1, 2ES/IPS cellsHypoxiaPOU5F1Retinoic acidINSNANOGSOX2LIN28ALIN28BZFP42THY1EctodermSOX1PAX6EndodermSOX17FOXA2MesodermMesodermProgenitorNCAM1TANPEPMIXL1ROR2WNT3ABMP4INHBAGSK3BFGF2Day 1Day 2CardiacMesodermMESP1MESP2KDRKITDay 3-4CXCR4PDGFRANOTCH1CardiacProgenitorISL1NKX2-5GATA4TBX5Day 5-6TBX20MEF2CMAPK14BMP1NOGNODALTGFB1WNTDKK1ImmatureCardiomyocyteMYH6TNNT2TNNI3MYLK3Day 7SIRPAMEF2CMatureCardiomyocyteTNNT2ACTC1MYL2SCN5ADay 30+IRX4IGF2IGF1WNT3ANRG1