Cardiolipin Biosynthesis (Oryza sativa)

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1, 2EC:2.7.7.41LOC_Os03g17520LOC_Os01g58390LOC_Os01g57930LOC_Os02g05400L-1-phosphatidyl-glycerolCTP1,2-diacylglycerol-3-phosphateLOC_OS04G57500PhosphateCardiolipinDiphosphateH2Osn-glycerol-3-phosphateCMPCDP-diacylglycerolcardiolinin synthaseEC:3.1.3.27LOC_Os04g57500EC:2.7.8.5L-1-phosphatidylglycerol-phosphateCDP-diacylglycerolCMPLOC_Os01g57930


Description

Cardiolipin is one of the important phospholipid present in the inner membrane of mitochondria and plays an important role in ATP synthesis mediated by oxidative phosphorylation. Pathway is mirrored from the RiceCyc pathway database provided by the Gramene project (www.gramene.org). gene assignments are based on the sequence homology.

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Ontology Terms

 

Bibliography

  1. HOI SEON-KANG, TAKAHASHI EIJI, INATSU OSAMU, MANO YASUO, OHNISHI MASAO; ''Component Fatty Acids of Acidic Glycerophospholipids in Rice Grains: Universal Order of Unsaturation Index in Each Lipid among Varieties''; J Oleo Sci; VOL.54;NO.7;PAGE.369-373, 2005
  2. Frentzen M, Griebau R; ''Biosynthesis of Cardiolipin in Plant Mitochondria.''; Plant Physiol, 1994 PubMed Europe PMC

History

View all...
CompareRevisionActionTimeUserComment
107216view14:31, 17 September 2019MaintBotChEBI identifier normalization
84115view08:17, 16 January 2016EgonwFixed the data source name.
71856view20:31, 18 October 2013EgonwConnected an unconnected line and widened a metabolite label box.
69212view18:28, 8 July 2013MaintBotUpdated to 2013 gpml schema
67099view10:06, 26 June 2013Christine ChichesterOntology Term : 'cardiolipin biosynthetic pathway' added !
48988view22:52, 2 July 2012PjaiswalModified categories
48587view23:58, 5 June 2012PjaiswalModified description
48586view23:57, 5 June 2012Pjaiswaladded literature and fixed figure
48585view23:52, 5 June 2012PjaiswalModified description
48584view23:47, 5 June 2012PjaiswalNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
1,2-diacylglycerol-3-phosphateMetaboliteC00416 (KEGG Compound)
CDP-diacylglycerolMetaboliteCHEBI:17962 (ChEBI)
CMPMetabolite63-37-6 (CAS)
CTPMetabolite65-47-4 (CAS)
CardiolipinMetaboliteCHEBI:28494 (ChEBI)
DiphosphateMetabolite2466-09-3 (CAS)
EC:2.7.7.41GeneProduct2.7.7.41 (Enzyme Nomenclature)
EC:2.7.8.5GeneProduct2.7.8.5 (Enzyme Nomenclature)
EC:3.1.3.27GeneProduct3.1.3.27 (Enzyme Nomenclature)
H2OMetabolite7732-18-5 (CAS)
L-1-phosphatidyl-glycerolMetaboliteCHEBI:17517 (ChEBI)
L-1-phosphatidylglycerol-phosphateMetaboliteCHEBI:37393 (ChEBI)
LOC_OS04G57500GeneProductLOC_OS04G57500.1 (Gramene Rice) phosphatidate cytidylyltransferase, putative, expressed//phosphatidate cytidylyltransferase
LOC_Os01g57930GeneProductLOC_Os01g57930 (Gramene Rice) CDP-alcohol phosphatidyltransferase, putative, expressed//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
LOC_Os01g57930GeneProductLOC_Os01g58390 (Gramene Rice) Homolog of AT4G04870 (CLS).
LOC_Os01g58390GeneProductLOC_Os01g58390 (Gramene Rice) This is homologous to Yeast gene entry YHR100C from Uniprot P38812 (GEP4_YEAST). The sequence identity is about 33%, but was the best hit and has HAD-SF_ppase_IIIA domain. Arabidopsis homolog is AT3G58830.
LOC_Os02g05400GeneProductLOC_Os02g05400 (Gramene Rice) transmembrane protein 15, putative, expressed//phosphatidate cytidylyltransferase
LOC_Os03g17520GeneProductLOC_Os03g17520 (Gramene Rice) CDP-alcohol phosphatidyltransferase, putative, expressed//CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase//CDP-diacylglycerol-serine O-phosphatidyltransferase
LOC_Os04g57500GeneProductLOC_Os04g57500 (Gramene Rice) phosphatidate cytidylyltransferase, putative, expressed//phosphatidate cytidylyltransferase
PhosphateMetabolite14265-44-2 (CAS)
cardiolinin synthase GeneProduct2.7.8.- (Enzyme Nomenclature) Cardiolipin synthase. Arabidopsis homolog is AT4G04870 (CLS)
sn-glycerol-3-phosphateMetabolite57-03-4 (CAS)

Annotated Interactions

No annotated interactions

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