Signaling by the B Cell Receptor (BCR) (Homo sapiens)

From WikiPathways

Jump to: navigation, search
5, 8, 10, 14, 25...8, 26, 29, 39, 120...131, 136, 140, 150, 16039, 144, 159, 1672722, 42, 107, 156, 16918, 94, 97, 12248, 57, 87, 91, 130...45, 77, 801, 35, 51, 52, 89...906, 15, 58, 71, 99...7, 38, 78, 81, 8845, 63, 16610, 85, 13495, 101, 11544, 53, 55, 83, 84, 139...5, 36, 37, 46, 61...12947, 69, 96, 145, 1709, 16, 124, 14647, 96, 17025, 61, 65, 92, 117...48, 57, 87, 91, 130...4524, 56, 73, 15262, 99, 102, 13811, 33, 68, 72, 98...13, 60, 74, 9010, 64, 85, 13421, 54, 14367, 77, 80, 135, 1663, 6, 15, 58, 105...17, 138, 15130, 34, 66, 148, 16012, 43, 82, 103, 108...1, 52, 89, 1094, 27, 40, 93, 111...20, 31, 125, 163, 168nucleoplasmplasma membranecytosolendoplasmic reticulum lumenIg lambda chain V-I region HA Ig kappa chain V region EV15 Ig lambda chain V-IV region Hil PSMB1 p-Y188,Y199-CD79A Ig kappa chain V-I region HK101 IGKV1-12 Ig heavy chain V-I region HG3 ADPIg lambda chain V-II region NEI IGHV1-2 Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:BTK:NCK1:VAV1:PLCG2Ig heavy chain V-III region BUT p-S265-NFATC3 p-Y188,Y199-CD79A PSMB3 Ig lambda chain V-I region VOR Ig lambda chain V-I region NEW Ig heavy chain V-II region NEWM p-4Y-PIK3AP1 Ig heavy chain V-III region BRO Ig lambda chain V-IV region Bau NFKBIB PTPN6:p-Y762,807,822-CD22:Antigen:p-BCRPSMB9 IGHV(1-?) SYKIg lambda chain V-III region LOI Ig kappa chain V-I region HK101 Ig heavy chain V-I region EU IGKV1-5(23-?) CD79A Ig kappa chain V-III region B6 Ig kappa chain V-I region AU Ig heavy chain V-III region BUT Ig kappa chain V-I region Wes Ig lambda chain V-II region TOG Ig heavy chain V-III region CAM p-12S-NFATC1 ADPIg kappa chain V-I region BAN ITPR3 ITPR3 HRAS Ig kappa chain V-I region Wes Ig heavy chain V-III region JON PSMD14 Ig kappa chain V-I region DEE Ig heavy chain V-III region KOL IGKV3D-20 PSME1 p-6Y-SYK BTRC Ig heavy chain V-II region OU Ig kappa chain V-III region POM Ig lambda chain V-II region TOG Ig heavy chain V-II region ARH-77 Ig heavy chain V-II region WAH IGLC2 IGLC1 PSIg kappa chain V-I region HK101 Ig kappa chain V-I region Gal Ig lambda chain V-I region NEW Ig lambda chain V-I region NEW p-5Y-BLNK Ig lambda chain V-I region VOR p-S559,S644,S652-CARD11 Ig kappa chain V-II region FR Ig kappa chain V-I region AU Ig lambda chain V-II region NEI Ig heavy chain V-II region NEWM Ig heavy chain V-III region JON MyrG2-PalmC3-LYN IGHM PSMD2 Ig heavy chain V-I region EU Ig kappa chain V-I region Daudi Ig kappa chain V-I region AU IGKV2D-30 IGKC Ig kappa chain V region EV15 Ig lambda chain V-IV region Bau IGHV7-81(1-?) Ig lambda chain V-III region SH RELA Ig kappa chain V-III region B6 Ig lambda chain V-III region LOI p-Y196,Y207-CD79B IKBKG Ig heavy chain V-III region CAM Ig lambda chain V-III region LOI Antigen Ig heavy chain V-II region MCE IGKV1-5(23-?) SH3KBP1 Ig lambda chain V-IV region Bau p-5Y-BLNK Ig lambda chain V-II region TOG Ig lambda chain V-II region BOH IGKV3D-20 Ig kappa chain V-II region Cum Ig lambda chain V-IV region Kern IGHD IGLC2 IGHV(1-?) Ig heavy chain V-II region ARH-77 Ig heavy chain V-III region BUT p-Y139-DAPP1:PLCG2:PIP3IGLC7 PSME2 IGLC6 IGLV(23-?) p-CD19:VAV1Ig kappa chain V-II region Cum Ig lambda chain V-I region NEWM ITPR1 IGLC3 NFKB1(1-433) IGHV1-2 Ig lambda chain V-III region SH IKBKG Ig heavy chain V-III region BRO p-S32,S36-NFKBIA PSMD8 Ig heavy chain V-II region NEWM VAV1 Ig lambda chain V region 4A PIK3CD ATPIg heavy chain V-III region BUT Ig lambda chain V-VI region AR Ig lambda chain V-I region VOR Ig heavy chain V-II region OU IGHV7-81(1-?) Ig kappa chain V-I region BAN Ig lambda chain V-I region NEW Ig lambda chain V-II region TOG UBB(1-76) Ig kappa chain V-I region Gal ATPIg kappa chain V-II region RPMI 6410 IGKV2D-30 SH3KBP1 IGHV7-81(1-?) Ig lambda chain V-I region NEW IGKV1-12 p-6Y-CD19 p-Y196,Y207-CD79B IGHD IGKVA18(21-?) Antigen PIK3CD:PIK3R1Ig kappa chain V-II region Cum IGKV3D-20 Ig heavy chain V-III region DOB IGKV4-1(21-?) p-Y188,Y199-CD79A IGKC Ig kappa chain V-II region Cum IGLC3 p-Y762,807,822-CD22:Antigen:p-BCRIg lambda chain V-II region NEI Ig lambda chain V-III region LOI Ig heavy chain V-III region BRO Ig lambda chain V-I region NEWM Ig heavy chain V-II region MCE Ig lambda chain V-II region BOH PPP3R1 Ig lambda chain V-I region VOR Ig kappa chain V-I region HK101 Ig heavy chain V-II region MCE AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramerSOS1 Antigen:p-BCRIgH heavy chain V-III region VH26 precursor Ig heavy chain V-III region BRO UBC(77-152) ADPGRB2-1 Ig kappa chain V-I region HK101 PSMA1 GRB2-1 IGLC3 IGKV4-1(21-?) CD79A p-T184-RASGRP1 Ig kappa chain V-I region Gal GRB2-1ITPR:I(1,4,5)P3tetramerIg lambda chain V-II region TOG IGKV2-28 p-5Y-BLNK PRKCB Ig kappa chain V-I region AG Ig lambda chain V-IV region Kern Ig heavy chain V-III region KOL REL Ig kappa chain V-I region Daudi Ig heavy chain V-III region JON ATPPSME3 Ig heavy chain V-III region TRO Ig kappa chain V-II region FR Ig kappa chain V-I region AU Ig kappa chain V region EV15 Ig kappa chain V-I region AG NRAS CALM1 Ig lambda chain V-III region LOI PTPN6 BCRp-5Y-BLNK GTP Ig kappa chain V-I region Wes Ig kappa chain V region EV15 Ig kappa chain V-I region AG IGKV1-12 Ig heavy chain V-III region KOL IGHM IGLC7 ITPR1 IGHV1-2 p-S559,S644,S652-CARD11 Ig kappa chain V-I region DEE Ig lambda chain V-IV region Kern Ig lambda chain V-I region NEWM Ig lambda chain V-II region NEI Ig kappa chain V-I region AU CUL1 ORAI dimerIg kappa chain V-I region Daudi Ig heavy chain V-I region EU IGLC6 Ig kappa chain V-I region HK101 Ig kappa chain V-III region VG IGLC6 LYN,FYN,BLKIg heavy chain V-I region HG3 NAc-CD22Ig lambda chain V-I region NEW Ig heavy chain V-II region ARH-77 CALM1 Ca2+ Ig kappa chain V-I region Gal Ig kappa chain V region EV15 Ig kappa chain V-I region Daudi Ig lambda chain V-III region LOI Ig heavy chain V-II region MCE IGHM Ig lambda chain V-I region NEW Ig kappa chain V-II region Cum Ig lambda chain V-IV region Bau Ig lambda chain V-I region NEW ADPGRB2-1 ADPIg lambda chain V-II region TOG Ig lambda chain V-II region BOH PSMA4 Ig lambda chain V-I region VOR Ig kappa chain V-II region Cum IGKVA18(21-?) Ig heavy chain V-III region BRO IGKV2-28 Ig lambda chain V-II region BOH Antigen Ig heavy chain V-III region BUT Ig heavy chain V-I region HG3 p-14S-NFATC2 Ig kappa chain V-I region Gal IGKC IGLC2 DAPP1PSMD12 IGKV1-12 IGLC6 IGLC3 Ig heavy chain V-III region WEA ADPIg lambda chain V-I region HA IgH heavy chain V-III region VH26 precursor ITPR2 IgH heavy chain V-III region VH26 precursor Ig heavy chain V-III region JON IGHV7-81(1-?) Ig lambda chain V-II region NEI ADPAHCYL1 Ig kappa chain V-II region Cum Ig kappa chain V-I region HK101 IGHV(1-?) Ig heavy chain V-II region NEWM Ig kappa chain V-I region AG PI(4,5)P2IGLC2 SOS1 ORAI1 Activated PKC betaNCK1IgH heavy chain V-III region VH26 precursor Ig kappa chain V-I region HK101 Ig kappa chain V-II region Cum Ig lambda chain V-II region NEI UbIg lambda chain V-III region SH Ig heavy chain V-III region KOL IGKV1-5(23-?) IGHD p-Y753,Y759,Y1217-PLCG2 Ig kappa chain V-III region POM IGKVA18(21-?) PIK3CD Ig kappa chain V-I region DEE PLCG2 IgH heavy chain V-III region VH26 precursor CD19 SignalosomeIGHV7-81(1-?) RPS27A(1-76) UBC(305-380) IGLV(23-?) PSMD7 IGKV3D-20 Ig heavy chain V-II region ARH-77 NAc-CD22homo-oligomerORAI1 IGLC6 Ig heavy chain V-I region EU Ig lambda chain V-IV region Hil ATPIg kappa chain V-I region BAN Ig kappa chain V-I region DEE MALT1 Ig lambda chain V-I region NEW GRB2-1 Ig kappa chain V-II region Cum Ig lambda chain V-I region HA Ig heavy chain V-III region TRO p-14S-NFATC2 Ig kappa chain V-II region FR IGKV2D-30 Ig heavy chain V-II region WAH IGLC3 PRKCBIg kappa chain V region EV15 Ig heavy chain V-II region WAH Ig kappa chain V-II region RPMI 6410 IGHV7-81(1-?) Ig heavy chain V-III region TRO MALT1 Ig lambda chain V-IV region Bau IGHV1-2 Ig lambda chain V-I region VOR NFKB1(1-433) p-T133-RASGRP3 Fe3+ Ig heavy chain V-III region BRO IGHD Ig heavy chain V-II region ARH-77 Ig lambda chain V-VI region AR MyrG2-BLK p-Y188,Y199-CD79A Ig heavy chain V-III region CAM Ig lambda chain V-IV region Kern Ig heavy chain V-III region CAM IGHV7-81(1-?) IGKV2D-30 p-4Y-PIK3AP1Ca2+ Ig heavy chain V-III region WEA Antigen:p-BCR:SYKIg kappa chain V-III region B6 Ig kappa chain V-II region RPMI 6410 MAP3K7 PhosphorylatedNFATC1,2,3Ig heavy chain V-I region HG3 SH3KBP1 IGKV1-5(23-?) IGHM p-S19,S23-NFKBIB Ig heavy chain V-I region EU IKBKB Ig heavy chain V-III region DOB ATPp-Y196,Y207-CD79B Ig heavy chain V-I region EU IGLC7 p-5Y-BLNK Ig heavy chain V-III region BRO IGLC3 DAGp-CARMA1:MALT1:p-BCL10:TAK1STIM1 DimerIGKV4-1(21-?) p-S157,S161-Ub-NFKBIE IGLV(23-?) Ig heavy chain V-III region CAM Ig heavy chain V-III region WEA IGHM IGLC3 Ig kappa chain V-I region BAN UBC(381-456) IGHV1-2 IGKV4-1(21-?) Ig lambda chain V-I region NEWM PIK3R1 Antigen Ig kappa chain V-III region B6 PLCG2 GDPIg kappa chain V-I region Daudi Ig lambda chain V-II region BOH Ig kappa chain V region EV15 Ig kappa chain V-III region POM p-Y762,807,822-CD22 Ig lambda chain V-IV region Hil Ig lambda chain V region 4A UBC(229-304) Ig lambda chain V-IV region Bau IGKV1-5(23-?) Ig lambda chain V-VI region AR Ig heavy chain V-III region BRO RELA Ig heavy chain V-II region OU PSMD1 Ig heavy chain V-II region NEWM Ig heavy chain V-II region WAH Ig lambda chain V-II region NEI GRB2-1 Ig heavy chain V-II region MCE Ig kappa chain V-I region AU Ig lambda chain V-IV region Kern Ig lambda chain V-II region MGC RELA Tacrolimus Ig kappa chain V-I region AG Ig heavy chain V-II region OU Ig heavy chain V-III region BUT IGHV7-81(1-?) ITPR3 Ig heavy chain V-III region BRO Ig kappa chain V-I region Gal Ig heavy chain V-I region EU Ig heavy chain V-III region KOL PSMB11 CARD11 VAV1 Ig heavy chain V-III region JON Ig lambda chain V-III region SH Ig lambda chain V-IV region Hil Ig lambda chain V-VI region AR Ig heavy chain V-I region HG3 GTPVAV1 IGHV7-81(1-?) Ig lambda chain V-II region TOG IGLC7 IGHM IGLC1 NF-kappaBp50,p65,c-Rel dimerCalcineurin:Phosphorylated NFATC1,2,3Ig lambda chain V-VI region AR Ig lambda chain V-II region MGC IGLC1 UBC(153-228) PSMB8 ATPIg kappa chain V-III region POM Ig kappa chain V-II region FR Ig lambda chain V-III region SH PI(3,4,5)P3 IGHM Ig heavy chain V-III region BUT UBC(609-684) Ig kappa chain V-III region VG Ig heavy chain V-I region HG3 Ig kappa chain V-I region BAN Ig lambda chain V-II region TOG p21 RAS:GTPIg lambda chain V-I region VOR Ig kappa chain V-III region B6 IGKV1-12 Ig heavy chain V-III region WEA CyclophilinA:Cyclosporin AIGHM IgH heavy chain V-III region VH26 precursor Ig kappa chain V-I region AG IGKV4-1(21-?) Ig kappa chain V-I region Wes p-6Y-SYK Ig kappa chain V-III region VG Ig kappa chain V-III region B6 Ig heavy chain V-III region BRO Ig heavy chain V-III region DOB IGLC2 Ig kappa chain V-III region B6 IGKV3D-20 Ig lambda chain V-III region LOI Ig kappa chain V-I region Daudi Ig heavy chain V-I region HG3 Ig lambda chain V-I region VOR Ig heavy chain V-III region JON Ig lambda chain V-I region VOR Ig kappa chain V-II region FR p-Y196,Y207-CD79B VAV1 UBB(153-228) IGKV1-12 IGHV7-81(1-?) Ig lambda chain V-II region MGC Ig lambda chain V-I region NEW 26S proteasomeIGKC UBB(77-152) PSMB4 Ig kappa chain V-I region DEE Ig kappa chain V-I region BAN STIM1:CalciumIGKV2D-30 Ig heavy chain V-II region ARH-77 Ig heavy chain V-II region ARH-77 IGLV(23-?) MAP3K7 IGLV(23-?) Ig kappa chain V-III region VG ADPIg kappa chain V-I region BAN Ig heavy chain V-II region ARH-77 Ig lambda chain V-I region NEWM IGKVA18(21-?) Ig lambda chain V-I region VOR IGKV2-28 IGHV1-2 Ig heavy chain V-III region JON REL UBA52(1-76) IGLC1 Ig kappa chain V-I region Daudi p-13S-NFATC3 PSMA2 PSMB6 PPP3CA Ig heavy chain V-III region JON Ig kappa chain V-I region DEE Ig heavy chain V-I region EU Ig lambda chain V-IV region Bau IGLV(23-?) IGKV2-28 NFKB1(1-433) Ig lambda chain V-II region BOH Ig kappa chain V-I region Gal PSMB10 IGLC7 ADPREL IGLC7 p-5Y-BLNK IGKV1-12 IGKV2D-30 Ig kappa chain V-I region Gal p-6Y-SYK Ig lambda chain V-IV region Bau Ig heavy chain V-III region KOL Ig lambda chain V-II region BOH Ig heavy chain V-I region HG3 IgH heavy chain V-III region VH26 precursor Ig lambda chain V-IV region Kern Antigen:BCRIg lambda chain V-I region HA IGHD Ig kappa chain V-III region POM Ig heavy chain V-III region JON Ig kappa chain V-I region AU Ca2+ Antigen Ig lambda chain V-I region HA IGKV4-1(21-?) Ig kappa chain V-I region DEE IGLV(23-?) Ig lambda chain V-IV region Hil IGKC Ig kappa chain V-II region Cum IGKV3D-20 Ig kappa chain V-I region Daudi IGLC2 Ig lambda chain V-I region NEW Ig kappa chain V-III region POM Ig kappa chain V-I region DEE Ig heavy chain V-III region CAM Ig lambda chain V-III region SH Ig heavy chain V-II region MCE VAV1 IGHM UBC(1-76) p-BCL10 Ig lambda chain V region 4A IGHD Ig kappa chain V-III region POM Ig kappa chain V region EV15 Ig lambda chain V-III region LOI p21 RAS:GDPGDP Ig lambda chain V-I region HA Ig heavy chain V-III region TRO IGKV2D-30 Ig lambda chain V-IV region Bau PI(4,5)P2Ig kappa chain V-I region AG RELA PPP3CA Ig heavy chain V-II region OU SKP1 CD22Ig heavy chain V-II region NEWM ADPIGKV2-28 Ig lambda chain V-I region HA p-S157,S161-NFKBIE BLNK:GRB2:SOS1:CIN85Ig heavy chain V-II region WAH Ig lambda chain V-II region BOH Ig heavy chain V-II region OU Ig kappa chain V-III region B6 Antigen IGKC Ig kappa chain V-I region BAN IGHV7-81(1-?) Ig lambda chain V-III region LOI IGLC1 IGLC7 Ig heavy chain V-II region ARH-77 Ig lambda chain V-I region HA Ig lambda chain V-I region VOR Ig heavy chain V-III region DOB IGKC IGLV(23-?) ORAI2 IGHD GRB2-1 IGKV3D-20 HRAS IGLC7 IGLV(23-?) Ig heavy chain V-II region WAH IGKV2-28 BTKCD19:VAV1IGHD IGLC7 IGLC1 ATPIg lambda chain V-IV region Hil IGHV(1-?) IGKV4-1(21-?) IGHV7-81(1-?) IgH heavy chain V-III region VH26 precursor IGLV(23-?) p-Y139-DAPP1 Ig heavy chain V-II region OU IGKV2-28 PSMC2 Ig kappa chain V-III region VG Ig kappa chain V-II region RPMI 6410 p-CARMA1 OligomerREL Ig heavy chain V-III region KOL CARMA1 oligomerIg kappa chain V-III region B6 Ig kappa chain V-II region RPMI 6410 Ig heavy chain V-III region BUT NFKB1(1-433) Ig heavy chain V-III region CAM IGHM IGKVA18(21-?) Ig lambda chain V-II region MGC IGKV1-12 Ig kappa chain V-I region HK101 Ig kappa chain V-I region Gal IGKV1-12 Ig heavy chain V-III region DOB Ig heavy chain V-III region TRO IGKV2-28 IGLC7 IGKV2D-30 MyrG2-PalmC3-LYNPLCG2Ca2+ Ca2+IGKV2D-30 Ig heavy chain V-III region TRO IGLC3 Ig lambda chain V-IV region Kern PSMD13 SOS1 Ig lambda chain V-II region MGC Ig lambda chain V-II region NEI Ig lambda chain V-I region NEWM Ig lambda chain V-IV region Hil CUL1 IGKC p-BCL10IGKV2-28 CHUK IGLC3 NFKBIA p-Y188,Y199-CD79A Antigen Ig lambda chain V region 4A Ig kappa chain V region EV15 PSMD11 STIM1:TRPC1IGKC IGHV7-81(1-?) p-Y196,Y207-CD79B Ig heavy chain V-III region TRO Ig lambda chain V-IV region Hil NFKB1(1-433) Ig lambda chain V-IV region Bau SYK IGKV4-1(21-?) STIM1 ADPIgH heavy chain V-III region VH26 precursor Ig kappa chain V-III region B6 PS IGKV3D-20 Ig lambda chain V-III region LOI Ig kappa chain V-III region VG IGKV3D-20 Ig kappa chain V-I region Wes IGLC6 IGKV3D-20 Ig heavy chain V-III region BRO Ig lambda chain V-II region BOH IgH heavy chain V-III region VH26 precursor SOS1 Ig lambda chain V-VI region AR IGLC1 Ig kappa chain V-I region BAN PI(3,4,5)P3 Ig kappa chain V region EV15 Ig heavy chain V-II region ARH-77 FKBP1A Ig lambda chain V-I region NEW Ig heavy chain V-I region HG3 IGKV1-5(23-?) Ig kappa chain V-I region Gal IGHV(1-?) Ig lambda chain V-IV region Hil I(1,4,5)P3SH3KBP1 IGLC2 PSMB2 Ig lambda chain V-VI region AR Ig lambda chain V-II region TOG SH3KBP1 Ig lambda chain V-II region NEI Calcineurin (CaN)p-Y188,Y199-CD79A Ig heavy chain V-III region TRO NCK1 Ig heavy chain V-II region OU IGLC7 Ig heavy chain V-III region BUT IGHV(1-?) CD19 Ig kappa chain V-III region POM SH3KBP1 Ig kappa chain V-I region Gal Ig kappa chain V-II region RPMI 6410 Ig lambda chain V-I region NEWM ATPBLNK IGKV3D-20 Ig heavy chain V-II region NEWM REL MALT1p-BCL10 KRAS Ig lambda chain V-I region NEW PSMD5 Ig heavy chain V-III region WEA IGLC7 Ig heavy chain V-III region CAM Ig lambda chain V-IV region Kern PI(3,4,5)P3 Ig heavy chain V-III region CAM Ig heavy chain V-II region WAH IGKC IGHV7-81(1-?) Antigen:p-BCR:p-SYKMyrG2-PalmC3,6-FYN PIK3R1 Ig lambda chain V-I region HA IGKV2D-30 Ig heavy chain V-I region EU Ig heavy chain V-III region WEA IGHV1-2 PSMA7 IGLV(23-?) SOS1 REL p-S32,S36-NFKBIA p-BCL10 Ig lambda chain V-II region TOG Ig kappa chain V-III region B6 Ig kappa chain V-I region HK101 p-CARMA1:MALT1:p-BCL10:TAK1:IKKBTRC Ig kappa chain V-I region Gal Ig kappa chain V-II region FR PPP3CB NCK1 Ig lambda chain V-VI region AR Ig lambda chain V-IV region Hil Ig lambda chain V region 4A Ca2+Ig kappa chain V-III region POM IGLC2 p-Y188,Y199-CD79A NF-kappaB:p-IkB:SCF-betaTrCPIg kappa chain V-I region AG Ig kappa chain V-I region DEE PLCG2 Ig heavy chain V-III region TRO Ig lambda chain V-III region LOI p-S19,S23-NFKBIB p-Y188,Y199-CD79A IGKV1-5(23-?) STIM1 Cyclosporin A Ig kappa chain V-I region Daudi SHFM1 STIM1 Ig heavy chain V-II region WAH Ig kappa chain V-II region Cum Ig lambda chain V-II region MGC IGHD ATPIg heavy chain V-III region BRO ORAI2 BLNK (SLP-65)Signalosomep-Y188,Y199-CD79A Ig heavy chain V-I region EU SOS1 Ig lambda chain V region 4A PI(3,4,5)P3 IGHV1-2 IGKV2-28 IGHV(1-?) p-S559,S644,S652-CARD11 DAG PI(3,4,5)P3 IGLC1 IGKV4-1(21-?) Ig heavy chain V-III region DOB Ig kappa chain V-I region Wes IGLC2 IGKVA18(21-?) Ig kappa chain V-I region BAN Ig lambda chain V-II region NEI IKBKG IGKV3D-20 IGLC2 PSMD3 PSMA3 Ig heavy chain V-III region JON p-Y196,Y207-CD79B PSMC1 Ig heavy chain V-II region MCE Ig heavy chain V-III region KOL IGLC7 Ig heavy chain V-I region HG3 Ig heavy chain V-III region WEA PIP3 activates AKTsignalingIg kappa chain V-I region AU PPP3CB IGKV1-5(23-?) p-S559,S644,S652-CARD11 IGKV2-28 Ig lambda chain V-II region NEI Ig lambda chain V-II region TOG IGKC Ig lambda chain V-II region MGC IGLC1 Ig heavy chain V-III region CAM RELA Ig heavy chain V-II region NEWM Ig heavy chain V-II region NEWM Ig lambda chain V-III region SH IGLC1 Ig heavy chain V-III region JON Ig kappa chain V-I region Wes Ig kappa chain V-II region FR RASGRP3 Ig lambda chain V-II region TOG Ig lambda chain V-III region SH p-Y762,807,822-CD22 IGKV3D-20 GRB2-1 Ig lambda chain V-III region LOI DephosphorylatedNFATC1,2,3Ig heavy chain V-II region OU Ig kappa chain V-I region Wes IGHV1-2 ITPR1 ATPNFKB1(1-433) IGLC7 Ig heavy chain V-I region EU IGHD Ig kappa chain V-I region Daudi Ig kappa chain V-III region VG PPIA Ig heavy chain V-III region BRO Ig kappa chain V-II region Cum IGHD Ig lambda chain V-II region TOG Ig lambda chain V-I region HA Ig lambda chain V-VI region AR Ig kappa chain V-I region BAN Ig heavy chain V-II region WAH p-6Y-SYK Ig heavy chain V-I region HG3 Ig lambda chain V-IV region Bau Ig lambda chain V-I region HA BCAP SignalosomeIg lambda chain V-IV region Hil Ig heavy chain V-III region TRO Ig heavy chain V-III region DOB IGKV1-12 Ig heavy chain V-II region WAH Ig kappa chain V-I region BAN Ig heavy chain V-III region TRO Ig kappa chain V-I region AU Ig lambda chain V-III region SH Ig kappa chain V region EV15 IGKVA18(21-?) Ig heavy chain V-III region WEA Ig heavy chain V-III region BUT Ig kappa chain V-II region FR IGLC6 Ig heavy chain V-III region KOL Ig lambda chain V-I region NEWM IGKV4-1(21-?) NCK1 Ig kappa chain V-I region HK101 IGKV4-1(21-?) Ig kappa chain V-I region Gal Ig lambda chain V region 4A Ig heavy chain V-III region WEA IGKV1-12 IGLC6 Ig heavy chain V-I region EU Ig heavy chain V-II region WAH Ig heavy chain V-III region BUT PSME4 Ig lambda chain V region 4A Ig lambda chain V-IV region Bau Ig heavy chain V-II region OU p-Y196,Y207-CD79B Ig heavy chain V-II region MCE Ig kappa chain V-II region RPMI 6410 AntigenIg heavy chain V-II region MCE Ig heavy chain V-II region WAH Ig lambda chain V-II region MGC Ig lambda chain V-II region MGC IGKV4-1(21-?) FKBP1A:TacrolimusCD22:Antigen:p-BCRp-Y223,Y551-BTK Ig lambda chain V-VI region AR IGHM IgH heavy chain V-III region VH26 precursor p-Y196,Y207-CD79B Ig lambda chain V region 4A I(1,4,5)P3 p-Y196,Y207-CD79B CD22 Ig lambda chain V-IV region Bau Ig lambda chain V-I region HA p-13S-NFATC3 IGLC2 IGKV1-12 Ig kappa chain V-II region RPMI 6410 Ig heavy chain V-III region BRO IP3 receptorhomotetramerp-CARMA1:MALT1:p-BCL10IGLC6 IGKVA18(21-?) IGHV(1-?) Ig heavy chain V-II region ARH-77 Ig lambda chain V-IV region Kern ITPR2 Ig lambda chain V-VI region AR Ig lambda chain V-I region NEWM Ig lambda chain V-IV region Kern Ig kappa chain V-I region DEE Ig kappa chain V-III region VG VAV1 Ig heavy chain V-II region WAH Ig kappa chain V-I region Daudi GRB2-1 Ig lambda chain V-I region NEWM p-Y223,Y551-BTK Ig kappa chain V-III region VG p-6Y-SYK Ig heavy chain V-III region WEA Zn2+ Ig kappa chain V-I region AG Ig kappa chain V region EV15 Ig kappa chain V-I region Wes Ig heavy chain V-I region HG3 PSMB7 PSMC5 Ig heavy chain V-II region OU IGLC6 Ig heavy chain V-III region JON Ig kappa chain V-I region DEE Fe3+ Ig kappa chain V-I region BAN IGLC6 Ig heavy chain V-II region OU Ub-21,22-p-S32,S36-NFKBIA PSMA8 PSMC4 p-6Y-CD19 PI(3,4,5)P3 Ig heavy chain V-III region BUT NRAS CALM1:4xCa2+ADPIg kappa chain V-I region Wes p-Y188,Y199-CD79A IGHV(1-?) Antigen Ig heavy chain V-II region NEWM Ig kappa chain V-III region POM SH3KBP1 IGLC1 PI(3,4,5)P3IGKV2D-30 Ig kappa chain V-II region RPMI 6410 p-6Y-SYK p-S177,S181-IKBKB LYN, p-SYKNFKBIE Ig kappa chain V-II region RPMI 6410 Ig kappa chain V-III region B6 SOS1 Ig heavy chain V-III region TRO Ig lambda chain V-II region MGC PSMC3 Ig kappa chain V-I region Gal IgH heavy chain V-III region VH26 precursor Ig kappa chain V-III region POM Ig kappa chain V-I region AG Ig lambda chain V-II region BOH NF-kappa-Bp50,p65,c-Rel:p-IKBIg lambda chain V-II region TOG VAV1Ig heavy chain V-III region CAM Ig kappa chain V-I region Wes Ig lambda chain V-IV region Kern Ig heavy chain V-III region WEA IGKV2-28 Ig lambda chain V-I region VOR TRPC1 IGLC3 IGLC3 IGLC1 Ig kappa chain V-II region RPMI 6410 NCK1 Ig lambda chain V region 4A Ig kappa chain V-I region Daudi IgH heavy chain V-III region VH26 precursor IGLV(23-?) Ig kappa chain V-I region HK101 CD79B Ig kappa chain V-II region FR BTK Ig kappa chain V-III region VG Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y223,Y551-BTK:NCK1:VAV1:PLCG2IGHV1-2 IGKV2D-30 Ig heavy chain V-III region CAM Ig kappa chain V-II region RPMI 6410 IGHV(1-?) Ig lambda chain V-IV region Hil Ig heavy chain V-III region CAM Ig heavy chain V-III region JON Ig kappa chain V-III region POM Ig heavy chain V-III region JON SKP1 p-Y188,Y199-CD79A p-Y139-DAPP1 CHUK Ig lambda chain V-I region HA IGHM NF-kappa-Bp50,p65,c-Rel:IKBIg lambda chain V region 4A MALT1 TRPC1Ig kappa chain V-I region BAN MAP3K7Ig heavy chain V-III region WEA Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1:p-Y551-BTK:NCK1:VAV1:PLCG2IGLV(23-?) Ig lambda chain V-II region BOH Ig heavy chain V-II region NEWM Ig heavy chain V-III region DOB Ig lambda chain V-II region BOH Ig heavy chain V-I region EU p-S19,S23-Ub-NFKBIB Ig kappa chain V-I region HK101 PPP3R1 IGHV1-2 Ig kappa chain V-I region AG p-6Y-SYK Ig kappa chain V-II region FR p-12S-NFATC1 IGKV2D-30 p-Y196,Y207-CD79B ATPIg lambda chain V-I region NEW ATPITPR2 NF-kappaBp50,p65,c-Rel:ub-p-IKBIg kappa chain V-III region VG IGKV2D-30 PSMD10 Ig heavy chain V-I region HG3 Ig kappa chain V-II region Cum Ig heavy chain V-III region KOL PIK3CD IGKVA18(21-?) Ig heavy chain V-II region MCE IGLC6 Ig lambda chain V region 4A Ig kappa chain V-I region Daudi Ig kappa chain V-I region DEE Ig kappa chain V-I region DEE Ig heavy chain V-II region MCE Ig kappa chain V-I region AU UBC(457-532) IGHV(1-?) IGKV1-12 Ig lambda chain V-I region NEWM PLCG2 IGHM FBXW11 Ig kappa chain V-I region Wes Ig heavy chain V-II region MCE PSMB5 CRAC channelATP(BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1)Antigen Ig kappa chain V-III region VG IGKV3D-20 IGHV(1-?) IGKV1-5(23-?) Ig lambda chain V region 4A Ig kappa chain V-I region Wes IGKV1-12 Ig heavy chain V-III region TRO PSMA5 Ig kappa chain V-II region RPMI 6410 RASGRP1,3Ig heavy chain V-II region MCE IGKVA18(21-?) IGHV1-2 IGKV1-5(23-?) IGKV1-5(23-?) Ig lambda chain V-II region NEI Ig heavy chain V-II region ARH-77 IGHV1-2 p-Y551-BTK Ig heavy chain V-III region CAM IGLC2 Ig lambda chain V-VI region AR Ig heavy chain V-II region ARH-77 Ig kappa chain V region EV15 Antigen:p-BCR:p-SYK:p-BLNK:CIN85:GRB2:SOS1IGHV(1-?) Ig kappa chain V-I region Daudi Ig lambda chain V-III region SH Ig lambda chain V-IV region Kern PTPN6Ig lambda chain V-III region LOI VAV1 Ig heavy chain V-III region DOB Ig heavy chain V-III region WEA IGHD Ig lambda chain V-VI region AR Ig kappa chain V-I region Wes IGKV1-5(23-?) Ig kappa chain V-II region FR Ig lambda chain V-III region SH MyrG2-PalmC3-LYN Ig lambda chain V-I region VOR KRAS