LEPRSTAT1STAT1IP3PIP3PIP2ProteinDAGLeptin Signaling PathwaycAMPReceptorProteinProteinfood intakemRNASmall moleculeLigandRegulation ofPLCG2SHC1PJAK2PPLCG1RAF1PTIMP1GRB2NCOA1 LEPLEPRPPIK3R2PPIK3R1PSTAT3STAT3PSH2B1 LEPSP1KHDRBS1PSOCS7PTPN11PSOCS3ERBB2PIGF1RESR1FYNPSRCPFOXO1PMTORPAKT1PRELAPCISHSOCS2IKBKGPCHUKPIKBKBPACACBPMAPK8PEIF4EPEIF4EBP1PSTAT5BPGSK3BPPTENPMAP2K2PMAP2K1PMAPK14PACACAPGSK3APBAXNOS3PPTK2PCFL2PRPS6PCREB1PPRKAA2PBADPRPS6KA1 PIRS2PIRS1PSOS1HRASGTPMAPK1PMAPK3PSTAT3STAT3PPTPN1STAT3STAT1PSTAT3STAT1PSTAT1PSTAT1PESR1ESR1ESR1PDE3BRELAPNFKB1RELRELBCL2L1ELK1PAMPEGFRPRPS6KB1PIL1RNIL1BPRKAA1PCREB1PCCND1JAK1PRHOAROCK1CDC42RAC1NFKB1CYNUCYNUCYNUROCK2CYNUCYNUCa2+ signalingPKC pathwayActin cytoskeletalreorganizationCYNUInduced activationEnzyme complexInhibitionAuto catalysisTransportPositive regulation of gene expressionLeads to through unknown mechanismNegative regulation of gene expressionTranslocation UbiquitinationDeubiquitinationSumoylationInduced catalysisProtein-protein interactionAcetylationDephosphorylationLEGENDPhosphorylationDeacetylationGolgi apparatusEndosomeNucleusMitochondrionDesumoylationMethylationDemethylationPalmitoylationCytoplasmECPlasma membraneMTEndoplasmic reticulumCYPMGONUExtracellularERENProteolytic cleavageMolecule