mir34a and TGIF2 in osteoclastogenesis (Homo sapiens)

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1Osteoclast progenitorTumor cellOsteoporosisBone metastasisBone resorptionOsteoblastTGIF2MIR34AOsteoclast


A model for how miR-34a suppresses osteoclastogenesis.

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Ontology Terms



  1. Krzeszinski JY, Wei W, Huynh H, Jin Z, Wang X, Chang TC, Xie XJ, He L, Mangala LS, Lopez-Berestein G, Sood AK, Mendell JT, Wan Y; ''miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.''; Nature, 2014 PubMed


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87842view11:48, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
78507view10:29, 7 January 2015MaintBotadded missing graphIds
77995view18:48, 4 November 2014KhanspersOntology Term : 'cancer' added !
77994view18:47, 4 November 2014KhanspersOntology Term : 'skeletogenic cell' added !
77993view18:39, 4 November 2014KhanspersOntology Term : 'bone disease' added !
77992view18:38, 4 November 2014KhanspersModified description
77991view18:34, 4 November 2014KhanspersAdded pathway data nodes
77781view18:38, 17 October 2014KhanspersModified title
77780view18:33, 17 October 2014KhanspersNew pathway

External references


NameTypeDatabase referenceComment
MIR34ARna407040 (Entrez Gene)
OsteoblastPathwayWP322 (WikiPathways)
OsteoclastPathwayWP12 (WikiPathways)
TGIF2GeneProduct60436 (Entrez Gene)

Annotated Interactions

No annotated interactions

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