Mitotic Prometaphase (Homo sapiens)

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12, 20, 23, 29, 32...10, 19, 423, 11, 27, 3737, 14, 39, 401410, 13, 17-19, 21...201, 20, 28, 35, 3619, 4519, 4515, 443, 9, 11, 22, 24...231333, 3039, 4010, 23, 424-6cytosolDYNC1LI1 CENPI CETN2 PPP2R5B CENPN MAPRE1 NUP160 MAPRE1 CENPH RANBP2 SGOL1 TUBB4B NUP133 DYNC1LI2 NUP43 SPC24 ALMS1 KIF2A SMC1A CENPA CEP72 Microtubule protofilament KIF2C PCM1 PPP2R5B MAD1L1 BIRC5 PRKAR2B SEH1L-1 MLF1IP PLK4 CENPT CEP57 CENPE MZT1 PLK1 NEDD1 CKAP5 CENPE MAD2L1 2xAcK-SMC3 SPC25 MAD2L1 SKA2 NUP133 PPP2CA DCTN1-2 CENPE STAG2 KIF18A CENPF CENPJ DYNLL1 SKA2 HAUS6 RANGAP1 WAPAL CASC5 Ac-CoA2xAcK-SMC3 HAUS4 ATPKIF18A p-S454-RAD21 STAG1 KIF2B CENPN SFI1 CKAP5 BUB3 p-T-NCAPH PMF1 p-S454-RAD21 CENPJ NUF2 p-S454-RAD21 SKA2 CENPE ITGB3BP APITD1 CENPC1 PPP2R5D ZWINT PPP2R1A PPP2R1B CENPQ MAPRE1 NUDC ACTR1A BUB1 OFD1 CSNK2A2 BUB1 EML4DYNC1I2 WAPAL CDCA8 PPP2R1B SEC13 CENPQ PiCENPL CENPQ DYNLL2 BUB3 DSN1 CEP192 WAPAL ADPPPP2R5A 2xAcK-SMC3 MAD2L1 AURKB SGOL2 ZW10 RCC2 SMC1A CNTRL BUB3 CENPQ MIS12 DSN1 NDE1 SMC1A NDEL1 RAD21 PAFAH1B1 NUDC NCAPD2 TUBB4B PPP2R1B DCTN2 NSL1 CLASP2 p-T161-CDK1 PCNT STAG1 PPP2R5D INCENP AKAP9 CENPP CDCA8 Condensed prophasechromosomesNUP98-5 CENPA p-S21,S75,T159-CDCA5 ZWINT PPP2R5B NEK2 ATPKIF2B DYNC1LI1 CLIP1 CEP57 MAPRE1 KNTC1 CKAP5 AHCTF1 NDE1 PPP2CA FGFR1OP HAUS5 NUDC APITD1 BUB1B PDS5A CASC5 CDCA8 MIS12 HAUS4 CEP76 RANGAP1 CLIP1 NCAPH SSNA1 CENPI p-S195-NEK7 p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:MicrotubulesPPP2CB ITGB3BP CDK1 WAPAL SPC25 2xAcK-SMC3 NEK2 HAUS7 NDE1 DYNLL1 ADPRANBP2 p-STAG2 KIF2A Sister Centromere RANGAP1 SPDL1 PLK1BUB1 SMC1A CENPQ RANGAP1 CENPN NUDC CEP41 PPP2CA DYNC1LI2 p-STAG2 PPP2CA NME7 WAPAL RANBP2 CDC20 NDC80 CEP78 KNTC1 OFD1 CENPP PRKACA SDCCAG8 DYNC1H1 SPC24 CCP110 PPP2R1B ERCC6L PLK1 Unknown PhosphatasePRKACA KIF18A DYNC1I1 CENPI TUBB4A p-NUMA1 STAG1 Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:MicrotubulesZWILCH SEC13 PPP2R5C Maturecentrosomeenrichedingamma-TURC:p-T2055-NUMA1 homodimerAURKB MLF1IP PCNT Microtubule protofilament KNTC1 MAPRE1 MAPRE1 PMF1 PPP2CA TAOK1 CENPA HAUS2 p-S21,S75,T159-CDCA5 NUP133 DYNC1I2 DYNLL2 CLASP1 AURKB NUF2 DYNC1I1 CDC20 CASC5 CENPM MZT2B NUP133 Sister ChromosomalArmDYNLL1 CEP78 CLASP1 CEP164 KIF18A MAD1L1 BUB3 PPP2R1A NUP85 p-S29,T210,T333,S750,S869-NEK9 MLF1IP SMC1A CENPC1 TUBGCP4 NUP160 NUDCHAUS2 HSP90AA1 PPP2CA AHCTF1 p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochoreCLIP1 PPP1CC APITD1 DYNC1H1 MIS12 NINL KIF2B B9D2 PPP2R5C CENPA NDE1 ATPHAUS3 TAOK1 HAUS4 NUF2 PCM1 CSNK1E CLASP2 BIRC5 NUP37 RPS27 PPP2R1A SPC24 DSN1 KIF2C PPP2R5E SKA1 SGOL1 PLK1 PPP1CC NUP107 p-S,T-EML4 NUP37 STAG1 TUBB4A NSL1 CEP76 STAG2 DYNC1H1 SGOL1 CENPH PLK1 CEP63 CENPH BUB1 KIF2C PPP2R5E SisterCentromeres:Ac-Cohesin:PDS5:CDCA5:WAPALBIRC5 STAG1 Sister Chromosomal Arm ERCC6L p-S21,S75,T159-CDCA5MZT2A SEC13 NUP107 NUF2 ALMS1 NUP107 MLF1IP CDCA8 RAD21 DYNLL1 CASC5 AURKB YWHAG p-T2055-NUMA1homodimer:Maturecentrosome:nucleated microtubulesZW10 CKAP5 CSNK2A1 Microtubule protofilament SDCCAG8 CDCA8 Microtubule protofilament MIS12 PDS5A MZT2A Microtubule protofilament HAUS7 NUP85 SMC2 AHCTF1 DYNC1H1 2xAcK-SMC3 CASC5 PAFAH1B1 CEP250 CEP70 PMF1 RCC2 FGFR1OP ZW10 SMC3 CLASP1 CENPC1 SPC24 PPP1CC CEP41 NUP107 MAD2L1 CDCA5 PPP2R5A HAUS3 MAD1L1 ZWINT CDCA8 SGOL1 NDC80 KIF18A B9D2 ATPPLK1 INCENP TUBGCP3 ATPDYNLL1 DYNLL2 CKAP5 DYNC1I2 PPP2R5D ACTR1A TUBGCP2 PAFAH1B1 HDAC8-1 NUP133 AHCTF1 Casein kinase IISMC4 CEP76 NSL1 CETN2 PLK1 HAUS1 CKAP5 TUBGCP5 NUDC SEH1L-1 AHCTF1 SFI1 RPS27 CLASP2 EML4 NDE1 p-Cohesin:PDS5:WAPALPPP2CB DYNC1I1 NDEL1 CENPC1 CLASP1 MAD1L1 Sister Chromosomal Arm RAD21 PPP2CB PPP2R1B SEH1L-1 TUBA4A Microtubule protofilament BIRC5 PPP2R5C KIF2B MicrotubuleNDEL1 CETN2 NUP98-5 SKA2 CENPF Mature centrosomesenriched ingamma-TURCcomplexesHAUS8 CENPP p-S454-RAD21 CENPT SFI1 CENPN CENPH RANGAP1 CLIP1 DYNC1LI1 SEC13 PMF1 SGOL1 XPO1 YWHAE PRKAR2B SPDL1 CENPF MAD2L1 RPS27 CENPE OFD1 MAD2L1 MZT2A TUBG2 NSL1 NUP160 p-3S,2T-NEK9:p-S206-NEK6/p-S195-NEK7p-STAG2 S PhaseZWINT CLIP1 p-S21,S75,T159-CDCA5 CSNK1D MAPRE1 AURKB NDEL1 PAFAH1B1 RCC2 SKA2 NDEL1 CENPC1 CKAP5 p-S274,S326-NUDC CDK1 p-NUMA1 STAG2 DSN1 NEDD1 WAPAL PMF1 RANBP2 PDS5B p-S21,S75,T159-CDCA5 TUBB4A BIRC5 ADPBUB3 DYNC1LI1 SGOL1 PDS5B AURKB SMC1A ZW10 MIS12 NME7 CEP290 RCC2 B9D2 BUB1B PPP2R5A SMC1A DCTN3 ALMS1 SGOL2 NUP43 TUBGCP3 MAD2L1 2xAcK-SMC3 ZWILCH KIF18A CENPO p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:MicrotubulesHAUS5 RPS27 TUBB PPP2R1A NDE1 SKA1 NUF2 SGOL2 DYNLL2 p-S274,S326-NUDCSSNA1 CENPJ DYNC1LI2 MLF1IP CLIP1 KIF2A Microtubule protofilament ITGB3BP NUP98-5 NDC80 SSNA1 PPP2R1A ODF2 ERCC6L CEP152 ODF2 CENPL NUP37 CENPA CCNB2 HAUS1 PDS5B NSL1 DYNC1I2 NDEL1 PDS5A PPP2R1A PCM1 RANBP2 ERCC6L HAUS7 MZT2B NUP85 CENPL PPP2R5E TUBA4A p-T308,T332-NCAPG RCC2 TAOK1 ACTR1A 2xAcK-SMC3 BUB3 RANGAP1 Sister Centromere CEP78 CCP110 PAFAH1B1 PPP1CC NSL1 KIF2C SPDL1 WAPAL CEP72 PPP2CA KIF2A CASC5 MAD1L1 CEP152 TUBA1A CENPN PDS5B CENPM DCTN2 NUP160 CLIP1 CDC20 WAPAL TAOK1 PPP2R5D YWHAE CCNB1 DSN1 PPP2R1A ITGB3BP ERCC6L YWHAG DYNC1I2 SEC13 NDC80 NEK2 ZWILCH KIF2B CCP110 ITGB3BP STAG2 BUB1B PPP2R5E SPC25 RANBP2 KIF2C Condensin ISKA2 SMC2 PPP2R1B ITGB3BP PDS5A CENPA NUP85 ITGB3BP STAG2 CENPN NDE1 AZI1 DSN1 ZWILCH CENPM AHCTF1 SisterChromosomalArms:p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPALBUB1 SGOL2 HSP90AA1 DYNLL2 CENPP HDAC8CLASP2 WAPAL NUP85 Microtubule-boundkinetochoreCENPM MLF1IP SGOL2 CENPK PPP2R1A CENPC1 CENPO MZT2B PPP2R5D PPP2R5D CDCA5 ATPTUBGCP6 APITD1 ERCC6L CSNK2B MZT1 CENPQ CNTRL PDS5A NCAPG CENPH CDK5RAP2 CEP164 SGOL2 DYNC1LI2 CENPI Sister Centromere HAUS8 SEH1L-1 KIF2B CEP41 ATPFGFR1OP NUP37 SPDL1 PAFAH1B1 KNTC1 DYNC1H1 APITD1 BUB1B HAUS1 DYNC1I1 PRKACA HAUS3 SMC1A CENPK NUP37 RPS27 DYNC1LI1 NUP160 NUF2 PRKAR2B HAUS5 CDCA5 p-S-SMC4 SPDL1 XPO1 DYNC1LI2 KIF2C NUDC CEP135 AKAP9 PAFAH1B1 ADPCDK1 PhosphorylatedCondensin ININL PMF1 NUP107 Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:MicrotubulesPPP2CB DYNC1I2 p-S-NCAPD2 CENPM CondensedprometaphasechromosomesCDC20 TAOK1 TUBG1 PDS5B 2xAcK-SMC3 ZW10 STAG1 p-Ac-Cohesin:PDS5:WAPALINCENP PPP1CC CENPF B9D2 TUBGCP5 NSL1 DCTN1-2 B9D2 BUB1B NUP37 CEP135 CLASP1 SMC2 TAOK1 ATPPPP2R5A XPO1 DYNC1H1 STAG2 PAFAH1B1 RANGAP1 DYNC1H1 PDS5B DSN1 PDS5B DYNC1H1 CDC20 PDS5B SEC13 2xAcK-SMC3 TUBGCP6 CEP135 ZWINT XPO1 DYNLL1 CEP70 EML4 SKA1 CSNK1E PDS5B p-S570-NCAPH PAFAH1B1 DYNC1I2 CENPL NUP160 ZWINT KIF2C CENPK NUP107 PiCENPN PDS5A PLK1 NUP43 CENPT DYNLL1 CKAP5 NUP98-5 SPC25 MZT1 TUBG2 CEP250 TUBA1A TUBG1 CENPF MAD1L1 CENPI SisterChromosomalArms:Ac-Cohesin:PDS5:p-CDCA5:WAPALBIRC5 SEH1L-1 NUP133 CENPK p-S21,S75,T159-CDCA5 TUBGCP5 SKA1 PPP2CB PPP2R5C PPP2R1A RCC2 CLASP1 CENPI DCTN2 SPC25 STAG1 SPDL1 SGOL1 CENPQ NUP37 INCENP CENPF p-T2055-NUMA1homodimerSPC24 TUBB4B ZWILCH STAG1 AURKB DYNC1I1 PLK1 CK2 PhosphorylatedCondensin IRPS27 EML4 CENPH Microtubule protofilament CENPF CEP290 STAG1 CENPL AHCTF1 CEP192 CENPT CEP250 CENPP SPC24 MIS12 CENPM SEH1L-1 CENPI CDK1 PCNT TUBG2 CENPM ADPSister Centromere CNTRL CSNK1D PDS5A PPP2R5E p-STAG2 MAPRE1 CLASP1 CENPO NUF2 CENPK SKA2 MAPRE1 NDE1 ADPRPS27 NUP43 PPP2R5C ZWILCH PLK1 CLASP1 TUBGCP2 NUP98-5 CENPA STAG1 PLK1 DCTN3 RCC2 DYNC1LI2 NDE1 PPP2R5E CEP63 MAD1L1 CEP70 PDS5A SGOL2 PPP2R5C HAUS6 PPP2R5B BUB3 PPP2CB CEP72 ADPXPO1 PPP2R5A APITD1 NUP43 Mitotic ProphaseXPO1 KNTC1 CLASP2 CENPT AZI1 KIF18A CEP57 CENPT PAFAH1B1 CLASP2 CENPL DYNC1LI1 SMC1A AKAP9 XPO1 HAUS8 ERCC6L TUBGCP6 KNTC1 PPP2R5B CoA-SHZW10 CENPL SKA1 PMF1 KinetochorePPP2R5B Sister Chromosomal Arm KIF2A DYNC1H1 TUBG1 CENPO TUBA4A DCTN1-2 DCTN3 DYNLL2 NUP85 TUBGCP2 CENPK p-T1339,T1384,T1389-NCAPD2 CENPP CLASP1 p-T210-PLK1INCENP PLK4 PPP2R5C MAPRE1 CCNB1,CCNB2:p-T161-CDK1NDC80 NUP133 DYNLL1 DYNC1I2 Sister Centromere TUBGCP4 PPP2R5B CDK5RAP2 DYNC1LI2 CENPP PPP2CB NEDD1 SMC1A DYNC1I2 CENPO ZWINT CENPE NUP43 KIF2A NDC80 p-S206-NEK6 TUBGCP3 ODF2 AZI1 TUBGCP4 SKA1 SMC4 WAPAL HAUS2 TUBA1A DYNLL2 PPP2R1B BUB1B CENPH SEH1L-1 YWHAE B9D2 SDCCAG8 CEP192 CEP63 ADPCDC20 PPP2R5E CENPK CEP152 p-S454-RAD21 CEP164 PPP2R5A RAD21 TUBB CDCA8 ZW10 TAOK1 SKA1 NUP85 RAD21 KNTC1 PPP1CC NDEL1 PPP2R1A BUB1B APITD1 CENPC1 CLASP2 DYNLL1 NDE1 p-S-NCAPG PDS5A YWHAG NDC80 DYNC1I1 PDS5A SPC25 BUB1 EML4 homotrimerp-S,T-EML4homotrimerH2OZWILCH CSNK1D H2OBUB1 CENPE BIRC5 DYNC1I2 DYNC1LI1 CENPO HSP90AA1 NUP107 SEC13 CDC20 NME7 CKAP5 INCENP PDS5B Microtubule protofilament CKAP5 TUBB CSNK1E NINL PLK4 NUP98-5 EML4homotrimer:MicrotubuleCEP290 NUP160 INCENP CLASP1 SPC24 p-NUMA1 DYNC1H1 CASC5 MLF1IP SisterChromosomalArms:Ac-Cohesin:PDS5:CDCA5:WAPALPPP2R5A DYNLL1 KIF2B NUDC NUP98-5 KIF2A CENPO RANBP2 HAUS6 SPC25 NUP43 CDK5RAP2 B9D2 DYNC1I1 CENPT Mitotic Metaphaseand AnaphaseMIS12 PPP1CC PPP2R5D SPDL1 8, 1614, 401111