Methylerythritol phosphate pathway (Oryza sativa)

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LOC_Os01g01710LOC_Os02g45660EC:2.7.7.60ADPgeranylgeranyldiphosphate biosynthesis II (plastidic)LOC_Os07g09190CO2LOC_Os03g52170EC:4.6.1.121-deoxy-D-xylulose 5-phosphateΔ3-isopentenyl-PPNADPHEC:1.1.1.267pyruvateprotein dithiolNADP+phytyl-PP biosynthesis4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolLOC_Os07g361902-C-methyl-D-erythritol-2,4-cyclodiphosphateLOC_Os02g39160CMPdimethylallyl-PPpolyisoprenoid biosynthesisEC:2.2.1.7diphosphate2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolH2OD-glyceraldehyde-3-phosphateLOC_Os05g34180LOC_Os06g05100EC:1.17.1.21-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphateEC:5.3.3.2EC:2.7.1.148CTP2-C-methyl-D-erythritol-4-phosphateLOC_Os01g66360ATPLOC_Os07g40260EC:1.17.4.3LOC_Os05g33840LOC_Os01g58790protein disulfideNAD(P)+NAD(P)HH2OH+


Description

In plants, the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway located in the plastids provides precursors for the isoprenoid hormones, monoterpenes, carotenoids and chlorophyll side chains, prenylquinones and tocopherol biosynthesis.

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
98196view10:19, 5 August 2018EgonwReplaced the CAS number of a salt with that of the parent compound.
94568view06:49, 28 September 2017DeSlAnnotated metabolite node; changed 2 metabolite nodes to proteins, changed ID for NAD(P)H to correct one.
89689view10:07, 26 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
86878view07:46, 14 July 2016MkutmonOntology Term : 'tetrahydrobiopterin metabolic pathway' added !
86877view07:46, 14 July 2016MkutmonOntology Term : 'PW:0000217' removed !
71857view20:33, 18 October 2013EgonwFixed the KEGG Compound database name.
70139view20:57, 12 July 2013MaintBotupdated to 2013 schema
57085view20:43, 20 January 2013EgonwAdded missing CAS data source.
48985view22:51, 2 July 2012PjaiswalModified categories
48635view22:06, 7 June 2012PjaiswalModified description
48634view22:02, 7 June 2012PjaiswalOntology Term : 'plant cell' added !
48633view22:02, 7 June 2012PjaiswalOntology Term : 'metabolic pathway of prosthetic groups, electron carriers and reductants' added !
48632view22:00, 7 June 2012Pjaiswaladded xref to EC:1.17.4.3
48630view21:42, 7 June 2012PjaiswalNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1-deoxy-D-xylulose 5-phosphateMetaboliteC11437 (KEGG Compound)
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphateMetaboliteC11811 (KEGG Compound)
2-C-methyl-D-erythritol-2,4-cyclodiphosphateMetaboliteC11453 (KEGG Compound)
2-C-methyl-D-erythritol-4-phosphateMetaboliteC11434 (KEGG Compound)
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolMetaboliteCHEBI:16840 (ChEBI)
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritolMetaboliteC11435 (KEGG Compound)
ADPMetabolite58-64-0 (CAS)
ATPMetabolite56-65-5 (CAS)
CMPMetabolite63-37-6 (CAS)
CO2Metabolite124-38-9 (CAS)
CTPMetabolite65-47-4 (CAS)
D-glyceraldehyde-3-phosphateMetabolite591-57-1 (CAS)
EC:1.1.1.267GeneProduct1.1.1.267 (Enzyme Nomenclature)
EC:1.17.1.2GeneProduct1.17.1.2 (Enzyme Nomenclature)
EC:1.17.4.3GeneProduct1.17.4.3 (Enzyme Nomenclature)
EC:2.2.1.7GeneProduct2.2.1.7 (Enzyme Nomenclature)
EC:2.7.1.148GeneProduct2.7.1.148 (Enzyme Nomenclature)
EC:2.7.7.60GeneProduct2.7.7.60 (Enzyme Nomenclature)
EC:4.6.1.12GeneProduct4.6.1.12 (Enzyme Nomenclature)
EC:5.3.3.2GeneProduct5.3.3.2 (Enzyme Nomenclature)
H+Metabolite12408-02-5 (CAS)
H2OMetabolite7732-18-5 (CAS)
LOC_Os01g01710GeneProductLOC_Os01g01710 (Gramene Rice) 1-deoxy-D-xylulose 5-phosphate reductoisomerase, chloroplast precursor, putative, expressed//isoprenoid biosynthetic process//catalytic activity//1-deoxy-D-xylulose-5-phosphate reductoisomerase
LOC_Os01g58790GeneProductLOC_Os01g58790 (Gramene Rice) GHMP kinases ATP-binding protein, putative, expressed//ATP binding//terpenoid biosynthetic process//4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase
LOC_Os01g66360GeneProductLOC_Os01g66360 (Gramene Rice) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putative, expressed//terpenoid biosynthetic process//4-diphosphocytidyl-2C-methyl-D-erythritol synthase
LOC_Os02g39160GeneProductLOC_Os02g39160 (Gramene Rice) hydroxymethylbutenyl 4-diphosphate synthase, putative, expressed//terpenoid biosynthetic process//sugar:hydrogen symporter activity//phosphoenolpyruvate-dependent sugar phosphotransferase system//4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase
LOC_Os02g45660GeneProductLOC_Os02g45660 (Gramene Rice) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplast precursor, putative, expressed//terpenoid biosynthetic process//2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
LOC_Os03g52170GeneProductLOC_Os03g52170 (Gramene Rice) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, putative, expressed//terpenoid biosynthetic process
LOC_Os05g33840GeneProductLOC_Os05g33840 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase//transketolase
LOC_Os05g34180GeneProductLOC_Os05g34180 (Gramene Rice) hydrolase, NUDIX family, domain containing protein, expressed//isoprenoid biosynthetic process//terpenoid biosynthetic process//isopentenyl-diphosphate delta-isomerase
LOC_Os06g05100GeneProductLOC_Os06g05100 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process//1-deoxy-D-xylulose-5-phosphate synthase
LOC_Os07g09190GeneProductLOC_Os07g09190 (Gramene Rice) transketolase, putative, expressed//terpenoid biosynthetic process
LOC_Os07g36190GeneProductLOC_Os07g36190 (Gramene Rice) hydrolase, NUDIX family, domain containing protein, expressed//isopentenyl-diphosphate delta-isomerase
LOC_Os07g40260GeneProductLOC_Os07g40260 (Gramene Rice) eukaryotic aspartyl protease domain containing protein, expressed
NAD(P)+Metabolite53-59-8 (CAS)
NAD(P)HMetaboliteCHEBI:13392 (ChEBI)
NADP+Metabolite53-59-8 (CAS)
NADPHMetabolite53-57-6 (CAS)
dimethylallyl-PPMetabolite358-71-4 (CAS)
diphosphateMetabolite2466-09-3 (CAS)
geranylgeranyldiphosphate biosynthesis II (plastidic)PathwayWP2211 (WikiPathways)
phytyl-PP biosynthesisPathway
polyisoprenoid biosynthesisPathway
protein disulfideProtein
protein dithiolProtein
pyruvateMetabolite127-17-3 (CAS)
Δ3-isopentenyl-PPMetaboliteC00129 (KEGG Compound)

Annotated Interactions

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