Extracellular matrix organization (Homo sapiens)

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16, 26, 5410, 20, 48, 56, 64...4, 35, 785, 14, 37, 44, 6850, 6731, 60, 7932, 4372, 78114762124529, 51, 58, 761824, 49, 53653, 13, 28, 3015, 21, 25, 39, 59...46, 6719, 27, 36, 41702786617942, 5574638, 3852cytosol3x4Hyp-3Hyp-5Hyl-COL9A2 GalHyl-COL9A2 DAG1(654-895) Collagen type III fibril SPARCDegradation of theextracellularmatrixDCNADAM12,ADAM15,ADAM19TGFB1 Collagen type X fibril LAMC1 3x4Hyp-GlcGalHyl-COL9A3 DAG1(654-895) 3x4Hyp-3Hyp-COL9A1 Collagen type IV alpha3.alpha4.alpha5 network Collagen type IV alpha3.alpha4.alpha5 network FN1(32-2386):Collagen types I-V, VIICollagen type IV alpha1.alpha2.alpha5.alpha6 network HA FN1(32-2386) DDR1 LAMB2 GlcGalHyl-COL9A1 AGRN(30-2045) GlcGalHyl-COL9A2 SLRPsADAM12 Collagen type I, II,III, VI fibrilsHSPG2(22-4391) Integrinalpha6beta1:Laminin-211, 221, 332, 411, 512, 521LAMB1 LAMB1 Collagen type VI fibril AGRN(30-2045) ITGAV(31-1048) Collagen type I fibril ITGB1 ITGA1 LAMA5 LAMC1 SPARC Collagen type II fibril Collagen type I fibril AggrecanLAMA2 Integrin alpha2beta1LAMC2 LAMB1 GlcGalHyl-COL9A3 C6S-BGN LAMC2 FN1(32-2386)HACollagen V AGRN, HSPG2TGF betaLAMB2 IntegrinsalphaVbeta1,alphaVbeta3,alphaVbeta5,alpha2bbeta3HSPG2(22-4391) Collagen IV Collagen formationNTN4Laminin-332LAMB1 LAMA2 LAMC1 LAMA3 NTN4 VTN DCN:Collagen type I,II, III, VI fibrilsLAMA5 3x4Hyp-3Hyp-5Hyl-COL9A3 Collagen typeI,IV,VIIntegrin cellsurfaceinteractionsITGB1 LAMC1 Collagen type VII fibril 3x4Hyp-3Hyp-GalHyl-COL9A3 3x4Hyp-GalHyl-COL9A1 Collagen V ITGB1 Laminin networkDSPP(463-1301) IBSP DAG1(30-653) ADAM19 DDR2 dimerLAMA2 Collagen type III fibril NCAM1 SH3PXD2A LAMA4 ITGA2B(32-1039) LAMA2 LAMB2 HydroxylapatiteLAMC1 GalHyl-COL9A3 5Hyl-COL9A3 Integrinalpha5beta1:Fibronectin matrixCollagen type II fibril LAMB1 COL18A1(1572-11754) NRXN1 SulfatideLAMC3 BGN 3x4Hyp-3Hyp-5Hyl-COL9A1 LAMA2 Collagen type I, II,III, V, X fibrilsCollagen IV ITGA5(42-894) Fibronectin matrixLAMB2 Collagen type I fibril GlcGalHyl-COL9A1 Collagen type IV alpha1.alpha1.alpha2 network Laminin-211, 221,332, 411, 512, 521TNN MATN3 Sulfatide ITGB1 ITGA6(24-1130) LAMB1 LAMC1 COL9A2 TTR VTN DMD KS(2),C6S-ACAN ITGA5(42-894) LAMA2 ADAM15 LAMA4 LAMB3 NID1 KS(2),CSE-ACAN KS(2),C4S-ACAN Collagen V LAMC3 ITGB3 Mn2+COMP LAMA1 Collagen type IV alpha3.alpha4.alpha5 network ITGA2 ITGB1 KS(2)-FMOD SH3PXD2A:PI(3,4)P2IntegrinalphaVbeta3,alphaVbeta6,alpha2beta1,alpha7beta1,alpha8beta1,alpha9beta1,alphaXbeta1DDR1 dimer:Collagentype I, II, III,IV, V, XI fibrilsLAMC2 LAMA3 Collagen V Collagen type II fibril LAMA4 ITGA6(24-1130) ITGB1 ITGB1 3x4Hyp-3Hyp-GlcGalHyl-COL9A1 ITGB1 LAMA5 LAMC3 ITGA6(24-1130) LAMC2 LAMC3 5Hyl-COL9A1 3x4Hyp-5Hyl-COL9A3 LamininsFibronectin matrix ITGA2 LAMB1 LAMB2 LamininsBeta amyloid fibrilDSPP(463-1301)LAMB1 ITGA2 LAMA5 LAMC1 3x4Hyp-3Hyp-GlcGalHyl-COL9A3 3x4Hyp-3Hyp-GlcGalHyl-COL9A2 TGFB3 Elastic fibreformationBGN:Collagen typesII, IIIDAG1(30-653)LAMC2 Beta amyloid fibril ITGB6 LAMC1 DAG1(30-653) Collagen type III fibril Collagen type VII fibril TTR COMP pentamer3x4Hyp-3Hyp-GalHyl-COL9A1 LAMA2 DAG1(654-895) CollagentypeIfibril:SPARC:Hydroxylapatitie:Ca2+3x4Hyp-3Hyp-GalHyl-COL9A1 Aggrecan LAMB3 3Hyp-4Hyp-COL9A3 LAMA2 LAMC3 Tenascins C, R, (X,N)LAMB2 3x4Hyp-GalHyl-COL9A2 Integrin alpha5beta1LAMB1 Collagen type VI fibril Collagen type III fibril ITGB1 ASPN LAMC3 PDGFA Integrinalpha6beta1,alpha7beta1,alpha1beta1,alpha2beta1,alphaVbeta1LAMC2 3x4Hyp-COL9A1 DAG1(654-895) LAMA5 FGF2(10-155),Fibronectn matrix,Transthyretintetramer, PDGFAhomodimer, PDGFBhomodimerLAMA1 ITGA3(33-1051) GalHyl-COL9A1 IBSPAGRN(30-2045)Integrin alphaVbeta1LAMA5 DMP1:IntegrinalphVbeta3Tenascin-C hexamerVTN Collagen type I fibril Collagen type II fibril Collagen type XI fibril Collagen type IV alpha1.alpha2.alpha5.alpha6 network LAMA1 Collagen type VIIfibrilLAMA4 MATN4 LAMA4 LAMC2 ITGAV(31-1048) SyndecaninteractionsCollagen types I-V,VIIFibronectin matrix DMP1LAMA5 LAMA3 LAMB1 Collagen type II fibril LAMC2 VTN:IntegrinsalphaVbeta1,alphaVbeta3,alphaVbeta5,alpha2bbeta3AGRN(30-2045) TNC CSE-BGN 3x4Hyp-5Hyl-COL9A1 ITGA3(33-1051) ITGB1 Collagen type XI fibril VTNLAMA3 ITGAV(31-1048) LAMC1 Collagen type III fibril LAMA4 Dystroglycan:AGRN:HSPG2LAMC1 Collagen type VI network Lecticans3x4Hyp-GlcGalHyl-COL9A1 NCAM1, PTPRSITGA6(24-1130) Integrin alpha6beta1LAMA5 LAMC1 DystroglycanLAMA1 COMP Collagen type I fibre TNR Collagen type I fibril Laminins:SulfatideLAMB1 LAMA4 LAMA1 TNXB 3x4Hyp-3Hyp-COL9A2 KS(2),C6S-ACAN LAMB2 GlcGalHyl-COL9A2 Collagen types I,VI, (IX)NRXN1Collagen type II fibril LAMA4 3x4Hyp-GalHyl-COL9A3 Integrinalpha5beta1:FN1dimerLAMA1 Collagen type IV alpha3.alpha4.alpha5 network 3x4Hyp-3Hyp-GalHyl-COL9A2 LRP4:MUSKITGB3 Laminin-111:Endostatin dimerLAMC3 PTPRS Endostatin dimerCollagen type IV alpha1.alpha1.alpha2 network LAMB2 LAMA3 LAMA1 LAMB3 LAMB3 ITGB3 LAMA4 LAMB1 SERPINE1 LAMC1 SH3PXD2A Laminin-111ITGB1 MATN1 LAMA3 LAMA3 ITGA2 VTN:Collagen typesII,III,VCollagen IVLAMA5 LAMA5 AGRN:Laminins withgamma-1LAMA1 ITGB1 LAMA2 ITGA2B(32-1039) Fibronectin matrix COL9A1 Dystroglycan:NRXN13x4Hyp-GlcGalHyl-COL9A1 Collagen type IV alpha1.alpha1.alpha2 network Collagen type VI fibril GalHyl-COL9A3 VTN MATN3 LAMB2 LAMB2 COL9A3 HAPLN1BGN 3Hyp-4Hyp-COL9A3 AGRN(30-2045) Laminins withalpha-1, -2 or-5:HSPG2(22-4391)Integrinalpha7beta1:Laminin-211, 221, 411, 512, 521Collagen type I fibril LAMC1 Vitronectin:Plasminogen activator inhibitor 1Collagen type II fibril Collagen type VI fibril LAMA1 LAMC1 Collagen IV TGFB2 LAMA3 LAMA3 ITGB4 3x4Hyp-COL9A3 ITGA5(42-894) AGRN:Alpha-dystroglycan3x4Hyp-5Hyl-COL9A2 SLRPs:TGF beta3x4Hyp-GlcGalHyl-COL9A2 LAMA3 3x4Hyp-COL9A2 LAMA1 ITGB1 CEACAM heterodimerLUM 3x4Hyp-3Hyp-GlcGalHyl-COL9A1 Ca2+ Dystroglycan:Dystrophin:LamininsLAMA3 Hydroxylapatite 3x4Hyp-COL9A1 LAMB1 Brevican TNC Collagen V Collagen V Collagen type III fibril CSE-BGN COMP interactorsCollagen type I, II,III, IV, V, XIfibrilsLAMB3 Integrinalpha3beta1,alpha6beta4:Laminins-332, 511, 521, (211, 221)DAG1(654-895) Integrin alphaVbeta3ITGAV(31-1048) TGFB1 Collagen type VIIfibril:Laminin-332LAMA2 Integrin alpha7beta1LAMC1 AGRN:LRP4:MUSKLAMA5 CEACAM8 ITGB1 ITGB6 Collagen type X fibril Collagen type II fibril FN1(32-2386) MATN1 LAMC1 Aggrecan Collagen IV LAMB2 LAMA3 Collagen type II fibril Laminins-332, 511,521, (211, 221)Collagen type I fibril Lamininswithgamma-1,gamma-3:Nidogens:Collagen type IV networkLAMC1 Collagen type IfibrilCollagen type I fibril 3x4Hyp-5Hyl-COL9A2 LAMC1 LAMB1 Tenascins C, R, (X,N):FibronectinmatrixNID2 Integrinalpha6beta1,alpha7beta1,alpha1beta1,alpha2beta1,alphaVbeta1:Laminin-111Collagen type III fibril VTN:Collagen typeI,IV,VIIntegrinalpha3beta1,alpha6beta4LAMB3 BGN:Collagen typesI, VI, (IX)PDGFB (82-190) 5Hyl-COL9A3 Collagen type II fibril HSPG2:DystroglycanLAMB2 ITGB4 Collagen type III fibril MATN4 Collagen type IV alpha1.alpha2.alpha5.alpha6 network LAMA2 LAMC2 TNR LAMB1 Laminins withgamma-1Neurocan LAMB1 Collagen type II fibril LAMA3 TGFB3 LAMA1 CSE-BGN LAMC2 LAMA1 TNC:IntegrinalphaVbeta3,alphaVbeta6,alpha2beta1,alpha7beta1,alpha8beta1,alpha9beta1,alphaXbeta1GalHyl-COL9A1 NID1 SERPINE1Collagen type I fibril LAMB2 LAMC1 AGRN(30-2045) Neurocan C4S-BGN Mn2+ CEACAM6 Collagen type I fibril LAMA1 COMP pentamer:COMPinteractorsLAMA3 Laminins withalpha-1, -2 or -53x4Hyp-5Hyl-COL9A3 ITGB1 COL9A1 HSPG2(22-4391) LAMA1 LAMB3 DCN 3x4Hyp-3Hyp-COL9A2 LAMA1 CEACAM1 MUSK ITGB1 AGRN(30-2045) PI(3,4)P2 LAMB3 LAMB2 DDR2 dimer:Collagentype I, II, III, V,X fibrilsDAG1(30-653) LAMA2 DAG1(30-653) 3x4Hyp-COL9A2 LAMA2 Collagen type IV alpha1.alpha2.alpha5.alpha6 network ADAM19 LAMA2 LAMA2 LAMB1 ITGA6(24-1130) LAMA5 LAMC1 ITGB3 3x4Hyp-3Hyp-5Hyl-COL9A2 Collagen type IVnetworks:Collagentype VII fibrilITGB1 ITGA9 3x4Hyp-GlcGalHyl-COL9A2 LAMA5 FN1 dimerLAMA3 Collagen types II,III, VTNXB Collagen type III fibril ITGA9 LAMB1 LAMA1 LAMC1 Nidogens 1, 2Ca2+LAMB3 DAG1(30-653) Brevican LAMA4 FGF2(10-155) Collagen V LAMB1 HSPG2(22-4391) DMDFGF2(10-155) LAMB2 Collagen type II fibril Collagen type II fibril LAMC1 LAMB1 NID2 NID1 Aggrecan:HA:HAPLN1ITGAV(31-1048) TNR LUM Collagen type III fibril DMP1 ITGB1 TNC 3x4Hyp-3Hyp-GalHyl-COL9A3 TNXB C4S-BGN NCAM1 PTPRS LAMA4 MUSK 3x4Hyp-3Hyp-GalHyl-COL9A2 Collagen type I fibril ITGA2 DAG1(30-653) DDR2 LAMA4 LAMC2 LAMB2 DDR1 ITGAX Laminin-111LAMC1 LAMA3 BGNADAM15 3x4Hyp-3Hyp-5Hyl-COL9A3 LAMB1 DSPP(463-1301):Integrin alphaVbeta1ITGAV(31-1048) DDR2 FN1(32-2386) LAMC3 ITGA2 ITGB3 LAMA4 LAMC1 Aggrecan PDGFA LAMB2 ITGB5 ITGA7(34-1181) 3x4Hyp-3Hyp-GlcGalHyl-COL9A3 5Hyl-COL9A1 Versican AGRN(30-2045) COL9A2 Lamininswithgamma-1,gamma-3:Nidogens:HSPG2HAPLN1 ITGB1 LAMB3 LAMB1 ITGA7(34-1181) LAMB1 TGFB2 TNC Collagen type II fibril LRP4 ITGA1 HSPG2(22-4391) NID2 3x4Hyp-GalHyl-COL9A3 ITGAV(31-1048) LAMA4 ITGA7(34-1181) COL18A1(1572-11754) AGRN:Beta amyloidfibrilLaminins withgamma-1,gamma-3:Nidogens1,2LAMA4 PI(3,4)P2 ADAM12 LAMC2 HSPG2(22-4391)Collagen type IV alpha1.alpha1.alpha2 network DDR1 dimerVersican TNN LAMA5 GalHyl-COL9A2 LAMC2 Fibronectin matrix LAMB1 3x4Hyp-GalHyl-COL9A2 Integrinalpha2beta1:Laminin-332LAMB2 Tenascins C, R, (X,N):LecticansLAMB3 3x4Hyp-GlcGalHyl-COL9A3 LAMA5 LAMA3 ITGAV(31-1048) NID1 LAMB3 Laminins withgamma-1, gamma-3HSPG2:FGF2(10-155),Fibronectn matrix,Transthyretintetramer, PDGFAhomodimer, PDGFBhomodimerIBSP:Collagen type IfibrilITGA8(39-1063) DCN 3x4Hyp-COL9A3 3x4Hyp-3Hyp-COL9A1 C4S-BGN Collagen V LAMC3 LAMA5 3x4Hyp-3Hyp-5Hyl-COL9A1 LAMA5 Collagen type VII fibril PDGFB (82-190) ITGAV(31-1048) LAMA1 LAMA3 3x4Hyp-5Hyl-COL9A1 ASPN TNC GlcGalHyl-COL9A3 Collagen type III fibril ITGB5 5Hyl-COL9A2 LAMA2 ITGA6(24-1130) 5Hyl-COL9A2 LAMB2 ITGA7(34-1181) ITGA7(34-1181) KS(2),CSE-ACAN LAMC3 AGRN:NCAM1, PTPRS3x4Hyp-3Hyp-GlcGalHyl-COL9A2 Collagen type I fibril LAMA1 SH3PXD2A:PI(3,4)P2:ADAM12,ADAM15,ADAM19LAMA2 COL9A3 ITGA8(39-1063) Laminin-211, 221,411, 512, 521ITGAX KS(2)-FMOD LRP4 ITGAV(31-1048) Laminin-332DCN Collagen type I fibril LAMA3 Collagen IV ITGB3 C6S-BGN LAMC3 C6S-BGN LAMA5 Collagen type III fibril Collagen type I fibre LAMC2 LAMA2 NID2 3x4Hyp-GalHyl-COL9A1 Collagen type VII fibril Collagen IV Collagen types II,IIIHSPG2(22-4391) Collagen type VI network Collagen type IVnetwork:Laminin-1TNN NTN4:Laminins withgamma-1, gamma-3LAMA2 Aggrecan Collagen type I fibril LAMA5 KS(2),C4S-ACAN ITGA7(34-1181) 5151401634, 57, 736, 23, 33, 61, 757, 22691