TNF-alpha NF-kB Signaling Pathway (Mus musculus)

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SumoylationProteolytic cleavageCY ->NUEndosomeDesumoylationControlENGolgi apparatusUbiquitinationMitochondrionNucleus(Protein-protein interaction)Endoplasmic reticulumERCY ->NUCY ->NUEnzyme complexAccession Number: NetPath 9; cellmap:9MethylationRecruitmentDReceptorDemethylationGOGlycosylationReaction through unknown mechanisms/moleculesProteins in a complex interactionLigandPMAcetylationCY ->NUCYDeacetylationNUTranslocationMolecular associationCytoplasmPlasma membraneActivationPalmitoylationAutophosphorylationECDephosphorylationInhibitionMolecule in the pathwayDeubiquitinationCY ->NUPhosphorylationMTExtracellularRipk3Kpna6Iqgap2G3bp2BCL7AMcm7Traf1Psmc1Akap8YwhabPsmb5Rps11Map3k2Cdc34RelaRasal2Faf1Smarcc2Psmd6RelbNsmafTnip2RPS6KB1Csnk2bTraf6Pebp1Gm4596Map3k7ip3Ripk2Zfand5Casp8ap2Trpc4apCASP10Psmc2ChukCops3Ptpn11Polr1cMtif2Smarcc1Tnfrsf8Polr1eRelaSmarce1Kpna3ChukTnfrsf11aRipk1Smarca4Tnfrsf1aPsmd3Polr2hBag4DapHsp90aa1Stat1PrkczPsmd13YwhahBirc2Nkiras1Pias3SUMO1Gene SymbolRipk1Tnfrsf1b2610301G19RikMap3k3Cd3eapGlg1TraddRelGab1Bcl3Casp7Cul1BtrcUsp11Akt2IkbkgCapn3UBCH5BFaddEif4a3Nlrp4eCasp8Tnfrsf1bRnf25AlplRelbGnb2l1RelaTnfHdac1Polr1aYwhagKtn1Gm2423Tbk1Rnf216MCCUsp2Wdr68TxlnaPfdn2IkbkapPsmc3Ptk2GeneMap3k14LrpprcFancd2Traf4Birc3Cav1Unc5clNr2c2Map3k1Nfkb1Ddx3xBirc3Tnfrsf1aNfkbiaTnfrsf1bPmlPapolaTnfTnfTraf4Hdac6Psmd12GeneCyldRelaCommd1Traf5IkbkeRps6ka5Nfkb2NfkbiaTraf1Casp3Hdac2Polr1dNfkbieFbxw11Map2k5Map3k3GeneSKP1ANr2c2YwhaeTnip1Actl6aTraddGsk3bHsp90ab1Ppp1r13lBirc2TifaCdc37Mark2Gtf2iGeneFkbp5Traf3NfkbiaPdcd2Polr1bTraf2CSNK2A1Map3k7ip1Map3k7ip2Azi2CrebbpTnfSmarcb1HIST3H3FblTbk1YwhazTraf2Ube2iPkn1TankFlnaAkt1IkbkgDpf2Mcm5Nkiras2TnfPsmd1KPNA2SrcCflarCsnk2a2Casp2Nfkb1Kcnq1NfkbizRPL8TraipRPS13PrkacaRPL6IkbkbTraf2Rpl4Peg3Map3k8Tnfaip3Nfkb1NfkbibCraddRelTnfrsf1aTnfPsmd7RPL30Gm10774Hspb1Ppp2ca