Glucose Repression (Saccharomyces cerevisiae)

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1ADPVacuoleSNF1Glucose 6-phosphateGTPSAC1GDPGLC7REG1SNF4GlycolysisHXT7D-GlucoseSIP1D-GlucoseSNF1PSNF4SNF1PSNF4SNF1PSNF4PSNF1GAL83SIP2TOS1ELM1GTPGDPADPADPADPSNF4SNF1GAL83P


Description

Glucose repression is a widespread phenomenon in microorganisms, whereby cells grown on glucose repress the expression of a large number of genes that are required for the metabolism of alternate carbon sources.

In the yeast Saccharomyces cerevisiae, glucose repression affects the enyzmes required for metabolism of the sugars sucrose, maltose, and galactose, and non-fermentable carbon sources such as glycerol, ethanol, and acetate, as well as gluconeogenic and respiratory enzymes and mitochondrial development. With very few exceptions, glucose control Is exercised at the level of transcription.

Source: Glucose repression in the yeast Saccharomyces cerevisiae. Trumbly RJ, Mol Microbiol. 1992 Jan;6(1):15-21. http://www.ncbi.nlm.nih.gov/pubmed/1310793

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Ontology Terms

 

Bibliography

  1. Trumbly RJ; ''Glucose repression in the yeast Saccharomyces cerevisiae.''; Mol Microbiol, 1992 PubMed Europe PMC

History

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CompareRevisionActionTimeUserComment
107016view13:47, 17 September 2019MaintBotHMDB identifier normalization
87549view02:11, 25 July 2016AlexanderPicoOntology Term : 'classic metabolic pathway' added !
87548view02:11, 25 July 2016AlexanderPicoOntology Term : 'glucose reduction pathway' added !
79835view09:48, 17 April 2015EgonwReplaced the Ensembl Yeast datasources with SGD (manually confirmed the identifier-label match).
78395view10:25, 7 January 2015MaintBotadded missing graphIds
78127view18:49, 4 December 2014KhanspersAdded states, fixed layout, added xrefs, connected interactions
78126view18:36, 4 December 2014KhanspersModified description
77646view14:14, 1 October 2014EgonwFixed the database attribute of two identifiers.
77554view23:41, 23 September 2014SelinadSpecify description
77553view23:39, 23 September 2014Selinadadd nucleus
77549view23:29, 23 September 2014SelinadSpecify description
77546view23:21, 23 September 2014SelinadPeriodical save, work in progress
77544view23:07, 23 September 2014Selinadadp
77542view22:35, 23 September 2014SelinadPeriodical save, work in progress
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77127view22:32, 21 July 2014SelinadNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
D-GlucoseMetaboliteHMDB0000122 (HMDB)
ELM1GeneProductS000001531 (SGD)
GAL83GeneProductS000000829 (SGD)
GDPMetaboliteHMDB0001201 (HMDB)
GLC7GeneProductS000000935 (SGD)
GTPMetaboliteHMDB0001273 (HMDB)
Glucose 6-phosphateMetaboliteHMDB0001401 (HMDB)
GlycolysisPathwayWP253 (WikiPathways)
HXT7GeneProductS000002750 (SGD)
REG1GeneProductS000002435 (SGD)
SAC1GeneProductS000001695 (SGD)
SIP1GeneProductS000002830 (SGD)
SIP2GeneProductS000003176 (SGD)
SNF1GeneProductS000002885 (SGD)
SNF4GeneProductS000003083 (SGD)
TOS1GeneProductS000000366 (SGD)

Annotated Interactions

No annotated interactions

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