Methylcitrate cycle (Mycobacterium tuberculosis)

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12-methylcitrate synthase activitySuccinate2-methylisocitrate lyasemalate dehydrogenase activityMethyl IsocitrateFumaraseOxaloacetate2-methylcitrate dehydratase activityPyruvateAconitasemalate quinone oxidoreductase;Propionyl-CoAMalatesuccinate dehydrogenase activityMethylcitrateFumarate


Description

The Methylcitrate cycle oxidizes Propionyl-CoA to pyruvate.

Quality Tags

Ontology Terms

 

Bibliography

  1. Muñoz-Elías EJ, Upton AM, Cherian J, McKinney JD; ''Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence.''; Mol Microbiol, 2006 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
87827view11:43, 25 July 2016ElisaOntology Term : 'classic metabolic pathway' added !
78230view16:33, 14 December 2014MaintBotAdded a missing data source.
78229view16:32, 14 December 2014MaintBotWidened boxes a bit to make all labels visable.
70838view16:58, 11 September 2013AndraPeriodical save, work in progress
70818view17:06, 9 September 2013AndraModified description
70817view17:03, 9 September 2013Andra
70816view16:59, 9 September 2013AndraSpecify description
70814view16:48, 9 September 2013AndraFinished pathways
70813view16:35, 9 September 2013AndraPeriodical save, work in progress
70812view16:24, 9 September 2013AndraPeriodical save, work in progress
70811view16:14, 9 September 2013AndraNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
2-methylcitrate dehydratase activityGeneProductGO:0047547 (GeneOntology)
2-methylcitrate synthase activityGeneProductGO:0050440 (GeneOntology)
2-methylisocitrate lyaseGeneProduct
AconitaseGeneProduct
FumaraseGeneProduct
FumarateMetabolite4573886 (Chemspider)
MalateMetabolite140981 (Chemspider)
Methyl IsocitrateMetabolite1161 (Chemspider)
MethylcitrateMetabolite500 (Chemspider)
OxaloacetateMetabolite2509917 (Chemspider)
Propionyl-CoAMetabolite83731 (Chemspider)
PyruvateMetabolite96901 (Chemspider)
SuccinateMetabolite140973 (Chemspider)
malate dehydrogenase activityGeneProductGO:0016615 (GeneOntology)
malate quinone oxidoreductase;GeneProduct
succinate dehydrogenase activityGeneProductGO:0000104 (GeneOntology)

Annotated Interactions

No annotated interactions

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