Pilocytic astrocytoma (Homo sapiens)

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In this pathway shows the signaling in the development and behavior of the disease. receptor tyrosine kinase(rtk) is expressed in tumor endothelial cells of adult glioblastomas.NF1 and BRAF genes induced the tumor growth.

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94224view22:42, 25 August 2017DeSlChanged RTK metabolite node to protein node, added ID for this node.
74520view21:34, 28 April 2014KhanspersModified title
69013view17:47, 8 July 2013MaintBotUpdated to 2013 gpml schema
67597view11:31, 26 June 2013DdiglesOntology Term : 'glioma pathway' added !
59199view19:14, 22 February 2013MaintBotUpdated Ensembl and UniProt data source
54370view15:01, 28 November 2012MaintBotremoved mim-gap end type
53138view02:00, 30 October 2012MaintBotModified categories
49791view10:47, 26 July 2012DeviModified description
49790view06:50, 26 July 2012DeviPilocytic astrocytoma
49771view19:24, 25 July 2012MaintBotconnected nodes to database object
49739view10:32, 25 July 2012DeviNew pathway

External references


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NameTypeDatabase referenceComment
GRB2GeneProductENSG00000177885 (Ensembl)
NF1GeneProductENSG00000196712 (Ensembl)
PTPN11GeneProductENSG00000179295 (Ensembl)
RAS:GDPMetaboliteHMDB00960 (HMDB)
RAS:GTPMetaboliteHMDB01440 (HMDB)
RTKProteinEC (Enzyme Nomenclature)
SOS1GeneProductENSG00000115904 (Ensembl)

Annotated Interactions

No annotated interactions

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