi S, Suzuki T; ''Occurrence of a transcription factor, signal transducer and activators of transcription 3 (Stat3), in the postsynaptic density of the rat brain.''; Brain Res Mol Brain Res, 2000 PubMed Europe PMC
  12. Ferrand A, Kowalski-Chauvel A, Bertrand C, Escrieut C, Mathieu A, Portolan G, Pradayrol L, Fourmy D, Dufresne M, Seva C; ''A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models.''; J Biol Chem, 2005 PubMed Europe PMC
  13. Lo RK, Wong YH; ''Signal transducer and activator of transcription 3 activation by the delta-opioid receptor via Galpha14 involves multiple intermediates.''; Mol Pharmacol, 2004 PubMed Europe PMC
  14. Ni CW, Hsieh HJ, Chao YJ, Wang DL; ''Interleukin-6-induced JAK2/STAT3 signaling pathway in endothelial cells is suppressed by hemodynamic flow.''; Am J Physiol Cell Physiol, 2004 PubMed Europe PMC
  15. Kamakura S, Oishi K, Yoshimatsu T, Nakafuku M, Masuyama N, Gotoh Y; ''Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling.''; Nat Cell Biol, 2004 PubMed Europe PMC
  16. Li Q, Muma NA, Battaglia G, Van de Kar LD; ''Fluoxetine gradually increases [125I]DOI-labelled 5-HT2A/2C receptors in the hypothalamus without changing the levels of Gq- and G11-proteins.''; Brain Res, 1997 PubMed Europe PMC
  17. Boyarsky BK, Haque W, Rouleau MR, Hirschfeld RM; ''Sexual functioning in depressed outpatients taking mirtazapine.''; Depress Anxiety, 1999 PubMed Europe PMC
  18. Piera MJ, Beaughard M, Michelin MT, Winslow E, Massingham R; ''Lack of efficacy of 5-HT2A receptor antagonists to reduce brain damage after 3 minutes of transient global cerebral ischaemia in gerbils.''; Fundam Clin Pharmacol, 1995 PubMed Europe PMC

History

CompareRevisionActionTimeUserComment
101985view21:15, 21 November 2018EgonwRemoved whitespace in PubMed identifiers.
80659view15:21, 30 June 2015MkutmonNew pathway

External references

DataNodes

NameTypeDatabase referenceComment
GNAQGeneProductENSBTAG00000009789 (Ensembl)
  • guanine nucleotide binding protein, alpha q polypeptide
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2776
HTR2AGeneProductENSBTAG00000013498 (Ensembl)
  • 5-hydroxytryptamine (serotonin) receptor 2A
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3356
JAK2GeneProductENSBTAG00000012047 (Ensembl)
  • Janus kinase 2
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3717
STAT3GeneProductENSBTAG00000021523 (Ensembl)
  • signal transducer and activator of transcription
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774
serotoninMetabolite50-67-9 (CAS)

Annotated Interactions

No annotated interactions
Personal tools