HIV Life Cycle (Homo sapiens)

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130, 1511240, 551, 67, 87, 99351572, 84, 94, 13222, 38, 76, 89, 97...1111601254, 56171171959, 51, 11312878, 18, 32, 34, 42...12, 20129121271131295, 167121210, 15, 15216922, 77, 108, 17092, 13393, 136, 1611694029, 98, 112, 13495741282, 169262112601011519, 43, 138, 1663672, 1696415, 69160121, 172113, 16849, 53, 86, 114, 128...6, 24, 47105124, 12348, 66, 11343, 71, 165, 1661226, 11985, 98, 1127, 33, 59, 90, 91, 104...122122103, 1292, 135040, 55, 58, 109, 151...9540, 551216911361, 1531545240, 55, 58, 109, 151...5, 22, 23, 27, 63...79, 80, 16295, 15082, 16945, 76, 88, 116, 143...48, 113, 15725, 102, 1641264116030, 82, 16916043, 16640, 5530, 82, 1691315, 117641104013517126, 1191272, 115, 141, 169113161133, 65, 158741133, 48, 65, 137, 157Golgi membranecytosolendoplasmic reticulum membranenucleoplasmearly endosome membranePOLR2H REV (P04618) protein CCNT1 TAF4 POLR2L p-S2,S5-POLR2A POLR2A TCEB3CL SUPT16H ERCC2 minus sssDNA p6 (P04585) protein GTF2A1(275-376) POLR2F POLR2H GTF2H1 CCNH CCNT1 p51 (RT) CDK7 MA (P04591) protein ERCC2 UBB(77-152) NC (P04585) protein p-S2,S5-POLR2A REV (P04618) protein POLR2A VPR (P69726) protein p6 (P04591) protein VPR VIF (P69723) protein RTC with minusstrand DNAsynthesis initiatedfrom 3'-endGTF2H1 POLR2F p-SUPT5H POLR2L p51 (RT) IN (Integrase) (P04585) protein GDP TCEB2 REV (P04618) protein MNAT1 UBC(305-380) TAF5 GTF2F1 Transmembrane protein gp41 CDK9 POLR2J GTF2B TCEB3 NELFCD TAF3 POLR2D XRCC5:XRCC6POLR2K GTF2H3 GTF2F1 CCNH p-S5-POLR2A POLR2A POLR2B POLR2K tRNA-Lysine3 POLR2H POLR2F NELFE POLR2C POLR2B POLR2B TFIIDTAF13 POLR2G TCEB3C NC (P04585) protein TCEB3 REV (P04618) protein POLR2C TAF11 POLR2A Reverse transcriptase/ribonuclease H p-S5-POLR2A tRNA-Lysine3 REV (P04618) protein POLR2L MA (P04591) protein GTF2H2 HIV-1 template DNA:30 nt transcript hybrid GTP POLR2I POLR2D P-TEFb(CyclinT1:Cdk9)-containingelongation complexwith separated anduncleavedtranscriptGTF2H2 POLR2H HMGA1 TAF13 viral minus strand DNA with sticky 3' end CDK9 GTF2H4 NELFA POLR2H NELFB POLR2L ERCC3 SEC13 TCEB2 CHMP6 CTDP1 Host genomic DNA tRNA-Lysine3 GTF2F1 POLR2B ATP p-SUPT5H p-SUPT5H TAF9 ERCC3 VPS37C NUP98-5 GTF2F1 CCNT1 POLR2D TCEB3CL TCEB3B POLR2B ATP p6 (P04585) protein NELFCD SUPT16H MA (P04591) protein RAE1 RTC with duplex DNAcontainingdiscontinuous plusstrand flapPOLR2C TAF11 SUPT4H1 NELFB NELFB TAF5 RTC with degradedRNA template andminus sssDNAPOLR2H POLR2G NUP88 GTF2E1 GTF2F2 P-TEFb(CyclinT1:Cdk9) complexTCEB1 POLR2E POLR2B GTF2H2 POLR2J capped HIV-1 pre-mRNA ERCC2 NC (P04591) protein XPO1 p6 (P04591) protein UBB(153-228) Reverse transcriptase/ribonuclease H PPIA CCR5 HIV-1 transcriptioncomplex containing3 nucleotide longtranscriptIN (Integrase) (P04585) protein tRNA-Lysine3 SUPT16H CHMP4C NUPL2 POLR2B POLR2G POLR2F TCEB2 GTF2H4 NUP188 POLR2C NELFB UBB(153-228) CCNH NUP93 VPU (P05919) protein VPR GTF2H2 TCEB3C GTF2H4 POLR2H NUP62 UBC(153-228) TCEB3CL TAF7 viral minus strand DNA (full-length) POLR2D GTP UBC(533-608) TFIIDp6 (P04591) protein NTPPol II transcriptioncomplex containingextruded transcriptto +30ATP POLR2H POLR2D POLR2F p6 (P04591) protein NELFA RAN Multimeric capsid coat VPR (P69726) protein TAF5 UBC(609-684) minus sssDNA TCEB3C POLR2K CCNT1 GTF2H5 HIV-1 RNA POLR2L CCNH SUPT4H1 p-S2,S5-POLR2A dNTPtRNA-Lysine3 GTF2A1(275-376) viral plus strand DNA (full-length) SUPT4H1 CCNH TCEA1 Elongating HIV-1 transcript in processive Pol II mediated elongation p51 (RT) POLR2K POLR2E POLR2E CCNT1 TAF9 NUP93 POLR2H VPS37D IN (Integrase) (P04585) protein ERCC2 HIV-1 RNA template TCEB1 Multimeric capsid coat TAF12 POLR2J GTP GTF2F2 TAF5 viral plus strand DNA (full-length) Reverse transcriptase/ribonuclease H SSRP1 IN (Integrase) (P04585) protein UBA52(1-76) POLR2D UBC(457-532) Integrated provirusminus sssDNA BANF1 TAF1L NUP35 p6 (P04591) protein TCEB1 POLR2E Reverse transcriptase/ribonuclease H CCNT2 VPS28 POLR2K PR (Protease) (P04585) protein MNAT1 TAF5