Fc epsilon receptor (FCERI) signaling (Homo sapiens)

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21, 1458055, 74, 7649, 79, 104, 11741, 48, 1003, 8, 31, 1157838, 94, 106, 11926, 1418, 4657, 12528, 86, 98, 107, 124...5, 6, 9, 3239, 50, 111, 13139, 11137, 11849, 62, 14725, 1233, 12, 11458, 81, 85121, 14882, 132, 14977, 133, 1394018, 38, 687, 45, 88, 904, 209991, 128, 13773107109108, 14459, 71, 136, 14234, 93, 14015, 97, 120, 122, 12759, 71, 136, 14211646, 52, 1004714, 5451, 10135, 4442, 1036025, 67, 75, 90, 1386517, 4710, 29, 56, 102, 146112, 130, 1436119, 8453, 72, 8322, 64, 92, 110nucleoplasmendoplasmic reticulum lumencytosolIGKV2-28 DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6 oligomerIg kappa chain V-I region AU ATPPI(3,4)P2 Ig lambda chain V-I region HA H2Op-5Y-LAT-2 GRB2-1 Ig lambda chain V-II region BOH TEC,BTK,ITK,(TXK)p-Y172-VAV2 PSMC4 IGLV5-37(1-?) p-S177,S181-IKKB:IKKA:NEMOp-Y239,Y240,Y317-SHC1-2 PI(3,4,5)P3 Zn2+ IGKV2-28 IGHV(1-?) p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAVK48PolyUb-K21,22-p-S32,S36-IkBA RasGRPsIg lambda chain V region 4A Ub-276-UBC(229-304) IGLV2-33(1-?) IGKV4-1(21-?) p-Y239,Y240,Y317-SHC1-2 Ig lambda chain V-I region NEWM IGLV7-46(1-?) IGLV2-23(1-?) IGLV11-55(1-?) IGLV5-37(1-?) ADPIg heavy chain V-II region OU Ig lambda chain V-II region TOG IGLV1-44(1-?) IGLV5-45(1-?) IGLV3-16(1-?) GTPVAV2 Ig kappa chain V-I region HK101 NFKBIA IGHV(1-?) GRAP2 RASGRP4 FCERI:IgEIg kappa chain V-II region FR p-S32,36-IkB-alpha:NF-kB complexPSMB2 Ig heavy chain V-III region TRO Ig heavy chain V-I region EU ADPIg heavy chain V-II region WAH IGLV1-44(1-?) p-CARMA1 oligomer Ig kappa chain V-I region Wes p-Y91,Y420-TXK MALT1 oligomer Ig heavy chain V-II region ARH-77 IgH heavy chain V-III region VH26 precursor Clusteredp:LYN:p-FCERI:IgE:allergin:p-6Y-SYKFOSK48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complexPI(3,4,5)P3 Ig kappa chain V-III region B6 IGLV3-12(1-?) Ig kappa chain V-I region HK101 Ig kappa chain V-III region B6 Ig heavy chain V-II region ARH-77 IGLV1-44(1-?) Ig lambda chain V-II region BOH p-T221,Y223-MAPK10 Ig heavy chain V-III region WEA p-Y512-ITK PSMA4 p-T1400,T1412-MAP3K1SOS1 Ub-48-UBC(1-76) Ig kappa chain V-II region Cum Ig heavy chain V-III region BRO NFKB1(1-433):RELAIGLV2-18(1-?) FCER1G IGLV8-61(1-?) FBXW11 NFAT:CaN:CaMp-S257-NFATC1 Ig heavy chain V-I region HG3 Ig lambda chain V-III region LOI NFKB1(1-433) Ig heavy chain V-II region OU IGLV4-60(1-?) PLCG1 ITPR1 Ig kappa chain V region EV15 p-Y223,Y551-BTK S-Farn-Me KRAS4B Ig lambda chain V-I region VOR IGLV10-54(1-?) IGKV1-12 IGHE PI(4,5)P2Ig kappa chain V-II region RPMI 6410 Ca2+TRAF6ITK IGHV7-81(1-?) SCF-beta-TRCPCa2+ PPP3CB IGLV3-27(1-?) Ig kappa chain V region EV15 CHUK PI(3,4,5)P3 CALM1 Ig lambda chain V-I region NEW ATPK48-UbMALT1 oligomer IGKV1-12 p-Y239,Y240,Y317-SHC1-2 Ub-48-RPS27A(1-76) GRAP2 ATPSOS1 PIK3R1 p-Y239,Y240,Y317-SHC1-2 IGHE MAPK9 Ig kappa chain V-I region BAN p-T185,Y187-MAPK1 GRB2-1 Ig heavy chain V-III region BUT IGKVA18(21-?) Ig kappa chain V-I region AG MAPK10 IGLV4-69(1-?) CALM1 GTP VAV3 GRB2-1 IGKVA18(21-?) IGLC7 Ub-428-UBC(381-456) Ig lambda chain V-I region HA VAV1 ATPIg heavy chain V-II region MCE PLCG1 Ig lambda chain V-II region BOH IGHE IGKV3D-20 IGLV1-36(1-?) Ig heavy chain V-II region NEWM IGLV3-22(1-?) Ig kappa chain V-I region Daudi ITPR2 Ig kappa chain V-I region Daudi PAK1 Ig lambda chain V-II region TOG TEC p-Y90-PKC-theta:DAGIGLV3-16(1-?) IKBKG Ig lambda chain V-IV region Hil p-T221,Y223-MAPK10 DAGsIg kappa chain V-II region FR p-NFATC1,2,3DAGs LYNTEC ADPSOS1 p-Y239,Y240,Y317-SHC1-2GRB2-1 p-Y206,Y519-TEC S-Farn-Me-PalmS KRAS4A SOS1 PI(3,4)P2 Ig heavy chain V-II region OU IGLV5-45(1-?) IGLV2-23(1-?) IGLC1 TRAF6 IGLV2-23(1-?) Ig heavy chain V-III region BRO IGLC6 IGLC2 ADPPSMB1 IGLV4-3(1-?) ATPIg heavy chain V-I region EU I(1,4,5)P3 PLCG2 p-5Y-PKC-theta:DAGIg kappa chain V-I region AU IGKV3D-20 Allergin Ig heavy chain V-III region TRO IgH heavy chain V-III region VH26 precursor Ub-200-UBB(153-228) PI(3,4,5)P3 p-T,Y-MAPK8 GRB2-1 GRAP2 PSMC2 SYK Ig lambda chain V-IV region Hil Ig lambda chain V-I region VOR p-Y239,Y240,Y317-SHC1-2 Ig lambda chain V-II region TOG IGKC Ig lambda chain V-IV region Bau Ig heavy chain V-II region WAH IkB(alpha):NF-kBcomplexTAB2 ATPPSMD2 DAGs IGKC PI(3,4,5)P3 IGLC7 Ca2+ Ig heavy chain V-III region JON Ig heavy chain V-III region BRO BCL10 oligomer RASGRP1 PSMD5 RASGRP2 Ig kappa chain V-III region VG p21 RAS:GDPIg lambda chain V-IV region Kern p-S552-CARD11 Ig lambda chain V-II region MGC p-MAPK8,9,10Ig heavy chain V-II region WAH p-Y206,Y519-TEC IGLV11-55(1-?) LCP2 DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6Ig heavy chain V-III region KOL IGLC2 IGKV1-12 Ig heavy chain V-II region MCE p-Y113,128,145-LCP2 PSMA5 Ig lambda chain V region 4A GRB2-1 Ig heavy chain V-II region NEWM IGLV8-61(1-?) IgH heavy chain V-III region VH26 precursor PI(3,4,5)P3IGLC1 Ub-TRAF6 trimerbound to CBMcomplexTAB3 Ig heavy chain V-III region BUT p-5Y-LAT-2 Ig kappa chain V-III region POM SOS1 p-CARMA1 oligomer IGLV1-36(1-?) p-Y452,Y476,Y584-GAB2 PSME1 Ig heavy chain V-III region DOB Ig heavy chain V-I region EU Ig lambda chain V-IV region Bau UBE2D1 IGLC1 VAV1 IGLC3 IGLV2-11(1-?) GRB2-1 PIK3R2 Ig lambda chain V-I region VOR p-12S-NFATC1 Ig lambda chain V-II region BOH VAV3 Ig kappa chain V-III region POM PLCG1 ITPR3 Ig heavy chain V-II region ARH-77 p-S144,T423-PAK1 PPP3CB Ig lambda chain V-I region NEW NFKB1(1-433) p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3PSMD4 DAG:p-5Y-PKC-theta:CBM oligomer:TRAF6Ig lambda chain V-IV region Bau IGKV4-1(21-?) Ig heavy chain V-II region WAH BCL10 PIK3CA MALT1p-Y396-LYN GADS:SLP76Ig lambda chain V-I region NEWM p-Y91,Y420-TXK Ig kappa chain V-I region DEE VAV3 PSMC5 MAP3K7 IGHV(1-?) Ig kappa chain V-III region POM Ig lambda chain V-IV region Bau p-Y551-BTK Ig heavy chain V-II region ARH-77 PLCG2 S-Farn-Me KRAS4B Ig lambda chain V-IV region Kern IGLV1-40(1-?) IGLV2-33(1-?) p-Y90,T219,T538,S676,S695-PRKCQ Ig heavy chain V-III region CAM ADPp-Y512-ITK Ig heavy chain V-III region KOL Ig lambda chain V-III region LOI Ub-580-UBC(533-608) PLCG2 PIK3CB Ig heavy chain V-II region WAH IGLV5-45(1-?) IGLV4-60(1-?) p-Y396-LYN GRB2-1 BCL10 oligomer SOS1 p-Y173-VAV3 p-Y239,Y240,Y317-SHC1-2 IGLV2-11(1-?) p-5Y-LAT-2 Ig heavy chain V-III region DOB Ig lambda chain V-I region VOR TXK VAV3 Ig lambda chain V-II region BOH Ig kappa chain V-I region HK101 IGLV3-22(1-?) CALM1IGKV2D-30 PLCG1 Ig kappa chain V-III region B6 PLCG1 Ig heavy chain V-II region NEWM RAC1 GRAP2 IGKV1-5(23-?) IGHV7-81(1-?) IGLC6 Ca2+ RELA p-13S-NFATC3 Ig lambda chain V-VI region AR p-10Y-LAT2 ATPIGLV1-44(1-?) Ig lambda chain V region 4A Ig lambda chain V-VI region AR Ig lambda chain V-VI region AR GRB2-1 MALT1 VAV2 Ig kappa chain V-I region AG IGHV1-2 Ub-124-UBB(77-152) Ig heavy chain V-II region MCE Allergin PPP3CB Ig kappa chain V-I region AG IGLC7 BTRC IGLV10-54(1-?) p-T325,T331,S362,S374-FOSSOS1 PI(3,4,5)P3 RAC1 TAB1:TAB2,TAB3:TAK1Ig kappa chain V-I region DEE Ig heavy chain V-III region BUT IGHV7-81(1-?) K63polyUbIg kappa chain V-III region B6 IGLC6 PI(3,4,5)P3RasGRPs:DAG:Ca2+IGLV1-44(1-?) IGLV4-60(1-?) Ig lambda chain V-VI region AR IGHV(1-?) Ig heavy chain V-III region KOL Ig lambda chain V-III region LOI IGHV(1-?) Ig kappa chain V-I region BAN Ig kappa chain V-I region Daudi Ig kappa chain V-III region POM IGLV3-25(1-?) PI(3,4,5)P3PPP3R1 p-Y239,Y240,Y317-SHC1-2 PSMD8 p-Y239,Y240,Y317-SHC1-2 Ig lambda chain V-I region HA JUNLCP2 Ig lambda chain V-IV region Bau p-FCERI aggregate p-S552,S645-CARD11 PI(3,4,5)P3 Ig kappa chain V-I region AG BCL10 oligomer IGKV1-5(23-?) IGLV3-12(1-?) DAGs IGLV3-25(1-?) BCL10 oligomer p-Y239,Y240,Y317-SHC1-2 Ig kappa chain V-II region Cum K63polyUb-TRAF6 IGLV7-46(1-?) Ig kappa chain V-I region Wes IGLV(23-?) Ig lambda chain V-III region SH MyrG-p-Y420-FYN p-5Y-LAT-2Ig heavy chain V-II region MCE PSMD3 Ig kappa chain V-I region DEE p-T202,Y204-MAPK3 PSMD13 p-Y223,Y551-BTK MALT1 oligomer p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3ATPIg lambda chain V-IV region Bau RASGRP2 IGLV3-22(1-?) IGKV4-1(21-?) PRKQC closedconformationGRAP2 Ig heavy chain V-III region DOB Ig lambda chain V-II region NEI p-Y90,T219,T538,S676,S695-PRKCQ IGLV(23-?) Zn2+ IGLV7-46(1-?) IGLV5-45(1-?) ADPSKP1 ATPPSMD1 ADPSOS1 IGLC1 TAB2 Fe3+ GRB2-1 PPP3CA IGKC p-Y239,Y240,Y317-SHC1-2 IGLV11-55(1-?) Ig lambda chain V-IV region Hil Ig heavy chain V-II region OU TXK IGKVA18(21-?) IGHE p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimerIg kappa chain V-III region VG GDP Ig kappa chain V-I region AU Ca2+ADPVAV2 PLCG2 VAV2 IGLV2-18(1-?) IGLV4-3(1-?) Ig kappa chain V-III region B6 IGLV3-27(1-?) DAGs IGLV5-37(1-?) Ig heavy chain V-II region MCE p-2Y-PAKIg heavy chain V-III region BUT UBE2V1 p-5Y-LAT-2 IGLV3-27(1-?) PSMA8 GRB2-1 IGLV3-12(1-?) PPP3CA Ig heavy chain V-III region CAM p-CARMA1 oligomer NAD+ NFKB1(1-433) Ig heavy chain V-III region DOB p-Y452,Y476,Y584-GAB2 p-Y113,128,145-LCP2 Ig lambda chain V-II region TOG DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:activated TAK1 complexFe3+ K63polyUb-TRAF6 Ig kappa chain V-II region RPMI 6410 VAV1 Ig kappa chain V-I region Gal AHCYL1 PPP3R1 p-10Y-LAT2 GTP SOS1 p-Y396-LYN CHUK Ig lambda chain V-II region BOH Ig kappa chain V-I region Gal NFKB1(1-433):RELAIGLV3-16(1-?) Allergin p-S271,T275-MAP2K7 Calcineurin (CaN)PLCG1 FCERI:IgE:allerginaggregateIGLC1 PI(3,4,5)P3 p-14S-NFATC2 MS4A2 p-Y113,128,145-LCP2 IGLV10-54(1-?) PIK3CA IGLC1 Ig heavy chain V-III region WEA p-S265-NFATC3 GRAP2 IKBKG p-5Y-LAT-2 PIP3, PI(3,4)P2IGLV1-40(1-?) IGLV3-25(1-?) Ig kappa chain V-I region DEE TRAF6 oligomer RASGRP4 RAC1:GDPPLCG1 p-Y113,128,145-LCP2 IGLC7 K63polyUb-NEMO p-Y519-TEC Ig lambda chain V region 4A Ig kappa chain V-III region VG SOS1 PSMB8 Ig lambda chain V-III region LOI GAB2SOS1 AMPp-5Y-LAT-2 Ig heavy chain V-III region TRO SYK/FYNp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCGADPIGLV5-37(1-?) DAGs NFAT:CaN:CaMAllerginPLCG2 Ig lambda chain V-I region NEWM p-5Y-LAT-2 p-S257-NFATC1 Ig lambda chain V-IV region Kern CHUK:IKBKB:IKBKGBCL10:MALT1Ig heavy chain V-II region NEWM p-Y551-BTK p-Y239,Y240,Y317-SHC1-2 IGKV2-28 IGKV3D-20 GAB2 PLCG1 PPP3R1 ITPR2 Ig kappa chain V region EV15 IGLV8-61(1-?) ITK PSMD7 RAF/MAP kinasecascadeIg heavy chain V-I region HG3 ITPR1 IGLV3-12(1-?) VAV2 IGLV7-43(1-?) Ig heavy chain V-III region BRO Ig kappa chain V-I region DEE IGLV3-16(1-?) GDPIg heavy chain V-III region KOL p-Y90,T219,T538,S676,S695-PRKCQ Ig lambda chain V-III region SH Ig kappa chain V region EV15 Ig heavy chain V-III region BUT IGKVA18(21-?) Ig heavy chain V-III region JON PSMB6 p-Y396-LYNATPIGLV3-22(1-?) p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2UBE2V1 Ig lambda chain V-II region NEI Ig lambda chain V-VI region AR IGLV7-46(1-?) Ig lambda chain V-II region NEI Fe3+ IGLV5-45(1-?) p-Y180,Y512-ITK IGLC6 IGLV2-11(1-?) p-FCERI aggregate Ig kappa chain V region EV15 IGLV1-40(1-?) IGLC6 Ig heavy chain V-III region WEA IgH heavy chain V-III region VH26 precursor Ig kappa chain V-II region RPMI 6410 IGLV4-3(1-?) IGLV1-40(1-?) ATPPLCG2 ADPIg heavy chain V-I region HG3 p-Y113,128,145-LCP2 PSMF1 Ig lambda chain V-II region MGC PSME3 RELA p-T,Y MAPK dimersIGLV3-27(1-?) CALM1:4xCa2+p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3p-2S-cJUN:p-2S,2T-cFOSp-CARMA1 oligomer IGLV2-23(1-?) p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCGp-5Y-LAT-2 p-10Y-LAT2 IGLV2-18(1-?) IGHV7-81(1-?) Ig heavy chain V-II region NEWM Ig lambda chain V-I region NEW MALT1 Ig heavy chain V-II region WAH ADPIGLV4-69(1-?) Ig kappa chain V-II region FR PPP3CA p-Y239,Y240,Y317-SHC1-2 Ig kappa chain V-III region B6 ATPPI(3,4,5)P3 VAV3 TAB3 IgH heavy chain V-III region VH26 precursor PSMB10 p-Y90,T219,T538,S676,S695-PRKCQ p-S257,T261-MAP2K4 S-Farn-Me PalmS NRAS PDK1:PIP2,PIP3PSMA2 Ub-48-UBB(1-76) UBE2N p-Y239,Y240,Y317-SHC1-2 p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76PSMA6 p-FCERI aggregate GRAP2 ADPCUL1 p-4Y-PLCG2 DAG:p-5Y-PKC-theta:p-S552,S645-CARMA1 oligomerIGLV10-54(1-?) I(1,4,5)P3 MALT1 oligomer GRAP2 Ig heavy chain V-I region EU p-Y113,128,145-LCP2 Ig kappa chain V-I region Gal Ig kappa chain V-I region Gal IGLV3-27(1-?) Ig kappa chain V-I region Wes DAGs GRB2-1 Ig kappa chain V-I region HK101 p-Y90,T219,T538,S676,S695-PRKCQ IGLV7-46(1-?) RELA Ig lambda chain V-II region NEI IGKV4-1(21-?) RELA ADPp-S243-NFATC2 SYKIg heavy chain V-III region TRO PRKCQ Ub-504-UBC(457-532) p-CARMA1 oligomer GRAP2 Ig kappa chain V-III region VG SOS1 p-S243-NFATC2 IGLV7-43(1-?) Ig heavy chain V-III region BRO PI(3,4,5)P3IGLV4-60(1-?) Ig heavy chain V-III region JON LAT-2IGLV4-3(1-?) IGLV2-33(1-?) IGKC Ig heavy chain V-II region NEWM Allergin GRB2-1 p-T,Y-MAPK8 Ig kappa chain V-I region BAN PIP3 activates AKTsignalingVAV1 Ig lambda chain V-I region VOR IGKV2-28 IGKV2D-30 IGLV4-69(1-?) MAP2K4Ig lambda chain V-III region SH Ig lambda chain V-IV region Kern DAGs BCL10 Ig heavy chain V-III region TRO IGLV1-40(1-?) p-10Y-LAT2 p-T325,T331,S362,S374-FOS ADPPI(3,4,5)P3 PLC gamma1,2Ig kappa chain V-I region HK101 IGLV3-16(1-?) p-S177,S181-IKBKB Ig kappa chain V-I region DEE GRB2-1 Ig heavy chain V-III region JON PiIGKV3D-20 IGKV3D-20 26S proteasomeIg kappa chain V-I region BAN PSMA7 IGLC6 IGLV7-46(1-?) IGLV10-54(1-?) ADPIGKV1-5(23-?) p-S177,S181-IKKB:IKKA:pUb-NEMONFKB1(1-433) IGLV8-61(1-?) LAT2IGLV2-33(1-?) ATPIGHV1-2 p-Y173-VAV3 IGKC IGKV2-28 DAG:p-5Y-PKC-theta:CBM oligomer:oligo-K63-poly Ub-TRAF6:TAK1:TAB1:TAB2/3p-FCERI aggregate GTP IGLV1-36(1-?) Ig lambda chain V-I region NEWM UBE2D2,UBE2D1,(CDC34)ADPGRAP2 Ig lambda chain V-II region NEI PSMC3 ITPR3 GRAP2 DAG:p-5Y-PKC-theta:CBM oligomerIGKV2D-30 IGLC7 SHC1-2PLCG2 IGKV3D-20 Ig heavy chain V-III region DOB IGLV3-16(1-?) IGLC2 ATPIg kappa chain V-I region Wes PLCG1 ADPIg heavy chain V-III region CAM p-S32,S36-NFKBIA CALM1 S-Farn-Me-PalmS KRAS4A p-Y113,128,145-LCP2 Ig kappa chain V-I region HK101 Ig kappa chain V-I region BAN Ig lambda chain V-I region NEW Ig heavy chain V-III region BUT IGHV1-2 VAV1 BTK p21 RAS:GTPCa2+ IGLV7-43(1-?) GDPIg heavy chain V-II region ARH-77 PAK1 Ig kappa chain V-I region Daudi IP3 receptorhomotetramerIGLV2-18(1-?) p-5Y-LAT-2 IGLV11-55(1-?) IGLV5-37(1-?) BTK Zn2+ Ig kappa chain V-I region Gal Ub-656-UBC(609-684) PSMB11 Ig heavy chain V-I region HG3 ATPIg kappa chain V-III region VG IGHV7-81(1-?) Ig kappa chain V-I region Wes ATPADPSOS1 Ig heavy chain V-I region EU PSMB9 VAV3 Allergin IGKV1-12 PI(3,4,5)P3 Ig heavy chain V-II region OU TAB1 GRB2-1 S-Farn-Me PalmS NRAS Ig heavy chain V-I region EU p-S265-NFATC3 Ub-48-UBA52(1-76) BCL10 oligomer Ig kappa chain V-II region RPMI 6410 IGKV1-5(23-?) IGKVA18(21-?) TAB3 p-Y174-VAV1 PIK3R2 Fe3+ ADPBCL10 oligomer IGLV2-11(1-?) ATPGRAP2 ADPIg lambda chain V-IV region Hil Ig lambda chain V-IV region Kern IgH heavy chain V-III region VH26 precursor Ig lambda chain V-I region HA ADPIGLV10-54(1-?) PPiDAG:p-5Y-PKC-theta:CBM complexp-SYK/p-BTKIGLV7-43(1-?) PSMA1 UBE2N:UBE2V1p-CARMA1 oligomer p-10Y-NTAL:p-SHC1:GRB2:SOS:GAB2IGLC2 IGKVA18(21-?) IGLV8-61(1-?) IGHV7-81(1-?) SOS1 PSME4 GRAP2 IGLV4-69(1-?) SOS1 p-S552,S645-CARD11Ig heavy chain V-III region BRO Allergin:p-LYN:p-FCERI:IgE aggregateIGLC3 ITPR3 IGLV1-36(1-?) p-5Y-LAT:p-SHC1:GRB2:SOS1PI(3,4,5)P3 S-Farn-Me-2xPalmS HRAS Clusteredp:LYN:p-FCERI:IgE:allergin:SYKIg kappa chain V-III region POM PDPK1 Ig lambda chain V-II region MGC PLCG2 Ig kappa chain V-I region AU Zn2+ PIK3R1 p-Y90,T219,T538,S676,S695-PRKCQ RASGRP1 IGLV3-25(1-?) Ig heavy chain V-III region CAM Ig lambda chain V-III region SH Ig heavy chain V-III region JON Allergin IGLC3 p-Y174-VAV1 IGLV1-36(1-?) PSMD12 IGHE PSMD14 Ig lambda chain V-I region HA IGLV11-55(1-?) MAP3K7 IGLV1-44(1-?) IGHV1-2 p-S257,T261-MAP2K4p-SHC1:GRB2:SOSp-BCL10 IGLV2-18(1-?) IGLV4-60(1-?) p-Y113,128,145-LCP2 DAGs p-5Y-LAT-2 Ig kappa chain V-II region Cum p-FCERI aggregate ATPPLCG1 SHFM1 IGHV1-2 p-S141,T402-PAK2 TAB1 Ig lambda chain V-III region SH UBE2N:UBE2V1IGLC2 Ig lambda chain V-II region MGC p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAVIg lambda chain V-IV region Hil CALM1 TAB2 IGKV1-12 Calcineurin:Calmodulin (CaN:CaM)Ig lambda chain V-II region MGC p-Y90,T219,T538,S676,S695-PRKCQ p-S271,T275-MAP2K7Ig heavy chain V-III region WEA IGLV5-37(1-?) Ca2+FCERI:IgE aggregate Ig lambda chain V-I region NEW IGLV3-12(1-?) Ig lambda chain V region 4A Ig kappa chain V-II region RPMI 6410 Ig kappa chain V-I region AU PDPK1MAP3K7 Ig heavy chain V-III region CAM MALT1 oligomer Ig kappa chain V-I region AG Ub-200-UBC(153-228) IGLV5-45(1-?) IGLV2-23(1-?) Ig heavy chain V-III region WEA Ig heavy chain V-III region KOL PLCG2 Ig heavy chain V-II region OU p-Y172-VAV2 p-Y90-PRKCQ Ig kappa chain V-II region Cum p-5Y-LAT-2 CARD11GRB2-1 p-CARMA1 oligomer Ig kappa chain V-II region FR PSMB7 PSMD10 ADPDAGs ITPR:I(1,4,5)P3tetramerIGLV1-36(1-?) IGKV2D-30 IGLV7-43(1-?) p-6Y-SYK UBE2N DAGs p-Y519-TEC p-10Y-NTAL:p-SHC1:GRB2:SOSIGLV3-25(1-?) PAK2 p-Y113,128,145-LCP2 H2Op-5Y-LAT-2 PI(3,4)P2 IGLV3-22(1-?) Ig heavy chain V-III region JON ADPDAGs p-Y420-TXK PKC-theta (open):DAGIg heavy chain V-II region ARH-77 Ig heavy chain V-II region MCE PSMC6 IGKC IGKV4-1(21-?) IGLV2-23(1-?) VAV1 DAGs Ig kappa chain V-I region Gal ATPIKBKB ADPPIK3CB PI(4,5)P2IGKV2D-30 PSMD11 K63polyUb-TRAF6 TAB1 PLCG2 IGLV2-33(1-?) Ig kappa chain V-II region Cum Ig lambda chain V-II region TOG IGLV7-43(1-?) Ig lambda chain V-I region NEWM PSMA3 Ig lambda chain V-I region NEWM p-5Y-LAT-2 DAGs Ig lambda chain V-II region MGC p-Y90,T219,T538,S676,S695-PRKCQ Ig heavy chain V-I region HG3 IGLC3 IGLV3-22(1-?) PPP3CB PSMC1 Ig heavy chain V-III region TRO IGLV4-60(1-?) Ig lambda chain V-II region NEI PSMB5 GRB2-1 SOS1 Ig lambda chain V-I region NEW Ub-352-UBC(305-380) p-MAPK8,9,10IGLV(23-?) Ig lambda chain V-IV region Kern Ig kappa chain V-II region RPMI 6410 DAG:p-5Y-PKC-theta:p-S552,S645-CARMA1IGKV1-5(23-?) VAV3 IGKV1-5(23-?) IGLV3-25(1-?) IGLV3-27(1-?) IGLV4-3(1-?) Ig kappa chain V-I region Wes IGLC3 IGHE IGKV4-1(21-?) p-S63,S73-JUN IGLV(23-?) RAC1 Ig lambda chain V-VI region AR PPP3CA Ig lambda chain V-III region LOI PAK dimerVAV2 Ig heavy chain V-III region WEA PI3Kp-Y396-LYN Ig kappa chain V-II region FR p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTPSOS1 GTPGRB2-1 IGLV(23-?) Ig lambda chain V region 4A p-6Y-SYK VAV1,2,3PPP3R1 IGLV3-12(1-?) p-Y90,T219,T538,S676,S695-PRKCQ IGHV1-2 CHUK IGLV11-55(1-?) Ig kappa chain V-I region Daudi IGLV4-69(1-?) RELA ATPIg lambda chain V-III region SH Ig kappa chain V-III region POM Ig lambda chain V-I region HA IGLV1-40(1-?) ITPR1 IGLV4-69(1-?) VAV1 p-Y239,Y240,Y317-SHC1-2 Ig heavy chain V-III region KOL p-Y396-LYN p-MAP2K4/p-MAP2K7GRB2-1 PAK2 NFKB1(1-433) p-Y420-TXK IGLV2-33(1-?) IGLV8-61(1-?) p-6Y-SYK p-CARMA1 oligomer PSME2 IGLV4-3(1-?) ATPCDC34 Ig lambda chain V-III region LOI MAP3K1p-S177,S181-IKBKB MALT1 oligomer ATP