TGF-beta Receptor Signaling Pathway (Mus musculus)

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CYEndosomeCYNUCYLigandCYPlasma membraneEndoplasmic reticulumCYExtracellularDeubiquitinationNUCYMolecule in the pathwayCYNUCYCYNUNUGlycosylationCYCYECCYNucleusMethylationNUNUTranslocationCYMitochondriaDemethylationNUNU -> CYNUCYEnzyme complexCYSumoylationMolecular associationNUENCYCYProteins in a complex interactionCYGlycosylationCYReaction through unknown mechanisms/moleculesGONU -> CYPalmitoylationDNUCY(Protein-protein interaction)AutophosphorylationDephosphorylationNUInhibitionCYAcetylationActivationCYNUCYCYUbiquitinationNUNUNUNUNUGolgi apparatusReceptorPhosphorylationNUNUMTProteolytic cleavagePMERCYNUNUDesumoylationCYRecruitmentNUCYDeacetylationNUNUNUAccession Number: NetPath 7; cellmap: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 SymbolSnx6Snip1Smad3Cav1Tgfbr3Tgfb2Dab2Smad3Atf2Axin1Hoxa9Stambpl1StrapSmad3Tgfbr2SparcFosRbl2Mef2cAnapc7Cdc27Ube2d2Foxh1Tgfbr2Rb1Tfdp1Cul1Tgfbr1Ets1Camk2aAcvrl1Cul1Tfdp2


Description

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Comments

GenMAPP notes 
NetPath 7; cellmap:7 - TGF-beta Receptor Signaling Pathway

The TGF-beta Receptor Signaling pathway was kindly reviewed by Van Le Hong, Wei He and other members of Joan Massague’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.

GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org

Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
111024view14:42, 30 June 2020L DupuisConverted interactions in legend to graphical lines
73847view00:33, 26 February 2014MaintBotupdated schema
71764view20:29, 17 October 2013MaintBotremoved data source from nodes without identifier
67695view11:50, 26 June 2013DdiglesOntology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
41259view00:20, 2 March 2011MaintBotRemoved redundant pathway information and comments
34374view22:44, 9 December 2009MaintBotAutomatic update of empty xrefs
28139view21:51, 27 January 2009KhanspersReverted to version '11:31, 14 November 2008' by Khanspers
28138view21:50, 27 January 2009KhanspersChanged name
21221view11:31, 14 November 2008MaintBot[[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:WP258]]: Moved to stable identifier
8436view13:46, 7 January 2008MaintBot[[Pathway:Mouse:TGF-beta-Receptor NetPath 7]] moved to [[Pathway:Mus musculus:TGF-beta-Receptor NetPath 7]]: Renaming species
7834view16:21, 18 December 2007MaintBotfixed category names
7305view12:42, 4 November 2007MaintBotAdded categories to GPML
6501view22:19, 22 May 2007A.PandeyReverted to version '14:05, 9 March 2007' by Thomas

External references

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