Apoptosis-related network due to altered Notch3 in ovarian cancer (Homo sapiens)

From WikiPathways

Jump to: navigation, search


Results of pathway analysis of apoptosis-related genes in OVCAR3 cells treated with Notch3 siRNA or control siRNA. Proteins on this pathway have targeted assays available via the CPTAC Assay Portal

Quality Tags

Ontology Terms



  1. Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK; ''Notch3 pathway alterations in ovarian cancer.''; Cancer Res, 2014 PubMed Europe PMC Scholia


View all...
108133view10:30, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
106299view17:42, 20 August 2019KhanspersModified description
105531view06:02, 9 August 2019KhanspersModified description
79278view22:22, 19 March 2015ZariAdded Identifier for BCL3
77986view18:12, 4 November 2014KhanspersOntology Term : 'apoptotic cell death pathway' added !
77869view19:11, 23 October 2014KhanspersModified title
77856view21:04, 22 October 2014KhanspersOntology Term : 'reproductive organ cancer' added !
77776view18:21, 17 October 2014Khanspersadded lit ref
77775view18:16, 17 October 2014KhanspersModified description
77774view18:12, 17 October 2014KhanspersNew pathway

External references


View all...
NameTypeDatabase referenceComment
ABL1GeneProduct25 (Entrez Gene)
AKT1GeneProduct207 (Entrez Gene)
ANXA5GeneProduct308 (Entrez Gene)
APOEGeneProduct348 (Entrez Gene)
APPGeneProduct351 (Entrez Gene)
AXIN1GeneProduct8312 (Entrez Gene)
BCL3Protein602 (Entrez Gene)
BIRC5GeneProduct332 (Entrez Gene)
CARD14GeneProduct79092 (Entrez Gene)
CASP7GeneProduct840 (Entrez Gene)
CDKN1AGeneProduct1026 (Entrez Gene)
CDKN1BGeneProduct1027 (Entrez Gene)
CSDAGeneProduct8531 (Entrez Gene)
CTNNA1GeneProduct1495 (Entrez Gene)
CUL1GeneProduct8454 (Entrez Gene)
CUL5GeneProduct8065 (Entrez Gene)
ERBB3GeneProduct2065 (Entrez Gene)
ERN1GeneProduct2081 (Entrez Gene)
ETS1GeneProduct2113 (Entrez Gene)
F2RGeneProduct2149 (Entrez Gene)
GCLCGeneProduct2729 (Entrez Gene)
HDAC1GeneProduct3065 (Entrez Gene)
HELLSGeneProduct3070 (Entrez Gene)
HSPA5GeneProduct3309 (Entrez Gene)
HSPB1GeneProduct3315 (Entrez Gene)
HSPD1GeneProduct3329 (Entrez Gene)
IER3GeneProduct8870 (Entrez Gene)
IL7RGeneProduct3575 (Entrez Gene)
JUNDGeneProduct3727 (Entrez Gene)
MAPK1GeneProduct5594 (Entrez Gene)
NET1GeneProduct10276 (Entrez Gene)
NFKB1GeneProduct4790 (Entrez Gene)
NGFRAP1GeneProduct27018 (Entrez Gene)
NQO1GeneProduct1728 (Entrez Gene)
NRG1GeneProduct3084 (Entrez Gene)
PAK2GeneProduct5062 (Entrez Gene)
PKN1GeneProduct5585 (Entrez Gene)
PTK2GeneProduct5747 (Entrez Gene)
PTK2BGeneProduct2185 (Entrez Gene)
RIPK2GeneProduct8767 (Entrez Gene)
RNF7GeneProduct9616 (Entrez Gene)
RPS6KB1GeneProduct6198 (Entrez Gene)
SERBP1GeneProduct26135 (Entrez Gene)
SMAD7GeneProduct4092 (Entrez Gene)
SOCS3GeneProduct9021 (Entrez Gene)
SQSTM1GeneProduct8878 (Entrez Gene)
THBS1GeneProduct7057 (Entrez Gene)
TNFGeneProduct7124 (Entrez Gene)
TNFRSF10BGeneProduct8795 (Entrez Gene)
TNFRSF21GeneProduct27242 (Entrez Gene)
TRAF1GeneProduct7185 (Entrez Gene)
VAV3GeneProduct10451 (Entrez Gene)
VIMGeneProduct7431 (Entrez Gene)

Annotated Interactions

No annotated interactions

Personal tools